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> Protein (NX_Q96PQ6)
Protein (NX_Q96PQ6)
Protein
Gene SymbolZNF317 to neXtProt (NX_Q96PQ6)
DescriptionZinc finger protein 317
Chromosome19
Location19p13.2 (9251056 ~ 9274100) to Ensembl
Sequene Features : Isoforms 4, Variants 78, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 78 0
2014-09-19protein level
4 60 0
2014-05-27transcript level
4 60 0
2014-02-25transcript level
4 60 0
2013-12-09transcript level
4 46 0
2013-11-01transcript level
4 43 0
2013-09-12transcript level
4 43 0
2013-08-17protein level
4 43 0
2013-07-15protein level
4 30 0
2013-06-11protein level
4 30 0
2013-02-12protein level
4 14 0
2012-12-20protein level
4 15 0
2012-10-30protein level
4 21 0
2012-10-07protein level
4 21 0
2012-08-24transcript level
4 20 0
2012-07-28transcript level
4 20 0
2012-06-08transcript level
4 21 0
2012-05-07transcript level
4 17 0
2012-04-10transcript level
4 17 0
2012-01-13transcript level
4 4 0
2011-12-20transcript level
4 4 0
2011-11-11transcript level
4 4 0
2011-08-23transcript level
4 4 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96PQ6-1
1 26 3 67914.8047
NX_Q96PQ6-2
1 25 3 64427.1607
NX_Q96PQ6-3
1 22 3 55094.802
NX_Q96PQ6-4
1 23 3 58582.446
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1210473,EBI-8638511 RBMY1A1  
  .RNA splicing
.mRNA processing
.regulation of alternative mRNA splicing, via spliceosome
.mRNA binding
.nucleotide binding
.nucleus
2 EBI-10292528,EBI-10172052 KRTAP10-9  
  .N/A .N/A .keratin filament
3 EBI-10292528,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
4 EBI-1210473,EBI-3920396 C11orf57  
  .N/A .N/A .N/A
5 EBI-1210473,EBI-8637627 AEN  
  .nucleic acid phosphodiester bond hydrolysis
.intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
.response to ionizing radiation
.exonuclease activity
.nucleic acid binding
.nuclear membrane
.nucleolus
.nucleoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
ascites25
bladder33
blood40
bone13
bone marrow82
brain76
connective tissue40
embryonic tissue46
esophagus99
eye43
intestine64
kidney28
larynx42
liver24
lung41
lymph67
lymph node66
mammary gland26
mouth136
muscle84
ovary59
pancreas9
parathyroid48
placenta21
prostate36
stomach10
testis66
thymus50
tonsil58
trachea115
umbilical cord290
uterus73
vascular77
Health State
TissuesTPM*
normal42
adrenal tumor79
breast (mammary gland) tumor21
chondrosarcoma24
colorectal tumor88
esophageal tumor115
gastrointestinal tumor25
germ cell tumor106
glioma46
head and neck tumor74
kidney tumor14
leukemia42
liver tumor31
lung tumor38
lymphoma41
non-neoplasia31
ovarian tumor65
pancreatic tumor19
primitive neuroectodermal tumor of the CNS39
prostate cancer57
retinoblastoma21
soft tissue/muscle tissue tumor95
uterine tumor11
Developmental Stage
TissuesTPM*
adult39
embryoid body71
blastocyst65
neonate96
fetus61
infant42
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue8.4
adrenal gland8.9
appendix11.7
bone marrow22.5
cerebral cortex9.5
colon10.6
duodenum11.2
esophagus10
gallbladder10.1
heart muscle6.4
kidney9.4
liver5.4
lung10.5
lymph node15.6
ovary12.5
pancreas6.9
placenta9.9
prostate9.1
salivary gland8.9
skin12.4
small intestine10.6
spleen13.4
stomach11.5
testis5.3
thyroid gland11.9
urinary bladder12.7
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*613864, gene) Zinc finger protein 317; ZNF317OMIM


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