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> Protein (NX_Q96PE7)
Protein (NX_Q96PE7)
Protein
Gene SymbolMCEE to neXtProt (NX_Q96PE7)
DescriptionMethylmalonyl-CoA epimerase, mitochondrial
Chromosome2
Location2p13.3 (71336814 ~ 71357369) to Ensembl
Sequene Features : Isoforms 1, Variants 28, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.L-methylmalonyl-CoA metabolic process
.small molecule metabolic process
.cellular lipid metabolic process
  + 2 more...
.metal ion binding
.methylmalonyl-CoA epimerase activity
.mitochondrial matrix
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 28 3
2014-09-19protein level
1 22 3
2014-05-27protein level
1 22 3
2014-02-25protein level
1 22 1
2013-12-09protein level
1 17 1
2013-11-01protein level
1 17 1
2013-09-12protein level
1 17 0
2013-08-17protein level
1 17 0
2013-07-15protein level
1 13 0
2013-06-11protein level
1 13 0
2013-02-12protein level
1 8 1
2012-12-20protein level
1 8 1
2012-10-30protein level
1 9 1
2012-10-07protein level
1 9 1
2012-08-24protein level
1 7 1
2012-07-28protein level
1 7 1
2012-06-08protein level
1 7 1
2012-05-07protein level
1 7 1
2012-04-10protein level
1 7 1
2012-01-13protein level
1 4 1
2011-12-20protein level
1 4 1
2011-11-11protein level
1 4 1
2011-08-23protein level
1 4 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96PE7-1
10 0 0 18737.0131
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10292326,EBI-741181 AGTRAP  
  .regulation of blood pressure
.response to hypoxia
.angiotensin type II receptor activity .intracellular membrane-bounded organelle
.cytoplasmic vesicle membrane
.integral component of membrane
  + 6 more...
2 EBI-10292326,EBI-2548702 CMTM5  
  .negative regulation of myoblast differentiation
.chemotaxis
.N/A .integral component of membrane
.extracellular space
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
bone55
connective tissue20
ear124
embryonic tissue14
eye4
heart22
intestine17
kidney42
liver107
lung29
lymph node66
mammary gland19
muscle9
ovary9
pancreas37
parathyroid48
pharynx24
placenta60
prostate15
skin18
stomach10
testis2
thyroid42
uterus17
Health State
TissuesTPM*
normal26
chondrosarcoma36
gastrointestinal tumor8
germ cell tumor3
head and neck tumor14
leukemia10
liver tumor124
primitive neuroectodermal tumor of the CNS23
skin tumor15
soft tissue/muscle tissue tumor23
uterine tumor33
Developmental Stage
TissuesTPM*
adult26
blastocyst32
fetus21
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue15.3
adrenal gland25.8
appendix12.8
bone marrow6
cerebral cortex7.9
colon19.6
duodenum17.6
esophagus24.9
gallbladder14.7
heart muscle28.2
kidney27.8
liver29.6
lung12.9
lymph node13
ovary16.8
pancreas14.4
placenta16.9
prostate23.8
salivary gland29.5
skin21.3
small intestine15.1
spleen10.7
stomach19
testis7.3
thyroid gland13.3
urinary bladder20
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(#251120, phenotype) Methylmalonyl-coa epimerase deficiencyOMIM
2(*608419, gene) Methylmalonyl-coa epimerase; MCEEOMIM


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