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> Protein (NX_Q99638)
Protein (NX_Q99638)
Protein
Gene SymbolRAD9A to neXtProt (NX_Q99638)
DescriptionCell cycle checkpoint control protein RAD9A
Chromosome11
Location11q13.2 (67159176 ~ 67165881) to Ensembl
Sequene Features : Isoforms 1, Variants 41, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
.nucleic acid phosphodiester bond hydrolysis
.cellular response to ionizing radiation
  + 6 more...
.histone deacetylase binding
.protein kinase binding
.enzyme binding
  + 3 more...
.checkpoint clamp complex
.cytoplasm
.nucleoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 41 9
2014-09-19protein level
1 34 9
2014-05-27protein level
1 34 9
2014-02-25protein level
1 34 9
2013-12-09protein level
1 24 9
2013-11-01protein level
1 24 9
2013-09-12protein level
1 24 9
2013-08-17protein level
1 24 9
2013-07-15protein level
1 21 9
2013-06-11protein level
1 21 9
2013-02-12protein level
1 17 8
2012-12-20protein level
1 16 8
2012-10-30protein level
1 18 8
2012-10-07protein level
1 18 8
2012-08-24protein level
1 18 8
2012-07-28protein level
1 17 8
2012-06-08protein level
1 27 8
2012-05-07protein level
1 26 8
2012-04-10protein level
1 26 8
2012-01-13protein level
1 16 8
2011-12-20protein level
1 16 8
2011-11-11protein level
1 16 8
2011-08-23protein level
1 16 8
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q99638-1
16 0 0 42520.2373
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2606224,EBI-721835 RAD1  
  .nucleic acid phosphodiester bond hydrolysis
.cellular response to ionizing radiation
.meiotic recombination checkpoint
  + 5 more...
.exodeoxyribonuclease III activity
.3'-5' exonuclease activity
.damaged DNA binding
.intracellular membrane-bounded organelle
.checkpoint clamp complex
.chromosome
  + 2 more...
2 EBI-2606224,EBI-1056174 HUS1  
  .cellular response to ionizing radiation
.meiotic DNA integrity checkpoint
.mitotic DNA replication checkpoint
  + 12 more...
.N/A .site of double-strand break
.checkpoint clamp complex
.cytoplasm
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood8
brain5
cervix20
connective tissue20
embryonic tissue23
eye9
heart11
intestine47
kidney14
larynx42
liver4
lung11
lymph112
lymph node33
mammary gland39
mouth30
muscle47
ovary78
placenta3
prostate36
skin4
spleen18
testis9
thymus37
thyroid42
trachea19
uterus17
Health State
TissuesTPM*
normal9
breast (mammary gland) tumor64
cervical tumor28
chondrosarcoma24
colorectal tumor44
gastrointestinal tumor25
germ cell tumor15
head and neck tumor37
kidney tumor14
lung tumor9
lymphoma69
ovarian tumor78
primitive neuroectodermal tumor of the CNS110
prostate cancer67
retinoblastoma21
soft tissue/muscle tissue tumor23
uterine tumor33
Developmental Stage
TissuesTPM*
adult20
embryoid body28
blastocyst32
fetus8
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue5.3
adrenal gland6.6
appendix12
bone marrow12.7
cerebral cortex4.9
colon8.6
duodenum16.1
esophagus7
gallbladder10
heart muscle4.3
kidney7.3
liver4.5
lung11.7
lymph node18
ovary8.2
pancreas4.7
placenta9.2
prostate11.6
salivary gland9.1
skin22.3
small intestine15.9
spleen17.6
stomach13.6
testis10
thyroid gland10.4
urinary bladder8.8
Tissues
TissuesExpression level
adrenal glandHigh
appendixHigh
bone marrowHigh
breastHigh
bronchusMedium
cerebellumMedium
cerebral cortexMedium
cervix, uterineHigh
colonHigh
duodenumHigh
endometrium 1High
endometrium 2High
epididymisHigh
esophagusMedium
fallopian tubeHigh
gallbladderHigh
heart muscleLow
hippocampusLow
kidneyHigh
lateral ventricleLow
liverLow
lungHigh
lymph nodeHigh
nasopharynxMedium
oral mucosaHigh
ovaryLow
pancreasHigh
placentaHigh
prostateHigh
rectumHigh
salivary glandMedium
seminal vesicleHigh
skin 1High
skin 2High
small intestineHigh
smooth muscleMedium
soft tissue 1Medium
soft tissue 2Medium
spleenMedium
stomach 1High
stomach 2High
testisHigh
thyroid glandMedium
tonsilHigh
urinary bladderHigh
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603761, gene) Rad9, s. pombe, homolog of, a; RAD9AOMIM


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