Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q96MU7)
Protein (NX_Q96MU7)
Protein
Gene SymbolYTHDC1 to neXtProt (NX_Q96MU7)
DescriptionYTH domain-containing protein 1
Chromosome4
Location4q13.2 (69176105 ~ 69215807) to Ensembl
Sequene Features : Isoforms 2, Variants 102, PTMs 16 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.mRNA splice site selection .N6-methyladenosine-containing RNA binding
.poly(A) RNA binding
.RNA binding
.nuclear body
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 102 16
2014-09-19protein level
2 67 17
2014-05-27protein level
2 67 17
2014-02-25protein level
2 67 17
2013-12-09protein level
2 61 17
2013-11-01protein level
2 61 16
2013-09-12protein level
2 61 16
2013-08-17protein level
2 61 16
2013-07-15protein level
2 29 16
2013-06-11protein level
2 29 16
2013-02-12protein level
2 10 39
2012-12-20protein level
2 9 39
2012-10-30protein level
2 10 39
2012-10-07protein level
2 10 20
2012-08-24protein level
2 5 20
2012-07-28protein level
2 5 20
2012-06-08protein level
2 6 20
2012-05-07protein level
2 6 20
2012-04-10protein level
2 6 20
2012-01-13protein level
2 5 20
2011-12-20protein level
2 5 20
2011-11-11protein level
2 5 19
2011-08-23protein level
2 5 19
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96MU7-1
1 20 0 84649.0811
NX_Q96MU7-2
1 20 0 82641.9537
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2849854,EBI-722504 KHDRBS3  
  .spermatogenesis
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.poly(A) RNA binding
.RNA binding
.nucleoplasm
.nucleus
2 EBI-2849854,EBI-750020 CLK2  
  .protein autophosphorylation
.negative regulation of gluconeogenesis
.regulation of RNA splicing
  + 3 more...
.ATP binding
.protein tyrosine kinase activity
.protein serine/threonine/tyrosine kinase activity
.protein serine/threonine kinase activity
.nuclear speck
.nucleoplasm
.nucleus
3 EBI-2849854,EBI-593303 SRPK2  
  .regulation of mRNA splicing, via spliceosome
.positive regulation of cell cycle
.innate immune response
  + 12 more...
.14-3-3 protein binding
.poly(A) RNA binding
.ATP binding
  + 2 more...
.cytoplasm
.nucleolus
.nucleoplasm
.nucleus
4 EBI-2849854,EBI-8642021 RBMY1F  
  .RNA splicing
.spermatogenesis
.mRNA processing
.RNA binding
.nucleotide binding
.nucleus
5 EBI-2849854,EBI-742808 KHDRBS2  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.poly(U) RNA binding
.poly(A) binding
.nucleus
6 EBI-2849854,EBI-739789 DVL3  
  .positive regulation of canonical Wnt signaling pathway
.planar cell polarity pathway involved in neural tube closure
.cochlea morphogenesis
  + 12 more...
.protein heterodimerization activity
.beta-catenin binding
.frizzled binding
  + 2 more...
.cytosol
7 EBI-2849854,EBI-539478 SRPK1  
  .regulation of mRNA processing
.regulation of mRNA splicing, via spliceosome
.innate immune response
  + 9 more...
.poly(A) RNA binding
.ATP binding
.protein serine/threonine kinase activity
  + 2 more...
.nuclear matrix
.plasma membrane
.endoplasmic reticulum
  + 3 more...
8 EBI-2849854,EBI-742426 SDCBP2  
  .intracellular transport
.intracellular signal transduction
.nervous system development
.protein heterodimerization activity
.protein homodimerization activity
.protein C-terminus binding
.extracellular exosome
.plasma membrane
.cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland30
bladder167
blood40
bone83
bone marrow41
brain52
cervix20
connective tissue53
embryonic tissue65
esophagus49
eye90
heart100
intestine68
kidney109
larynx42
liver82
lung53
lymph22
lymph node111
mammary gland52
mouth75
muscle9
nerve128
ovary59
pancreas89
parathyroid48
pharynx24
pituitary gland121
placenta81
prostate58
salivary gland49
skin42
spleen37
stomach94
testis57
thymus125
thyroid64
trachea96
uterus133
vascular96
Health State
TissuesTPM*
normal78
bladder carcinoma170
breast (mammary gland) tumor64
cervical tumor28
chondrosarcoma72
colorectal tumor88
esophageal tumor57
gastrointestinal tumor59
germ cell tumor91
glioma18
head and neck tumor67
kidney tumor101
leukemia116
liver tumor83
lung tumor29
lymphoma13
non-neoplasia31
ovarian tumor78
pancreatic tumor95
primitive neuroectodermal tumor of the CNS7
prostate cancer28
retinoblastoma21
skin tumor47
soft tissue/muscle tissue tumor63
uterine tumor110
Developmental Stage
TissuesTPM*
adult80
embryoid body42
blastocyst113
fetus78
infant42
juvenile71
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue32.5
adrenal gland35.6
appendix48.4
bone marrow111.5
cerebral cortex35
colon36.3
duodenum33.5
esophagus43.2
gallbladder39.7
heart muscle30.6
kidney40.6
liver23.7
lung40.8
lymph node61.9
ovary79.9
pancreas22
placenta57.7
prostate43.3
salivary gland34.9
skin41.3
small intestine37.8
spleen54.4
stomach42.8
testis41.3
thyroid gland41.7
urinary bladder42.8
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowHigh
breastHigh
bronchusHigh
cerebellumHigh
cerebral cortexHigh
cervix, uterineHigh
colonHigh
duodenumHigh
endometrium 1Low
endometrium 2Medium
epididymisHigh
esophagusHigh
fallopian tubeHigh
gallbladderHigh
heart muscleMedium
hippocampusHigh
kidneyMedium
lateral ventricleHigh
liverMedium
lungMedium
lymph nodeMedium
nasopharynxHigh
ovaryMedium
pancreasHigh
parathyroid glandHigh
placentaHigh
prostateMedium
rectumHigh
salivary glandMedium
seminal vesicleMedium
skeletal muscleMedium
skin 2High
small intestineMedium
smooth muscleMedium
soft tissue 1Medium
spleenLow
stomach 1High
stomach 2High
testisHigh
thyroid glandHigh
tonsilHigh
urinary bladderHigh
vaginaHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center