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> Protein (NX_Q96JJ7)
Protein (NX_Q96JJ7)
Protein
Gene SymbolTMX3 to neXtProt (NX_Q96JJ7)
DescriptionProtein disulfide-isomerase TMX3
Chromosome18
Location18q22.1 (66340925 ~ 66382535) to Ensembl
Sequene Features : Isoforms 2, Variants 53, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cell redox homeostasis
.response to endoplasmic reticulum stress
.protein folding
.protein disulfide isomerase activity .integral component of membrane
.cell surface
.endoplasmic reticulum membrane
.endoplasmic reticulum
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 53 5
2014-09-19protein level
2 39 5
2014-05-27protein level
2 39 5
2014-02-25protein level
2 39 5
2013-12-09protein level
2 32 5
2013-11-01protein level
2 29 5
2013-09-12protein level
2 29 5
2013-08-17protein level
2 29 5
2013-07-15protein level
2 21 3
2013-06-11protein level
2 21 3
2013-02-12protein level
2 11 5
2012-12-20protein level
2 11 5
2012-10-30protein level
2 13 5
2012-10-07protein level
2 13 4
2012-08-24protein level
2 10 4
2012-07-28protein level
2 10 4
2012-06-08protein level
2 10 4
2012-05-07protein level
2 10 4
2012-04-10protein level
2 10 4
2012-01-13protein level
2 1 4
2011-12-20protein level
2 1 4
2011-11-11protein level
2 1 4
2011-08-23protein level
2 1 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96JJ7-1
13 9 0 51838.7568
NX_Q96JJ7-2
1 9 0 22276.235
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2514069,EBI-741101 FHL3  
  .actin cytoskeleton organization
.muscle organ development
.zinc ion binding .Z disc
.focal adhesion
.nucleus
.stress fiber
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland60
ascites25
blood24
bone55
bone marrow20
brain76
connective tissue13
ear248
embryonic tissue65
esophagus49
eye23
intestine12
kidney42
liver43
lung14
lymph node55
mammary gland66
mouth30
muscle9
nerve128
ovary9
pancreas9
parathyroid48
placenta42
prostate26
skin28
stomach20
testis41
thymus75
thyroid21
trachea193
uterus68
vascular58
Health State
TissuesTPM*
normal46
adrenal tumor79
breast (mammary gland) tumor42
chondrosarcoma12
esophageal tumor57
gastrointestinal tumor42
germ cell tumor15
glioma18
head and neck tumor14
kidney tumor58
leukemia21
liver tumor20
lymphoma13
non-neoplasia10
ovarian tumor13
primitive neuroectodermal tumor of the CNS15
prostate cancer38
retinoblastoma21
skin tumor31
soft tissue/muscle tissue tumor23
uterine tumor66
Developmental Stage
TissuesTPM*
adult33
embryoid body100
blastocyst65
neonate96
fetus30
infant42
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue23.9
adrenal gland20.2
appendix36.3
bone marrow18.2
cerebral cortex25.6
colon18
duodenum36.2
esophagus17.2
gallbladder23
heart muscle19
kidney21.2
liver13.1
lung27.3
lymph node37.1
ovary21.3
pancreas6.1
placenta18.3
prostate29.6
salivary gland10.3
skin17.6
small intestine38.2
spleen31.6
stomach21.3
testis23.6
thyroid gland26
urinary bladder25.9
Tissues
TissuesExpression level
adrenal glandHigh
appendixMedium
bone marrowHigh
breastMedium
bronchusMedium
cerebellumMedium
cerebral cortexMedium
cervix, uterineMedium
colonHigh
duodenumHigh
endometrium 1Medium
endometrium 2Medium
epididymisMedium
esophagusMedium
fallopian tubeMedium
gallbladderMedium
heart muscleHigh
hippocampusMedium
kidneyMedium
lateral ventricleMedium
liverMedium
lungMedium
lymph nodeMedium
nasopharynxMedium
oral mucosaLow
ovaryLow
pancreasMedium
placentaHigh
prostateMedium
rectumHigh
salivary glandMedium
seminal vesicleMedium
skeletal muscleHigh
skin 1Medium
skin 2Low
small intestineMedium
smooth muscleMedium
soft tissue 1Medium
soft tissue 2Medium
spleenHigh
stomach 1High
stomach 2Medium
testisMedium
thyroid glandHigh
tonsilMedium
urinary bladderMedium
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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