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> Protein (NX_Q96S65)
Protein (NX_Q96S65)
Protein
Gene SymbolCSRNP1 to neXtProt (NX_Q96S65)
DescriptionCysteine/serine-rich nuclear protein 1
Chromosome3
Location3p22.2 (39183346 ~ 39196053) to Ensembl
Sequene Features : Isoforms 1, Variants 76, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.face morphogenesis
.palate development
.skeletal system morphogenesis
  + 4 more...
.sequence-specific DNA binding
.sequence-specific DNA binding transcription factor activity
.RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 76 2
2014-09-19protein level
1 66 2
2014-05-27protein level
1 66 2
2014-02-25protein level
1 66 2
2013-12-09protein level
1 50 2
2013-11-01protein level
1 48 2
2013-09-12protein level
1 48 2
2013-08-17protein level
1 48 2
2013-07-15protein level
1 35 1
2013-06-11protein level
1 35 1
2013-02-12transcript level
1 19 0
2012-12-20transcript level
1 19 0
2012-10-30transcript level
1 24 0
2012-10-07transcript level
1 24 0
2012-08-24transcript level
1 17 0
2012-07-28transcript level
1 17 0
2012-06-08transcript level
1 17 0
2012-05-07transcript level
1 17 0
2012-04-10transcript level
1 17 0
2012-01-13transcript level
1 6 0
2011-12-20transcript level
1 6 0
2011-11-11transcript level
1 6 0
2011-08-23transcript level
1 6 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96S65-1
21 0 0 63467.7477
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-4311573,EBI-745213 AQP1  
  .cation transmembrane transport
.maintenance of symbiont-containing vacuole by host
.ammonium transmembrane transport
  + 60 more...
.carbon dioxide transmembrane transporter activity
.nitric oxide transmembrane transporter activity
.transmembrane transporter activity
  + 8 more...
.extracellular exosome
.apical part of cell
.axon terminus
  + 12 more...
2 EBI-4311573,EBI-356283 PPP1CC  
  .cell division
.small molecule metabolic process
.entrainment of circadian clock by photoperiod
  + 10 more...
.protein N-terminus binding
.metal ion binding
.poly(A) RNA binding
  + 4 more...
.PTW/PP1 phosphatase complex
.MLL5-L complex
.protein complex
  + 11 more...
3 EBI-4311573,EBI-357253 PPP1CA  
  .positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
.cell division
.branching morphogenesis of an epithelial tube
  + 15 more...
.metal ion binding
.ribonucleoprotein complex binding
.phosphatase activity
.protein serine/threonine phosphatase activity
.PTW/PP1 phosphatase complex
.MLL5-L complex
.extracellular exosome
  + 10 more...
4 EBI-4311573,EBI-954696 TCEANC  
  .regulation of DNA-templated transcription, elongation
.regulation of transcription from RNA polymerase II promoter
.transcription, DNA-templated
.DNA binding .nucleus
5 EBI-4311573,EBI-740727 ZNF417  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
6 EBI-4311573,EBI-6427977 ZNF587  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
ascites25
blood57
bone97
brain10
connective tissue60
embryonic tissue37
eye23
heart11
intestine17
lung47
lymph node22
mammary gland33
muscle18
ovary39
pancreas37
placenta70
prostate36
skin9
stomach94
testis6
thyroid42
umbilical cord72
uterus17
vascular19
Health State
TissuesTPM*
normal34
breast (mammary gland) tumor32
chondrosarcoma181
colorectal tumor26
gastrointestinal tumor16
germ cell tumor18
glioma27
head and neck tumor7
leukemia10
lung tumor9
non-neoplasia20
ovarian tumor26
pancreatic tumor9
prostate cancer19
skin tumor15
soft tissue/muscle tissue tumor7
uterine tumor22
Developmental Stage
TissuesTPM*
adult64
embryoid body57
blastocyst65
neonate32
fetus14
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue62.2
adrenal gland50
appendix29.9
bone marrow109
cerebral cortex11.1
colon19.2
duodenum9.7
esophagus57
gallbladder68.6
heart muscle13.4
kidney12.2
liver26.8
lung31.8
lymph node13.7
ovary25.9
pancreas18.5
placenta22.8
prostate23.5
salivary gland11.5
skin4.6
small intestine16.7
spleen15.7
stomach13.1
testis9.4
thyroid gland31.9
urinary bladder37.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*606458, gene) Axin1 upregulated; AXUD1OMIM


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