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> Protein (NX_Q96Q77)
Protein (NX_Q96Q77)
Protein
Gene SymbolCIB3 to neXtProt (NX_Q96Q77)
DescriptionCalcium and integrin-binding family member 3
Chromosome19
Location19p13.12 (16272179 ~ 16284336) to Ensembl
Sequene Features : Isoforms 2, Variants 44, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .calcium ion binding .N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 44 0
2014-09-19protein level
2 36 0
2014-05-27protein level
1 36 0
2014-02-25transcript level
1 36 0
2013-12-09transcript level
1 31 0
2013-11-01transcript level
1 31 0
2013-09-12transcript level
1 31 0
2013-08-17transcript level
1 31 0
2013-07-15transcript level
1 21 0
2013-06-11transcript level
1 21 0
2013-02-12transcript level
1 9 0
2012-12-20transcript level
1 9 0
2012-10-30transcript level
1 10 0
2012-10-07transcript level
1 10 0
2012-08-24transcript level
1 6 0
2012-07-28transcript level
1 6 0
2012-06-08transcript level
1 6 0
2012-05-07transcript level
1 6 0
2012-04-10transcript level
1 6 0
2012-01-13transcript level
1 3 0
2011-12-20transcript level
1 3 0
2011-11-11transcript level
1 3 0
2011-08-23transcript level
1 3 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96Q77-1
3 5 1 21787.4337
NX_Q96Q77-2
1 5 1 15963.5279
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10292696,EBI-2864512 MEOX1  
  .sclerotome development
.somite development
.hematopoietic stem cell differentiation
  + 2 more...
.sequence-specific DNA binding
.sequence-specific DNA binding transcription factor activity
.chromatin binding
  + 3 more...
.cytoplasm
.nucleus
2 EBI-10292696,EBI-10198587 SP4  
  .regulation of heart contraction
.transcription from RNA polymerase II promoter
.regulation of transcription from RNA polymerase II promoter
.metal ion binding
.transcription coactivator activity
.DNA binding
.sequence-specific DNA binding RNA polymerase II transcription factor activity
.intercellular bridge
.microtubule cytoskeleton
.cytoplasm
.nucleoplasm
3 EBI-10292696,EBI-307352 REL  
  .negative regulation of neuron death
.positive regulation of transcription from RNA polymerase II promoter
.innate immune response
  + 10 more...
.sequence-specific DNA binding transcription factor activity
.chromatin binding
.RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.RNA polymerase II distal enhancer sequence-specific DNA binding
.I-kappaB/NF-kappaB complex
.cytosol
.transcription factor complex
  + 2 more...
4 EBI-10292696,EBI-717810 AES  
  .positive regulation of anoikis
.negative regulation of canonical Wnt signaling pathway
.response to interleukin-1
  + 12 more...
.transcription corepressor activity .nucleus
5 EBI-10292696,EBI-10179508 ENOX2  
  .oxidation-reduction process
.regulation of growth
.cell growth
.ultradian rhythm
.protein disulfide oxidoreductase activity
.nucleic acid binding
.nucleotide binding
.external side of plasma membrane
.cytosol
.extracellular space
6 EBI-10292696,EBI-10292791 KLF17  
  .gamete generation
.regulation of transcription from RNA polymerase II promoter
.transcription, DNA-templated
.metal ion binding
.transcription regulatory region DNA binding
.sequence-specific DNA binding transcription factor activity
.nucleus
7 EBI-10292696,EBI-749265 CCDC155  
  .chromosome localization to nuclear envelope involved in homologous chromosome segregation
.oogenesis
.spermatogenesis
  + 2 more...
.N/A .integral component of membrane
.nuclear outer membrane
.lateral element
.chromosome, telomeric region
8 EBI-10292696,EBI-10181188 BEND7  
  .N/A .N/A .extracellular exosome
9 EBI-10292696,EBI-739832 LNX1  
  .protein homooligomerization
.protein ubiquitination involved in ubiquitin-dependent protein catabolic process
.ligase activity
.zinc ion binding
.ubiquitin-protein transferase activity
.cytoplasm
10 EBI-10292696,EBI-8643207 ZNF398  
  .positive regulation of transcription, DNA-templated
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
11 EBI-10292696,EBI-743265 ZNF426  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
12 EBI-10292696,EBI-749840 TRIM2  
  .regulation of neuron apoptotic process .ligase activity
.zinc ion binding
.ubiquitin-protein transferase activity
.cytoplasm
13 EBI-10292696,EBI-2554984 TACC3  
  .regulation of cell cycle
.cytoplasmic sequestering of transcription factor
.regulation of microtubule-based process
  + 8 more...
.N/A .centrosome
.cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
connective tissue26
Health State
TissuesTPM*
soft tissue/muscle tissue tumor31
Developmental Stage
TissuesTPM*
adult2
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*610645, gene) Calcium- and integrin-binding protein 3; CIB3OMIM


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