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> Protein (NX_Q96S94)
Protein (NX_Q96S94)
Protein
Gene SymbolCCNL2 to neXtProt (NX_Q96S94)
DescriptionCyclin-L2
Chromosome1
Location1p36.33 (1321091 ~ 1334708) to Ensembl
Sequene Features : Isoforms 3, Variants 58, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.regulation of cyclin-dependent protein serine/threonine kinase activity
.N/A .intracellular membrane-bounded organelle
.cell junction
.nuclear speck
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 58 8
2014-09-19protein level
3 46 8
2014-05-27protein level
3 46 10
2014-02-25protein level
3 45 10
2013-12-09protein level
3 37 10
2013-11-01protein level
3 36 10
2013-09-12protein level
3 36 9
2013-08-17protein level
3 36 9
2013-07-15protein level
3 25 9
2013-06-11protein level
3 25 9
2013-02-12protein level
3 12 22
2012-12-20protein level
3 9 22
2012-10-30protein level
3 15 22
2012-10-07protein level
3 15 11
2012-08-24protein level
3 13 11
2012-07-28protein level
3 13 11
2012-06-08protein level
3 16 11
2012-05-07protein level
3 16 11
2012-04-10protein level
3 16 11
2012-01-13protein level
3 8 11
2011-12-20protein level
3 8 11
2011-11-11protein level
3 8 10
2011-08-23protein level
3 8 10
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96S94-1
1 15 2 58111.3012
NX_Q96S94-2
1 8 2 24604.9018
NX_Q96S94-3
0 7 0 33818.5992
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1045974,EBI-747225 RUNDC3A  
  .small GTPase mediated signal transduction .GTPase regulator activity
.guanylate cyclase activator activity
.plasma membrane
.cytosol
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland212
ascites175
bladder66
blood130
bone139
bone marrow82
brain139
connective tissue114
embryonic tissue333
esophagus396
eye119
heart145
intestine168
kidney47
larynx127
liver131
lung131
lymph node122
mammary gland52
mouth256
muscle28
nerve128
ovary137
pancreas135
parathyroid145
pharynx417
pituitary gland181
placenta127
prostate485
salivary gland98
skin109
spleen206
stomach219
testis117
thymus301
thyroid107
trachea193
umbilical cord72
uterus284
vascular19
Health State
TissuesTPM*
normal150
adrenal tumor237
bladder carcinoma284
breast (mammary gland) tumor32
chondrosarcoma132
colorectal tumor124
esophageal tumor347
gastrointestinal tumor210
germ cell tumor79
glioma111
head and neck tumor276
kidney tumor72
leukemia158
liver tumor135
lung tumor145
lymphoma41
non-neoplasia82
ovarian tumor170
pancreatic tumor180
primitive neuroectodermal tumor of the CNS31
prostate cancer625
retinoblastoma43
skin tumor31
soft tissue/muscle tissue tumor23
uterine tumor310
Developmental Stage
TissuesTPM*
adult187
embryoid body271
blastocyst244
neonate96
fetus163
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue81.2
adrenal gland113.1
appendix96.4
bone marrow82.1
cerebral cortex39.6
colon56.9
duodenum106
esophagus67.3
gallbladder124
heart muscle59.2
kidney55.7
liver42
lung121
lymph node117.7
ovary130.7
pancreas60.2
placenta96
prostate119
salivary gland89.5
skin171.8
small intestine101.3
spleen121.4
stomach93.2
testis56.1
thyroid gland85.2
urinary bladder100.2
Tissues
TissuesExpression level
adrenal glandMedium
appendixHigh
bone marrowMedium
breastMedium
bronchusMedium
cerebellumMedium
cerebral cortexMedium
cervix, uterineMedium
colonHigh
duodenumHigh
endometrium 1Medium
endometrium 2Medium
epididymisMedium
esophagusHigh
fallopian tubeMedium
gallbladderMedium
heart muscleMedium
hippocampusHigh
kidneyMedium
lateral ventricleMedium
liverMedium
lungMedium
lymph nodeMedium
nasopharynxMedium
oral mucosaMedium
ovaryMedium
pancreasHigh
parathyroid glandMedium
placentaMedium
prostateMedium
rectumHigh
salivary glandMedium
seminal vesicleMedium
skeletal muscleMedium
skin 1Medium
skin 2High
small intestineHigh
smooth muscleMedium
soft tissue 1Medium
spleenMedium
stomach 1High
stomach 2High
testisMedium
thyroid glandMedium
tonsilHigh
urinary bladderMedium
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*613482, gene) Cyclin l2; CCNL2OMIM


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