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> Protein (NX_Q96K83)
Protein (NX_Q96K83)
Protein
Gene SymbolZNF521 to neXtProt (NX_Q96K83)
DescriptionZinc finger protein 521
Chromosome18
Location18q11.2 (22641890 ~ 22932154) to Ensembl
Sequene Features : Isoforms 1, Variants 273, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cell differentiation
.multicellular organismal development
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.protein domain specific binding
.DNA binding
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 273 2
2014-09-19protein level
1 210 2
2014-05-27protein level
1 210 2
2014-02-25protein level
1 208 2
2013-12-09protein level
1 187 2
2013-11-01protein level
1 184 2
2013-09-12protein level
1 184 2
2013-08-17protein level
1 184 2
2013-07-15protein level
1 143 2
2013-06-11protein level
1 143 2
2013-02-12protein level
1 40 2
2012-12-20protein level
1 43 2
2012-10-30protein level
1 52 2
2012-10-07protein level
1 52 2
2012-08-24protein level
1 23 2
2012-07-28protein level
1 23 2
2012-06-08protein level
1 33 2
2012-05-07protein level
1 33 2
2012-04-10protein level
1 33 2
2012-01-13protein level
1 24 2
2011-12-20protein level
1 24 2
2011-11-11protein level
1 24 2
2011-08-23protein level
1 24 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96K83-1
58 0 7 147769.2051
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bone13
brain67
connective tissue53
ear248
embryonic tissue75
eye14
heart22
intestine4
kidney37
lung29
lymph node11
mouth15
muscle28
pancreas14
pituitary gland121
placenta10
skin9
spleen18
testis11
trachea57
umbilical cord290
uterus21
vascular38
Health State
TissuesTPM*
normal41
chondrosarcoma24
germ cell tumor22
glioma9
head and neck tumor7
kidney tumor29
lung tumor19
lymphoma13
non-neoplasia51
pancreatic tumor28
skin tumor7
soft tissue/muscle tissue tumor47
Developmental Stage
TissuesTPM*
adult13
embryoid body85
blastocyst65
neonate128
fetus44
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue10.6
adrenal gland16.8
appendix5.1
bone marrow1.9
cerebral cortex12.6
colon4.7
duodenum3.2
esophagus7.8
gallbladder15.5
heart muscle9.3
kidney4.8
lung8.2
lymph node6.8
ovary27.3
placenta7.6
prostate3.5
salivary gland8
skin6.1
small intestine3.6
spleen23.7
stomach2.9
testis5.9
thyroid gland8.4
urinary bladder15.4
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowMedium
breastMedium
bronchusMedium
cerebellumHigh
cerebral cortexHigh
cervix, uterineHigh
colonMedium
duodenumMedium
endometrium 1Medium
endometrium 2Medium
epididymisMedium
esophagusHigh
fallopian tubeMedium
gallbladderMedium
heart muscleMedium
hippocampusHigh
kidneyMedium
lateral ventricleHigh
lungMedium
lymph nodeMedium
nasopharynxMedium
oral mucosaMedium
ovaryMedium
pancreasMedium
parathyroid glandMedium
placentaHigh
prostateMedium
rectumHigh
salivary glandLow
seminal vesicleLow
skeletal muscleMedium
skin 1Medium
skin 2High
small intestineMedium
smooth muscleMedium
soft tissue 1Medium
soft tissue 2Low
spleenMedium
stomach 1Medium
stomach 2Medium
testisMedium
thyroid glandMedium
tonsilHigh
urinary bladderMedium
vaginaHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*610974, gene) Zinc finger protein 521; ZNF521OMIM
2acute lymphocytic leukemiaCGP


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