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> Protein (NX_Q96PV4)
Protein (NX_Q96PV4)
Gene SymbolPNMA5 to neXtProt (NX_Q96PV4)
DescriptionParaneoplastic antigen-like protein 5
LocationXq28 (152157368 ~ 152162671) to Ensembl
Sequene Features : Isoforms 1, Variants 75, PTMsto neXtProt Sequence Features
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of apoptotic process .identical protein binding .N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 75 0
2014-09-19protein level
1 62 0
2014-05-27protein level
1 62 0
2014-02-25protein level
1 62 0
2013-12-09protein level
1 47 0
2013-11-01protein level
1 45 0
2013-09-12protein level
1 45 0
2013-08-17protein level
1 45 0
2013-07-15transcript level
1 25 0
2013-06-11transcript level
1 25 0
2013-02-12transcript level
1 12 0
2012-12-20transcript level
1 11 0
2012-10-30transcript level
1 16 0
2012-10-07transcript level
1 16 0
2012-08-24transcript level
1 14 0
2012-07-28transcript level
1 14 0
2012-06-08transcript level
1 14 0
2012-05-07transcript level
1 14 0
2012-04-10transcript level
1 14 0
2012-01-13transcript level
1 3 0
2011-12-20transcript level
1 3 0
2011-11-11transcript level
1 3 0
2011-08-23transcript level
1 3 0
Protein Isoforms
Isoform Ac UGSMw (Da)
20 0 0 49902.3551
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10171633,EBI-431907 TNPO2  
  .intracellular protein transport .nuclear localization sequence binding .cytoplasm
2 EBI-10171633,EBI-353844 VIM  
  .lens fiber cell development
.SMAD protein signal transduction
.Bergmann glial cell differentiation
  + 10 more...
.keratin filament binding
.scaffold protein binding
.identical protein binding
  + 5 more...
.extracellular exosome
.intermediate filament cytoskeleton
.neuron projection
  + 8 more...
3 EBI-10171633,EBI-739899 ZBTB25  
  .gene expression
.transcription from RNA polymerase II promoter
.regulation of transcription from RNA polymerase II promoter
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.RNA polymerase II regulatory region sequence-specific DNA binding
4 EBI-10171633,EBI-395261 CCNC  
  .positive regulation of transcription from RNA polymerase II promoter
.gene expression
.Notch signaling pathway
  + 4 more...
.N/A .mediator complex
5 EBI-10171633,EBI-359352 PSMA1  
  .positive regulation of canonical Wnt signaling pathway
.negative regulation of canonical Wnt signaling pathway
.regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
  + 23 more...
.threonine-type endopeptidase activity
.endopeptidase activity
.RNA binding
.extracellular exosome
.proteasome core complex, alpha-subunit complex
  + 7 more...
6 EBI-10171633,EBI-351257 DDX6  
  .exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
.cytoplasmic mRNA processing body assembly
.viral RNA genome packaging
  + 4 more...
.poly(A) RNA binding
.protein domain specific binding
.ATP binding
  + 3 more...
.intracellular membrane-bounded organelle
.RISC complex
  + 5 more...
7 EBI-10171633,EBI-1789926 CETN2  
  .cell division
.cellular protein metabolic process
.post-translational protein modification
  + 9 more...
.calcium ion binding .XPC complex
.ciliary basal body
.photoreceptor connecting cilium
  + 5 more...
8 EBI-10171633,EBI-954531 RAD23B  
  .proteasome-mediated ubiquitin-dependent protein catabolic process
.regulation of proteasomal ubiquitin-dependent protein catabolic process
  + 4 more...
.polyubiquitin binding
.single-stranded DNA binding
.damaged DNA binding
.XPC complex
  + 2 more...
9 EBI-10171633,EBI-351872 ARPC4  
  .ephrin receptor signaling pathway
.innate immune response
.actin nucleation
  + 5 more...
.enzyme binding
.structural constituent of cytoskeleton
.extracellular exosome
.cell projection
.Arp2/3 protein complex
10 EBI-10171633,EBI-401755 GRB2  
  .positive regulation of reactive oxygen species metabolic process
.cellular response to ionizing radiation
.branching involved in labyrinthine layer morphogenesis
  + 25 more...
.ephrin receptor binding
.poly(A) RNA binding
.insulin receptor substrate binding
  + 6 more...
.Grb2-EGFR complex
.extracellular exosome
.vesicle membrane
  + 10 more...
11 EBI-10171633,EBI-1181405 PRKAA1  
  .negative regulation of glucose import in response to insulin stimulus
.regulation of energy homeostasis
.response to camptothecin
  + 42 more...
.[acetyl-CoA carboxylase] kinase activity
.tau-protein kinase activity
.[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity
  + 7 more...
.AMP-activated protein kinase complex
.apical plasma membrane
  + 4 more...
12 EBI-10171633,EBI-6447954 TTC23  
  .N/A .N/A .N/A
13 EBI-10171633,EBI-1104570 CEP57L1  
  .microtubule anchoring .N/A .microtubule
.microtubule organizing center
14 EBI-10171633,EBI-302345 PNMA1  
  .positive regulation of apoptotic process
.inflammatory response to antigenic stimulus
.N/A .focal adhesion
15 EBI-10171633,EBI-739825 MOAP1  
  .extrinsic apoptotic signaling pathway in absence of ligand
.apoptotic signaling pathway
.positive regulation of release of cytochrome c from mitochondria
  + 4 more...
.ubiquitin protein ligase binding .cytosol
.mitochondrial outer membrane
16 EBI-10171633,EBI-746595 ZMYND19  
  .N/A .metal ion binding .synapse
.plasma membrane
17 EBI-10171633,EBI-741158 WDYHV1  
  .cellular protein modification process .protein-N-terminal glutamine amidohydrolase activity .cytosol
18 EBI-10171633,EBI-5452779 POLR3C  
  .defense response to virus
.positive regulation of innate immune response
.innate immune response
  + 7 more...
.DNA-directed RNA polymerase activity
.DNA binding
.DNA-directed RNA polymerase III complex
19 EBI-10171633,EBI-541426 AP1M1  
  .membrane organization
.regulation of defense response to virus by virus
.endosome to melanosome transport
  + 5 more...
.N/A .extracellular exosome
.trans-Golgi network membrane
.clathrin-coated endocytic vesicle membrane
  + 6 more...
20 EBI-10171633,EBI-751319 CARD9  
  .nucleotide-binding oligomerization domain containing signaling pathway
.defense response to virus
.defense response to Gram-positive bacterium
  + 17 more...
.CARD domain binding
.protein homodimerization activity
.plasma membrane
21 EBI-10171633,EBI-721300 C11orf49  
  .N/A .N/A .nucleoplasm
22 EBI-10171633,EBI-739467 GORASP2  
  .organelle organization
.mitotic cell cycle
.N/A .membrane
.Golgi apparatus
.Golgi membrane
23 EBI-10171633,EBI-8787464 TBC1D22B  
  .N/A .GTPase activator activity .N/A
24 EBI-10171633,EBI-10309345 TXNL4B  
  .mitotic nuclear division
.spliceosomal complex assembly
.N/A .U4/U6 x U5 tri-snRNP complex
.U5 snRNP
.spliceosomal complex
25 EBI-10171633,EBI-396137 CDC23  
  .protein K11-linked ubiquitination
.regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
.positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
  + 11 more...
.ubiquitin-protein transferase activity .cytosol
.anaphase-promoting complex
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
Health State
head and neck tumor7
primitive neuroectodermal tumor of the CNS7
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
cerebral cortex4.3
TissuesExpression level
skin 2Low
TumorNumber of patients and Staining levels
breast cancer
cervical cancer
colorectal cancer
endometrial cancer
head and neck cancer
liver cancer
lung cancer
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected

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