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> Protein (NX_Q99689)
Protein (NX_Q99689)
Protein
Gene SymbolFEZ1 to neXtProt (NX_Q99689)
DescriptionFasciculation and elongation protein zeta-1
Chromosome11
Location11q24.2 (125315646 ~ 125366213) to Ensembl
Sequene Features : Isoforms 2, Variants 61, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cellular response to growth factor stimulus
.establishment of mitochondrion localization
.positive regulation of neuron projection development
  + 4 more...
.N/A .dendrite
.axon
.microtubule cytoskeleton
  + 5 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 61 2
2014-09-19protein level
2 48 2
2014-05-27protein level
2 48 2
2014-02-25protein level
2 47 2
2013-12-09protein level
2 32 2
2013-11-01protein level
2 32 2
2013-09-12protein level
2 32 3
2013-08-17protein level
2 32 3
2013-07-15protein level
2 19 3
2013-06-11protein level
2 19 3
2013-02-12protein level
2 6 4
2012-12-20protein level
2 6 4
2012-10-30protein level
2 7 4
2012-10-07protein level
2 7 3
2012-08-24protein level
2 4 3
2012-07-28protein level
2 4 3
2012-06-08protein level
2 5 3
2012-05-07protein level
2 3 3
2012-04-10protein level
2 3 3
2012-01-13protein level
2 4 3
2011-12-20protein level
2 4 3
2011-11-11protein level
2 4 3
2011-08-23protein level
2 4 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q99689-1
13 3 0 45090.5058
NX_Q99689-2
1 3 0 12066.4957
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-396435,EBI-707554 TXNDC9  
  .cell redox homeostasis .N/A .midbody
.centrosome
.cytoplasm
.nucleus
2 EBI-396435,EBI-466029 HTT  
  .negative regulation of extrinsic apoptotic signaling pathway
.iron ion homeostasis
.L-glutamate import
  + 38 more...
.diazepam binding
.beta-tubulin binding
.dynein intermediate chain binding
  + 6 more...
.protein complex
.cytoplasmic vesicle membrane
.dendrite
  + 11 more...
3 EBI-396435,EBI-373615 NEK1  
  .cell division
.cilium assembly
.response to ionizing radiation
  + 5 more...
.metal ion binding
.kinase activity
.ATP binding
  + 4 more...
.centrosome
.cytoplasm
.nucleus
.pericentriolar material
4 EBI-396435,EBI-473176 KIAA1377  
  .cilium assembly
.cytoplasmic microtubule organization
.mitotic spindle organization
.N/A .ciliary base
.midbody
.centrosome
.cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood8
bone marrow61
brain134
connective tissue33
embryonic tissue18
eye90
heart67
intestine12
kidney4
lung2
mouth15
pharynx24
placenta3
skin9
testis11
umbilical cord72
Health State
TissuesTPM*
normal14
chondrosarcoma48
colorectal tumor26
gastrointestinal tumor8
germ cell tumor15
glioma139
head and neck tumor7
kidney tumor14
lung tumor9
non-neoplasia20
skin tumor7
Developmental Stage
TissuesTPM*
adult6
embryoid body14
blastocyst16
neonate32
fetus80
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue12.6
adrenal gland13.1
appendix11
bone marrow2
cerebral cortex224.9
colon12.6
duodenum4.3
esophagus11
gallbladder28.1
heart muscle44.3
kidney4.7
liver9.5
lung23.9
lymph node11.1
ovary20.6
placenta14.9
prostate13.3
salivary gland2.9
skin7.6
small intestine6.8
spleen16.9
stomach4.1
testis22.9
thyroid gland3.7
urinary bladder40.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*604825, gene) Fasciculation and elongation protein zeta 1; FEZ1OMIM


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