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> Protein (NX_Q96NC0)
Protein (NX_Q96NC0)
Protein
Gene SymbolZMAT2 to neXtProt (NX_Q96NC0)
DescriptionZinc finger matrin-type protein 2
Chromosome5
Location5q31.3 (140078265 ~ 140086248) to Ensembl
Sequene Features : Isoforms 1, Variants 15, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .zinc ion binding
.DNA binding
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 15 2
2014-09-19protein level
1 12 2
2014-05-27protein level
1 12 2
2014-02-25protein level
1 12 2
2013-12-09protein level
1 11 2
2013-11-01protein level
1 11 2
2013-09-12protein level
1 11 1
2013-08-17protein level
1 11 1
2013-07-15protein level
1 4 0
2013-06-11protein level
1 4 0
2013-02-12protein level
1 2 0
2012-12-20protein level
1 2 0
2012-10-30protein level
1 2 0
2012-10-07protein level
1 2 0
2012-08-24protein level
1 2 0
2012-07-28protein level
1 2 0
2012-06-08protein level
1 2 0
2012-05-07protein level
1 2 0
2012-04-10protein level
1 2 0
2012-01-13protein level
1 1 0
2011-12-20protein level
1 1 0
2011-11-11protein level
1 1 0
2011-08-23protein level
1 1 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96NC0-1
5 0 0 23596.8821
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2682299,EBI-5661036 FSD2  
  .N/A .N/A .N/A
2 EBI-2682299,EBI-10176632 ZBTB14  
  .negative regulation of transcription, DNA-templated
.transcription from RNA polymerase II promoter
.negative regulation of transcription from RNA polymerase II promoter
.metal ion binding
.transcription regulatory region DNA binding
.sequence-specific DNA binding
  + 2 more...
.cytoplasm
.nucleoplasm
.nucleus
3 EBI-2682299,EBI-741602 TRIM37  
  .aggresome assembly
.protein autoubiquitination
.positive regulation of NF-kappaB transcription factor activity
  + 7 more...
.ubiquitin protein ligase activity
.protein homodimerization activity
.ubiquitin protein ligase binding
  + 5 more...
.perinuclear region of cytoplasm
.aggresome
.cytosol
  + 2 more...
4 EBI-2682299,EBI-466029 HTT  
  .negative regulation of extrinsic apoptotic signaling pathway
.iron ion homeostasis
.L-glutamate import
  + 38 more...
.diazepam binding
.beta-tubulin binding
.dynein intermediate chain binding
  + 6 more...
.protein complex
.cytoplasmic vesicle membrane
.dendrite
  + 11 more...
5 EBI-2682299,EBI-740459 FXR2  
  .negative regulation of translation
.positive regulation of defense response to virus by host
.poly(A) RNA binding
.identical protein binding
.mRNA binding
.RNA binding
.extracellular exosome
.cytosolic large ribosomal subunit
.membrane
  + 3 more...
6 EBI-2682299,EBI-618309 GOLGA2  
  .negative regulation of protein binding
.mitotic cell cycle
.syntaxin binding
.protein kinase binding
.Golgi cisterna membrane
.ER to Golgi transport vesicle
.cis-Golgi network
  + 4 more...
7 EBI-2682299,EBI-355744 TRAF2  
  .positive regulation of extrinsic apoptotic signaling pathway
.regulation of extrinsic apoptotic signaling pathway via death domain receptors
.negative regulation of neuron death
  + 35 more...
.sphingolipid binding
.identical protein binding
.thioesterase binding
  + 10 more...
.IRE1-TRAF2-ASK1 complex
.TRAF2-GSTP1 complex
.membrane raft
  + 7 more...
8 EBI-2682299,EBI-745305 IKZF1  
  .retina development in camera-type eye
.positive regulation of NK T cell differentiation
.Peyer's patch development
  + 17 more...
.metal ion binding
.sequence-specific DNA binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.protein complex
.cytoplasm
.pericentric heterochromatin
.nucleus
9 EBI-2682299,EBI-2808286 CCDC57  
  .N/A .N/A .N/A
10 EBI-2682299,EBI-742948 MTUS2  
  .N/A .protein homodimerization activity
.microtubule binding
.microtubule
.cytoplasm
.nucleus
11 EBI-2682299,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
12 EBI-2682299,EBI-2549423 HMBOX1  
  .positive regulation of transcription, DNA-templated
.negative regulation of transcription, DNA-templated
.transcription, DNA-templated
.DNA binding .cytoplasm
.nucleoplasm
.nucleus
13 EBI-2682299,EBI-713786 PHC2  
  .cellular protein metabolic process
.post-translational protein modification
.protein sumoylation
  + 2 more...
.identical protein binding
.zinc ion binding
.DNA binding
.PRC1 complex
.PcG protein complex
.nucleoplasm
  + 2 more...
14 EBI-2682299,EBI-2799833 VPS52  
  .embryonic ectodermal digestive tract development
.protein transport
.ectodermal cell differentiation
.syntaxin binding .perinuclear region of cytoplasm
.endosome membrane
.Golgi apparatus
15 EBI-2682299,EBI-741724 SPERT  
  .N/A .N/A .cytoplasmic membrane-bounded vesicle
16 EBI-2682299,EBI-742887 CEP76  
  .regulation of centriole replication
.organelle organization
.mitotic cell cycle
.G2/M transition of mitotic cell cycle
.N/A .protein complex
.cytosol
.centriole
.centrosome
17 EBI-2682299,EBI-742740 ZBTB8A  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
18 EBI-2682299,EBI-8466265 AK8  
  .ventricular system development
.nucleoside triphosphate biosynthetic process
.nucleoside diphosphate phosphorylation
.ATP binding
.nucleoside diphosphate kinase activity
.cytidylate kinase activity
.adenylate kinase activity
.cytosol
19 EBI-2682299,EBI-413317 SPAG5  
  .regulation of attachment of spindle microtubules to kinetochore
.cell division
.chromosome segregation
  + 2 more...
.N/A .mitotic spindle
.microtubule plus-end
.midbody
  + 7 more...
20 EBI-2682299,EBI-741037 LZTS2  
  .negative regulation of protein localization to nucleus
.negative regulation of canonical Wnt signaling pathway
.spindle midzone assembly
  + 7 more...
.N/A .midbody
.microtubule
.centrosome
.cytoplasm
21 EBI-2682299,EBI-2341518 TRIM36  
  .regulation of cell cycle
.acrosome reaction
.ligase activity
.zinc ion binding
.ubiquitin-protein transferase activity
.extracellular exosome
.cytoskeleton
.acrosomal vesicle
22 EBI-2682299,EBI-1105213 TFIP11  
  .biomineral tissue development
.RNA processing
.regulation of transcription, DNA-templated
  + 2 more...
.DNA binding .catalytic step 2 spliceosome
.U2-type post-mRNA release spliceosomal complex
.nuclear speck
  + 3 more...
23 EBI-2682299,EBI-2212028 SSX2IP  
  .regulation of cell motility
.centrosome organization
.cilium assembly
  + 3 more...
.N/A .protein complex
.ciliary basal body
.centriolar satellite
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland30
bladder33
blood106
bone83
bone marrow82
brain47
cervix103
connective tissue26
ear124
embryonic tissue98
esophagus49
eye43
heart33
intestine43
kidney28
liver43
lung68
lymph90
mammary gland105
mouth30
muscle65
nerve64
ovary98
pancreas103
pharynx98
pituitary gland121
placenta56
prostate47
skin47
spleen37
stomach10
testis45
thymus12
umbilical cord72
uterus30
vascular38
Health State
TissuesTPM*
normal53
adrenal tumor79
bladder carcinoma113
breast (mammary gland) tumor150
cervical tumor86
chondrosarcoma96
colorectal tumor53
esophageal tumor57
gastrointestinal tumor8
germ cell tumor72
glioma93
head and neck tumor29
kidney tumor14
leukemia95
liver tumor52
lung tumor58
lymphoma55
non-neoplasia51
ovarian tumor78
pancreatic tumor38
primitive neuroectodermal tumor of the CNS94
prostate cancer67
retinoblastoma86
skin tumor47
soft tissue/muscle tissue tumor71
uterine tumor33
Developmental Stage
TissuesTPM*
adult48
embryoid body71
blastocyst32
neonate64
fetus80
infant170
juvenile71
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue58.4
adrenal gland48.8
appendix49.7
bone marrow47.1
cerebral cortex74.5
colon64.6
duodenum31.2
esophagus45.3
gallbladder37.6
heart muscle36.6
kidney64.9
liver48.1
lung39.2
lymph node57.5
ovary48.9
pancreas15.6
placenta48.3
prostate47
salivary gland31.4
skin38
small intestine39.8
spleen50.5
stomach50.7
testis31.3
thyroid gland44.2
urinary bladder47.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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