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> Protein (NX_Q96M63)
Protein (NX_Q96M63)
Protein
Gene SymbolCCDC114 to neXtProt (NX_Q96M63)
DescriptionCoiled-coil domain-containing protein 114
Chromosome19
Location19q13.33 (48799714 ~ 48825151) to Ensembl
Sequene Features : Isoforms 3, Variants 112, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.outer dynein arm assembly .N/A .outer dynein arm
.cilium
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 112 0
2014-09-19transcript level
3 89 0
2014-05-27transcript level
3 89 0
2014-02-25transcript level
3 88 0
2013-12-09transcript level
3 54 0
2013-11-01transcript level
3 53 0
2013-09-12transcript level
3 53 0
2013-08-17transcript level
3 53 0
2013-07-15transcript level
3 42 0
2013-06-11transcript level
3 42 0
2013-02-12transcript level
3 31 0
2012-12-20transcript level
3 32 0
2012-10-30transcript level
3 39 0
2012-10-07transcript level
3 39 0
2012-08-24transcript level
3 33 0
2012-07-28transcript level
3 35 0
2012-06-08transcript level
3 36 0
2012-05-07transcript level
3 36 0
2012-04-10transcript level
3 36 0
2012-01-13transcript level
3 20 0
2011-12-20transcript level
3 20 0
2011-11-11transcript level
3 20 0
2011-08-23transcript level
3 20 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96M63-1
0 30 0 75000.2185
NX_Q96M63-4
1 22 0 50345.0971
NX_Q96M63-5
2 22 0 62655.5221
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10173858,EBI-8466445 CCDC151  
  .regulation of cilium assembly
.cell projection organization
.cilium movement
.N/A .ciliary basal body
.axoneme
.cilium
.centriole
2 EBI-10173858,EBI-740220 HGS  
  .positive regulation of exosomal secretion
.protein localization to membrane
.membrane organization
  + 13 more...
.metal ion binding
.protein domain specific binding
.extracellular exosome
.intracellular membrane-bounded organelle
.multivesicular body membrane
  + 6 more...
3 EBI-10173858,EBI-721019 KLC1  
  .stress granule disassembly
.antigen processing and presentation of exogenous peptide antigen via MHC class II
.viral process
  + 4 more...
.microtubule motor activity
.motor activity
.growth cone
.cytoplasmic membrane-bounded vesicle
.membrane
  + 3 more...
4 EBI-10173858,EBI-747505 C1orf216  
  .N/A .N/A .N/A
5 EBI-10173858,EBI-739832 LNX1  
  .protein homooligomerization
.protein ubiquitination involved in ubiquitin-dependent protein catabolic process
.ligase activity
.zinc ion binding
.ubiquitin-protein transferase activity
.cytoplasm
6 EBI-10173858,EBI-2514791 HAUS1  
  .cell division
.centrosome organization
.spindle assembly
.mitotic nuclear division
.N/A .HAUS complex
.microtubule
.centrosome
  + 2 more...
7 EBI-10173858,EBI-2932492 TXN2  
  .oxidation-reduction process
.response to axon injury
.cell redox homeostasis
  + 12 more...
.peptide-methionine (R)-S-oxide reductase activity
.oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
.protein disulfide oxidoreductase activity
.peptide-methionine (S)-S-oxide reductase activity
.neuronal cell body
.dendrite
.mitochondrial matrix
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain3
connective tissue6
lung2
stomach10
testis66
trachea96
uterus4
Health State
TissuesTPM*
normal5
chondrosarcoma12
gastrointestinal tumor8
uterine tumor11
Developmental Stage
TissuesTPM*
adult2
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
lung5.9
ovary1.9
skin1.1
testis29.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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