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> Protein (NX_Q96TC7)
Protein (NX_Q96TC7)
Protein
Gene SymbolRMDN3 to neXtProt (NX_Q96TC7)
DescriptionRegulator of microtubule dynamics protein 3
Chromosome15
Location15q15.1 (41028082 ~ 41048049) to Ensembl
Sequene Features : Isoforms 2, Variants 22, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cell differentiation
.apoptotic process
.cellular calcium ion homeostasis
.N/A .integral component of membrane
.microtubule
.mitochondrial outer membrane
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 22 6
2014-09-19protein level
2 34 6
2014-05-27protein level
2 34 8
2014-02-25protein level
2 34 8
2013-12-09protein level
2 17 8
2013-11-01protein level
2 17 8
2013-09-12protein level
2 17 8
2013-08-17protein level
2 17 8
2013-07-15protein level
2 13 8
2013-06-11protein level
2 13 8
2013-02-12protein level
2 7 9
2012-12-20protein level
2 6 9
2012-10-30protein level
2 11 9
2012-10-07protein level
2 11 7
2012-08-24protein level
2 8 7
2012-07-28protein level
2 8 7
2012-06-08protein level
2 10 7
2012-05-07protein level
2 10 7
2012-04-10protein level
2 10 7
2012-01-13protein level
2 6 7
2011-12-20protein level
2 6 7
2011-11-11protein level
2 6 5
2011-08-23protein level
2 6 5
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q96TC7-1
7 14 0 52085.8894
NX_Q96TC7-2
0 14 0 38223.5289
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1056589,EBI-968788 PTPN1  
  .positive regulation of receptor catabolic process
.peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity
.negative regulation of PERK-mediated unfolded protein response
  + 25 more...
.ephrin receptor binding
.poly(A) RNA binding
.receptor tyrosine kinase binding
  + 4 more...
.cytoplasmic side of endoplasmic reticulum membrane
.sorting endosome
.cytoplasmic vesicle
  + 3 more...
2 EBI-1056589,EBI-359815 YWHAB  
  .positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
.intrinsic apoptotic signaling pathway
.membrane organization
  + 24 more...
.phosphoprotein binding
.phosphoserine binding
.histone deacetylase binding
  + 3 more...
.extracellular exosome
.perinuclear region of cytoplasm
.melanosome
  + 7 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland182
ascites50
bladder66
blood106
bone13
bone marrow20
brain194
cervix164
connective tissue60
embryonic tissue46
eye38
heart100
intestine81
kidney156
liver58
lung107
lymph45
lymph node11
mammary gland79
mouth60
muscle235
ovary216
pancreas107
parathyroid48
placenta70
prostate84
salivary gland394
skin75
spleen149
stomach62
testis34
thymus75
tonsil58
trachea96
umbilical cord72
uterus51
vascular116
Health State
TissuesTPM*
normal101
adrenal tumor158
breast (mammary gland) tumor107
cervical tumor115
chondrosarcoma12
colorectal tumor26
gastrointestinal tumor50
germ cell tumor79
glioma130
head and neck tumor67
kidney tumor188
leukemia127
liver tumor72
lung tumor48
lymphoma55
non-neoplasia155
ovarian tumor170
pancreatic tumor209
primitive neuroectodermal tumor of the CNS259
prostate cancer125
retinoblastoma86
skin tumor79
soft tissue/muscle tissue tumor31
uterine tumor44
Developmental Stage
TissuesTPM*
adult74
embryoid body57
blastocyst32
neonate225
fetus66
infant127
juvenile233
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue25.4
adrenal gland19.2
appendix16.2
bone marrow15.8
cerebral cortex30.2
colon19.3
duodenum45.2
esophagus16.2
gallbladder17.2
heart muscle11.3
kidney27.8
liver24.6
lung35
lymph node15.3
ovary15.1
pancreas12.3
placenta21.9
prostate20
salivary gland22.3
skin16.5
small intestine53
spleen15.8
stomach18.3
testis17.4
thyroid gland22.4
urinary bladder18.1
Tissues
TissuesExpression level
adrenal glandHigh
appendixHigh
bone marrowMedium
breastHigh
bronchusHigh
cerebellumHigh
cerebral cortexHigh
cervix, uterineHigh
colonHigh
duodenumHigh
endometrium 1High
endometrium 2High
epididymisHigh
esophagusHigh
fallopian tubeHigh
gallbladderHigh
heart muscleMedium
hippocampusHigh
kidneyHigh
lateral ventricleLow
liverMedium
lungHigh
lymph nodeLow
nasopharynxHigh
oral mucosaHigh
ovaryHigh
pancreasHigh
parathyroid glandMedium
placentaHigh
prostateHigh
rectumHigh
salivary glandHigh
seminal vesicleHigh
skin 1High
skin 2High
small intestineHigh
smooth muscleLow
soft tissue 1High
soft tissue 2High
spleenLow
stomach 1High
stomach 2High
testisHigh
thyroid glandHigh
tonsilHigh
urinary bladderHigh
vaginaHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*611873, gene) Family with sequence similarity 82, member a2; FAM82A2OMIM


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