Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q96LC9)
Protein (NX_Q96LC9)
Protein
Gene SymbolBMF to neXtProt (NX_Q96LC9)
DescriptionBcl-2-modifying factor
Chromosome15
Location15q15.1 (40380091 ~ 40401093) to Ensembl
Sequene Features : Isoforms 3, Variants 17, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of intrinsic apoptotic signaling pathway
.negative regulation of apoptotic signaling pathway
.positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
  + 6 more...
.N/A .myosin complex
.plasma membrane
.cytosol
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 17 0
2014-09-19protein level
3 13 0
2014-05-27transcript level
3 13 0
2014-02-25transcript level
3 13 0
2013-12-09transcript level
3 11 0
2013-11-01transcript level
3 9 0
2013-09-12transcript level
3 9 0
2013-08-17transcript level
3 9 0
2013-07-15transcript level
3 6 0
2013-06-11transcript level
3 6 0
2013-02-12transcript level
3 3 0
2012-12-20transcript level
3 2 0
2012-10-30transcript level
3 3 0
2012-10-07transcript level
3 3 0
2012-08-24transcript level
3 3 0
2012-07-28transcript level
3 3 0
2012-06-08transcript level
3 5 0
2012-05-07transcript level
3 5 0
2012-04-10transcript level
3 5 0
2012-01-13transcript level
3 3 0
2011-12-20transcript level
3 3 0
2011-11-11transcript level
3 3 0
2011-08-23transcript level
3 3 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96LC9-1
3 5 0 20495.0626
NX_Q96LC9-2
1 5 0 17982.7105
NX_Q96LC9-3
2 3 0 14140.7407
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-3919268,EBI-307352 REL  
  .negative regulation of neuron death
.positive regulation of transcription from RNA polymerase II promoter
.innate immune response
  + 10 more...
.sequence-specific DNA binding transcription factor activity
.chromatin binding
.RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.RNA polymerase II distal enhancer sequence-specific DNA binding
.I-kappaB/NF-kappaB complex
.cytosol
.transcription factor complex
  + 2 more...
2 EBI-3919268,EBI-78035 BCL2L1  
  .positive regulation of intrinsic apoptotic signaling pathway
.negative regulation of intrinsic apoptotic signaling pathway
.negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
  + 42 more...
.BH3 domain binding
.protein heterodimerization activity
.protein homodimerization activity
  + 2 more...
.Bcl-2 family protein complex
.nuclear membrane
.synaptic vesicle membrane
  + 11 more...
3 EBI-3919268,EBI-707714 BCL2L2  
  .negative regulation of intrinsic apoptotic signaling pathway
.extrinsic apoptotic signaling pathway in absence of ligand
.Sertoli cell proliferation
  + 3 more...
.protein heterodimerization activity
.protein homodimerization activity
.extracellular exosome
.cytosol
.mitochondrial outer membrane
4 EBI-3919268,EBI-742371 DYNLL2  
  .positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
.intrinsic apoptotic signaling pathway
.antigen processing and presentation of exogenous peptide antigen via MHC class II
  + 6 more...
.motor activity .ciliary tip
.primary cilium
.dynein complex
  + 7 more...
5 EBI-3919268,EBI-1105213 TFIP11  
  .biomineral tissue development
.RNA processing
.regulation of transcription, DNA-templated
  + 2 more...
.DNA binding .catalytic step 2 spliceosome
.U2-type post-mRNA release spliceosomal complex
.nuclear speck
  + 3 more...
6 EBI-3919268,EBI-10320311 SEC14L4  
  .N/A .lipid binding
.transporter activity
.integral component of membrane
.intracellular
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder33
blood89
bone13
brain5
connective tissue20
embryonic tissue79
eye4
heart11
intestine8
kidney18
larynx170
liver4
lung26
lymph293
lymph node89
mammary gland6
ovary19
pancreas32
placenta38
prostate26
skin33
thymus25
thyroid21
trachea19
uterus17
vascular19
Health State
TissuesTPM*
normal19
bladder carcinoma56
breast (mammary gland) tumor10
chondrosarcoma24
colorectal tumor8
germ cell tumor34
glioma18
head and neck tumor37
kidney tumor58
leukemia63
liver tumor10
lung tumor19
lymphoma193
non-neoplasia20
ovarian tumor26
pancreatic tumor28
retinoblastoma21
skin tumor7
soft tissue/muscle tissue tumor15
uterine tumor11
Developmental Stage
TissuesTPM*
adult19
embryoid body114
blastocyst65
neonate32
fetus7
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue3
adrenal gland2.4
appendix10
bone marrow16.4
cerebral cortex1.3
colon7.8
duodenum16
esophagus2.4
gallbladder10.6
heart muscle3.7
kidney7.7
liver2
lung11.6
lymph node12.2
ovary13
pancreas2.4
placenta6.4
prostate4.8
salivary gland6.7
skin4.2
small intestine15.3
spleen14.3
stomach8.6
testis2.9
thyroid gland13.1
urinary bladder10.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*606266, gene) Bcl2-modifying factor; BMFOMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center