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> Protein (NX_Q96RL7)
Protein (NX_Q96RL7)
Protein
Gene SymbolVPS13A to neXtProt (NX_Q96RL7)
DescriptionVacuolar protein sorting-associated protein 13A
Chromosome9
Location9q21.2 (79792269 ~ 80036457) to Ensembl
Sequene Features : Isoforms 4, Variants 368, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.protein retention in Golgi apparatus
.social behavior
.protein localization
  + 4 more...
.N/A .dense core granule
.extrinsic component of membrane
.intracellular
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 368 4
2014-09-19protein level
4 280 4
2014-05-27protein level
4 280 4
2014-02-25protein level
4 277 4
2013-12-09protein level
4 219 4
2013-11-01protein level
4 210 1
2013-09-12protein level
4 210 2
2013-08-17protein level
4 210 2
2013-07-15protein level
4 144 2
2013-06-11protein level
4 144 2
2013-02-12protein level
4 63 8
2012-12-20protein level
4 62 8
2012-10-30protein level
4 80 8
2012-10-07protein level
4 80 2
2012-08-24protein level
4 75 2
2012-07-28protein level
4 74 2
2012-06-08protein level
4 84 2
2012-05-07protein level
4 63 2
2012-04-10protein level
4 63 2
2012-01-13protein level
4 42 2
2011-12-20protein level
4 42 2
2011-11-11protein level
4 42 2
2011-08-23protein level
4 42 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96RL7-1
0 139 0 360046.4252
NX_Q96RL7-2
2 134 0 350679.0708
NX_Q96RL7-3
1 137 0 355634.0792
NX_Q96RL7-4
1 134 0 347451.9344
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1752583,EBI-389883 NCK1  
  .negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
.negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
.negative regulation of PERK-mediated unfolded protein response
  + 23 more...
.eukaryotic initiation factor eIF2 binding
.receptor tyrosine kinase binding
.protein binding, bridging
  + 5 more...
.vesicle membrane
.cell-cell junction
.plasma membrane
  + 6 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue233
adrenal gland30
ascites50
blood16
bone27
brain15
connective tissue40
embryonic tissue46
eye23
intestine17
kidney61
liver24
lung41
lymph22
lymph node11
mammary gland59
muscle56
ovary9
pancreas23
parathyroid48
placenta10
prostate68
skin9
spleen56
stomach20
testis13
thymus25
thyroid21
trachea57
umbilical cord72
uterus17
vascular19
Health State
TissuesTPM*
normal2
adrenal tumor79
breast (mammary gland) tumor32
chondrosarcoma36
colorectal tumor26
gastrointestinal tumor33
germ cell tumor15
head and neck tumor7
kidney tumor14
leukemia21
liver tumor20
lung tumor29
lymphoma13
primitive neuroectodermal tumor of the CNS15
prostate cancer67
skin tumor7
soft tissue/muscle tissue tumor47
uterine tumor33
Developmental Stage
TissuesTPM*
adult34
embryoid body14
blastocyst65
neonate32
fetus5
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue6
adrenal gland12.9
appendix10.7
bone marrow13.9
cerebral cortex5.9
colon14.8
duodenum26.5
esophagus8.5
gallbladder15.4
heart muscle9.9
kidney13.3
liver5.3
lung10.8
lymph node13.6
ovary4.6
pancreas6.3
placenta4
prostate12.4
salivary gland8.5
skin28.6
small intestine21.5
spleen15.2
stomach17.3
testis19
thyroid gland11.7
urinary bladder11.5
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowLow
breastMedium
bronchusMedium
cerebellumLow
cerebral cortexLow
cervix, uterineLow
colonMedium
duodenumMedium
endometrium 1Low
endometrium 2Medium
epididymisMedium
esophagusLow
fallopian tubeLow
gallbladderMedium
heart muscleMedium
hippocampusMedium
kidneyHigh
lateral ventricleLow
liverMedium
lungMedium
lymph nodeMedium
nasopharynxMedium
pancreasMedium
parathyroid glandMedium
placentaLow
prostateMedium
rectumMedium
salivary glandLow
seminal vesicleLow
skin 1Medium
skin 2Low
small intestineMedium
soft tissue 1Medium
soft tissue 2Medium
spleenMedium
stomach 1Medium
stomach 2Medium
testisHigh
thyroid glandLow
tonsilMedium
urinary bladderMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(#200150, phenotype) Choreoacanthocytosis; CHACOMIM
2(*605978, gene) Vacuolar protein sorting 13, yeast, homolog of, a; VPS13AOMIM


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