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> Protein (NX_Q96RP9)
Protein (NX_Q96RP9)
Protein
Gene SymbolGFM1 to neXtProt (NX_Q96RP9)
DescriptionElongation factor G, mitochondrial
Chromosome3
Location3q25.32 (158362067 ~ 158410364) to Ensembl
Sequene Features : Isoforms 2, Variants 91, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.mitochondrial translational elongation
.mitochondrial translation
.organelle organization
.poly(A) RNA binding
.GTP binding
.GTPase activity
.translation elongation factor activity
.mitochondrial matrix
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 91 3
2014-09-19protein level
2 77 3
2014-05-27protein level
2 77 3
2014-02-25protein level
2 74 3
2013-12-09protein level
2 57 3
2013-11-01protein level
2 56 2
2013-09-12protein level
2 56 2
2013-08-17protein level
2 56 2
2013-07-15protein level
2 33 1
2013-06-11protein level
2 33 1
2013-02-12protein level
2 21 2
2012-12-20protein level
2 19 2
2012-10-30protein level
2 24 2
2012-10-07protein level
2 24 1
2012-08-24protein level
2 24 1
2012-07-28protein level
2 24 1
2012-06-08protein level
2 26 1
2012-05-07protein level
2 21 1
2012-04-10protein level
2 21 1
2012-01-13protein level
2 17 1
2011-12-20protein level
2 17 1
2011-11-11protein level
2 17 1
2011-08-23protein level
2 17 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96RP9-1
1 36 0 83418.2049
NX_Q96RP9-2
2 36 0 85814.4271
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2255048,EBI-5661333 TRIM63  
  .cellular response to dexamethasone stimulus
.response to interleukin-1
.proteasome-mediated ubiquitin-dependent protein catabolic process
  + 5 more...
.titin binding
.ligase activity
.zinc ion binding
  + 2 more...
.M band
.Z disc
.microtubule
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
ascites150
bladder167
blood98
bone83
bone marrow143
brain140
cervix82
connective tissue53
ear62
embryonic tissue37
esophagus99
eye28
heart55
intestine25
kidney142
larynx42
liver43
lung44
lymph node122
mammary gland39
mouth377
muscle47
nerve193
ovary9
pancreas32
parathyroid48
pituitary gland121
placenta67
prostate31
salivary gland49
skin85
spleen56
stomach31
testis163
thymus87
thyroid21
trachea424
uterus56
vascular96
Health State
TissuesTPM*
normal88
bladder carcinoma56
breast (mammary gland) tumor42
chondrosarcoma108
colorectal tumor8
esophageal tumor115
gastrointestinal tumor75
germ cell tumor79
glioma27
head and neck tumor186
kidney tumor58
leukemia52
liver tumor41
lung tumor19
lymphoma69
non-neoplasia62
ovarian tumor13
pancreatic tumor9
primitive neuroectodermal tumor of the CNS15
prostate cancer19
skin tumor87
uterine tumor33
Developmental Stage
TissuesTPM*
adult53
embryoid body42
blastocyst48
neonate160
fetus70
infant42
juvenile143
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue27.2
adrenal gland29.9
appendix25.3
bone marrow13.8
cerebral cortex20.8
colon30.4
duodenum28.1
esophagus21.8
gallbladder20.3
heart muscle32.4
kidney39.7
liver25.8
lung17.8
lymph node21.1
ovary13.5
pancreas10.4
placenta21.1
prostate25.1
salivary gland15.6
skin13.8
small intestine21.7
spleen16.6
stomach22.4
testis26.4
thyroid gland30.8
urinary bladder23.9
Tissues
TissuesExpression level
adrenal glandHigh
appendixMedium
bone marrowMedium
breastHigh
bronchusHigh
cerebellumMedium
cerebral cortexMedium
cervix, uterineMedium
colonHigh
duodenumMedium
endometrium 1Medium
endometrium 2Low
epididymisHigh
esophagusMedium
fallopian tubeLow
gallbladderHigh
heart muscleMedium
hippocampusMedium
kidneyHigh
lateral ventricleMedium
liverMedium
lungHigh
lymph nodeHigh
nasopharynxMedium
oral mucosaLow
ovaryLow
pancreasHigh
parathyroid glandHigh
placentaHigh
prostateLow
rectumHigh
salivary glandMedium
seminal vesicleMedium
skeletal muscleMedium
skin 1High
skin 2Medium
small intestineHigh
smooth muscleMedium
soft tissue 1Low
soft tissue 2Medium
stomach 1Medium
stomach 2High
testisHigh
thyroid glandMedium
tonsilMedium
urinary bladderMedium
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*606639, gene) Mitochondrial elongation factor g1; GFM1OMIM
2(#609060, phenotype) Combined oxidative phosphorylation deficiency 1; COXPD1OMIM


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