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> Protein (NX_Q96LA5)
Protein (NX_Q96LA5)
Protein
Gene SymbolFCRL2 to neXtProt (NX_Q96LA5)
DescriptionFc receptor-like protein 2
Chromosome1
Location1q23.1 (157715523 ~ 157746922) to Ensembl
Sequene Features : Isoforms 5, Variants 116, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of signal transduction
.cell-cell signaling
.SH3/SH2 adaptor activity .integral component of membrane
.plasma membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
5 116 8
2014-09-19protein level
5 84 8
2014-05-27protein level
5 84 8
2014-02-25protein level
5 85 8
2013-12-09protein level
5 70 8
2013-11-01protein level
5 69 8
2013-09-12protein level
5 69 8
2013-08-17protein level
5 69 8
2013-07-15protein level
5 48 8
2013-06-11protein level
5 48 8
2013-02-12protein level
5 25 20
2012-12-20protein level
5 25 20
2012-10-30protein level
5 28 20
2012-10-07protein level
5 28 8
2012-08-24protein level
5 17 8
2012-07-28protein level
5 18 8
2012-06-08protein level
5 1 8
2012-05-07protein level
5 1 8
2012-04-10protein level
5 1 8
2012-01-13protein level
5 1 8
2011-12-20protein level
5 1 8
2011-11-11protein level
5 1 8
2011-08-23protein level
5 1 8
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96LA5-1
11 10 0 55506.8982
NX_Q96LA5-2
0 8 0 27528.5375
NX_Q96LA5-3
1 5 0 20666.2891
NX_Q96LA5-4
1 3 0 15363.557
NX_Q96LA5-5
2 7 0 22518.4585
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10185081,EBI-713635 NCK2  
  .negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
.ephrin receptor signaling pathway
.vascular endothelial growth factor receptor signaling pathway
  + 16 more...
.receptor signaling complex scaffold activity
.cytoskeletal adaptor activity
.SH3/SH2 adaptor activity
.vesicle membrane
.cytosol
.endoplasmic reticulum
.cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood8
connective tissue6
lung2
lymph90
lymph node100
mouth90
spleen56
thymus12
uterus8
Health State
TissuesTPM*
normal4
germ cell tumor7
head and neck tumor44
lymphoma69
non-neoplasia10
uterine tumor22
Developmental Stage
TissuesTPM*
adult3
fetus5
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
appendix18.2
bone marrow2.2
colon2.3
duodenum2.8
gallbladder1.1
lymph node30.6
small intestine2.7
spleen25.8
stomach2.7
urinary bladder3.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*606509, gene) Fc receptor-like protein 2; FCRL2OMIM


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