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> Protein (NX_Q96LK0)
Protein (NX_Q96LK0)
Protein
Gene SymbolCEP19 to neXtProt (NX_Q96LK0)
DescriptionCentrosomal protein of 19 kDa
Chromosome3
Location3q29 (196433148 ~ 196439164) to Ensembl
Sequene Features : Isoforms 1, Variants 24, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .ciliary basal body
.centriole
.spindle pole
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 24 0
2014-09-19protein level
1 21 0
2014-05-27protein level
1 21 0
2014-02-25protein level
1 21 0
2013-12-09protein level
1 14 0
2013-11-01protein level
1 14 0
2013-09-12protein level
1 14 0
2013-08-17protein level
1 14 0
2013-07-15protein level
1 8 0
2013-06-11protein level
1 8 0
2013-02-12protein level
1 3 0
2012-12-20protein level
1 4 0
2012-10-30protein level
1 7 0
2012-10-07protein level
1 7 0
2012-08-24protein level
1 5 0
2012-07-28protein level
1 5 0
2012-06-08protein level
1 5 0
2012-05-07protein level
1 5 0
2012-04-10protein level
1 5 0
2012-01-13protein level
1 1 0
2011-12-20protein level
1 1 0
2011-11-11protein level
1 1 0
2011-08-23protein level
1 1 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96LK0-1
6 0 0 19153.5184
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-741885,EBI-10176632 ZBTB14  
  .negative regulation of transcription, DNA-templated
.transcription from RNA polymerase II promoter
.negative regulation of transcription from RNA polymerase II promoter
.metal ion binding
.transcription regulatory region DNA binding
.sequence-specific DNA binding
  + 2 more...
.cytoplasm
.nucleoplasm
.nucleus
2 EBI-741885,EBI-1266334 FGFR1OP  
  .negative regulation of protein tyrosine kinase activity
.microtubule anchoring
.positive regulation of cell migration
  + 7 more...
.protein homodimerization activity
.protein tyrosine kinase inhibitor activity
.protein kinase binding
.protein tyrosine kinase activity
.perinuclear region of cytoplasm
.cytosol
.centrosome
.nucleus
3 EBI-741885,EBI-307352 REL  
  .negative regulation of neuron death
.positive regulation of transcription from RNA polymerase II promoter
.innate immune response
  + 10 more...
.sequence-specific DNA binding transcription factor activity
.chromatin binding
.RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.RNA polymerase II distal enhancer sequence-specific DNA binding
.I-kappaB/NF-kappaB complex
.cytosol
.transcription factor complex
  + 2 more...
4 EBI-741885,EBI-7131783 SYNE4  
  .establishment of epithelial cell apical/basal polarity .N/A .LINC complex
.integral component of nuclear outer membrane
5 EBI-741885,EBI-10181113 KIAA1958  
  .N/A .N/A .N/A
6 EBI-741885,EBI-739657 KXD1  
  .vesicle-mediated transport .N/A .BLOC-1 complex
7 EBI-741885,EBI-749920 CALCOCO1  
  .positive regulation of transcription from RNA polymerase II promoter
.positive regulation of transcription, DNA-templated
.intracellular steroid hormone receptor signaling pathway
  + 3 more...
.armadillo repeat domain binding
.transcription regulatory region DNA binding
.sequence-specific DNA binding
  + 6 more...
.intracellular membrane-bounded organelle
.cytoplasm
.nucleus
.nuclear chromatin
8 EBI-741885,EBI-4402837 RABL2A  
  .Rab protein signal transduction
.metabolic process
.intracellular protein transport
.GTP binding
.GTPase activity
.endomembrane system
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood16
bone13
brain11
embryonic tissue4
eye19
heart55
liver24
lung5
pituitary gland60
skin4
testis13
Health State
TissuesTPM*
normal8
germ cell tumor3
glioma9
liver tumor10
lung tumor9
primitive neuroectodermal tumor of the CNS7
retinoblastoma64
skin tumor7
Developmental Stage
TissuesTPM*
adult3
fetus23
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue1.4
adrenal gland2.6
appendix3.2
cerebral cortex3.1
colon1.2
esophagus1.7
gallbladder2.1
heart muscle1
kidney2.8
lung1.5
lymph node2.9
ovary1.9
placenta1.5
prostate1.9
skin1.1
spleen2.8
testis10.3
thyroid gland2.2
urinary bladder2.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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