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> Protein (NX_Q99750)
Protein (NX_Q99750)
Protein
Gene SymbolMDFI to neXtProt (NX_Q99750)
DescriptionMyoD family inhibitor
Chromosome6
Location6p21.1 (41604620 ~ 41621984) to Ensembl
Sequene Features : Isoforms 1, Variants 31, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.trophoblast giant cell differentiation
.embryonic skeletal system morphogenesis
.negative regulation of DNA binding
  + 6 more...
.N/A .cytoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 31 0
2014-09-19protein level
1 23 0
2014-05-27protein level
1 23 0
2014-02-25protein level
1 22 0
2013-12-09protein level
1 16 0
2013-11-01protein level
1 11 0
2013-09-12protein level
1 11 0
2013-08-17protein level
1 11 0
2013-07-15protein level
1 8 0
2013-06-11protein level
1 8 0
2013-02-12protein level
1 8 0
2012-12-20protein level
1 8 0
2012-10-30protein level
1 7 0
2012-10-07protein level
1 7 0
2012-08-24protein level
1 7 0
2012-07-28protein level
1 7 0
2012-06-08protein level
1 7 0
2012-05-07protein level
1 4 0
2012-04-10protein level
1 4 0
2012-01-13protein level
1 2 0
2011-12-20protein level
1 2 0
2011-11-11protein level
1 2 0
2011-08-23protein level
1 2 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q99750-1
4 0 0 25012.0277
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-724076,EBI-10171684 C14orf182  
  .N/A .N/A .N/A
2 EBI-724076,EBI-308663 ARHGAP32  
  .regulation of small GTPase mediated signal transduction
.small GTPase mediated signal transduction
.phosphatidylinositol binding
.GTPase activator activity
.postsynaptic membrane
.dendritic spine
.cell junction
  + 7 more...
3 EBI-724076,EBI-745608 ZNF646  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
4 EBI-724076,EBI-744471 ZBTB24  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.hematopoietic progenitor cell differentiation
.metal ion binding
.DNA binding
.nucleus
5 EBI-724076,EBI-748628 CBFA2T2  
  .positive regulation of transcription from RNA polymerase II promoter
.negative regulation of transcription, DNA-templated
.epithelial cell differentiation
  + 2 more...
.metal ion binding
.transcription corepressor activity
.sequence-specific DNA binding transcription factor activity
.nucleus
6 EBI-724076,EBI-742487 SPRY2  
  .positive regulation of protein serine/threonine kinase activity
.positive regulation of ERK1 and ERK2 cascade
.negative regulation of ERK1 and ERK2 cascade
  + 19 more...
.protein serine/threonine kinase activator activity
.protein serine/threonine kinase inhibitor activity
.protein kinase binding
.ruffle membrane
.microtubule cytoskeleton
.plasma membrane
  + 2 more...
7 EBI-724076,EBI-3866665 SPRY1  
  .negative regulation of ERK1 and ERK2 cascade
.bud elongation involved in lung branching
.negative regulation of neurotrophin TRK receptor signaling pathway
  + 10 more...
.N/A .plasma membrane
.cytosol
8 EBI-724076,EBI-1053424 PRKAB2  
  .membrane organization
.regulation of protein kinase activity
.small molecule metabolic process
  + 13 more...
.identical protein binding .AMP-activated protein kinase complex
.cytosol
.nucleoplasm
9 EBI-724076,EBI-947402 MAPKBP1  
  .N/A .N/A .N/A
10 EBI-724076,EBI-718707 LRCH4  
  .nervous system development .N/A .PML body
11 EBI-724076,EBI-1052725 TUSC2  
  .regulation of reactive oxygen species metabolic process
.chemokine (C-C motif) ligand 5 production
.neutrophil mediated killing of gram-negative bacterium
  + 12 more...
.N/A .mitochondrion
12 EBI-724076,EBI-742864 DKK1  
  .negative regulation of cardiac muscle cell differentiation
.negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment
.extracellular negative regulation of signal transduction
  + 21 more...
.low-density lipoprotein particle receptor binding
.receptor antagonist activity
.growth factor activity
.signal transducer activity
.early endosome membrane
.plasma membrane
.extracellular space
.extracellular region
13 EBI-724076,EBI-8058160 WNT11  
  .negative regulation of fibroblast growth factor production
.negative regulation of canonical Wnt signaling pathway
.positive regulation of protein kinase C signaling
  + 37 more...
.transcription regulatory region DNA binding
.protein kinase activator activity
.frizzled binding
.GTPase activator activity
.cytoplasm
.extracellular space
.proteinaceous extracellular matrix
.extracellular region
14 EBI-724076,EBI-353997 GNAI2  
  .regulation of calcium ion transport
.cell division
.negative regulation of synaptic transmission
  + 17 more...
.metal ion binding
.G-protein beta/gamma-subunit complex binding
.GTP binding
  + 3 more...
.extracellular exosome
.membrane raft
.vesicle
  + 8 more...
15 EBI-724076,EBI-745290 HOXB9  
  .cell chemotaxis
.canonical Wnt signaling pathway
.embryonic skeletal system development
  + 4 more...
.sequence-specific DNA binding .mitochondrion
.nucleoplasm
16 EBI-724076,EBI-746692 TNNI1  
  .ventricular cardiac muscle tissue morphogenesis
.muscle filament sliding
.regulation of striated muscle contraction
.metal ion binding .troponin complex
.cytosol
17 EBI-724076,EBI-2806671 GATA2  
  .regulation of forebrain neuron differentiation
.negative regulation of neural precursor cell proliferation
.GABAergic neuron differentiation
  + 29 more...
.C2H2 zinc finger domain binding
.zinc ion binding
.transcription factor binding
  + 5 more...
.protein complex
.nucleoplasm
18 EBI-724076,EBI-739899 ZBTB25  
  .gene expression
.transcription from RNA polymerase II promoter
.regulation of transcription from RNA polymerase II promoter
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.RNA polymerase II regulatory region sequence-specific DNA binding
.cytoplasm
.nucleoplasm
19 EBI-724076,EBI-1056863 HTR1B  
  .cellular response to temperature stimulus
.cellular response to alkaloid
.negative regulation of synaptic transmission, glutamatergic
  + 17 more...
.serotonin binding
.drug binding
.serotonin receptor activity
.integral component of plasma membrane
.plasma membrane
.cytoplasm
20 EBI-724076,EBI-745213 AQP1  
  .cation transmembrane transport
.maintenance of symbiont-containing vacuole by host
.ammonium transmembrane transport
  + 60 more...
.carbon dioxide transmembrane transporter activity
.nitric oxide transmembrane transporter activity
.transmembrane transporter activity
  + 8 more...
.extracellular exosome
.apical part of cell
.axon terminus
  + 12 more...
21 EBI-724076,EBI-301246 VHL  
  .cellular response to hypoxia
.negative regulation of transcription from RNA polymerase II promoter in response to hypoxia
.regulation of transcription from RNA polymerase II promoter in response to hypoxia
  + 10 more...
.ubiquitin protein ligase activity
.enzyme binding
.transcription factor binding
.ubiquitin-protein transferase activity
.intermediate filament cytoskeleton
.VCB complex
.membrane
  + 5 more...
22 EBI-724076,EBI-749129 ZNF136  
  .transcription from RNA polymerase II promoter
.negative regulation of transcription from RNA polymerase II promoter
.metal ion binding
.transcription corepressor activity
.DNA binding
.nucleus
23 EBI-724076,EBI-10213071 ZNF138  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
24 EBI-724076,EBI-745354 NR1H2  
  .regulation of cholesterol homeostasis
.positive regulation of secretion of lysosomal enzymes
.positive regulation of pancreatic juice secretion
  + 22 more...
.ATPase binding
.apolipoprotein A-I receptor binding
.zinc ion binding
  + 6 more...
.cytoplasm
.nucleoplasm
.nucleus
25 EBI-724076,EBI-746103 AQP5  
  .transmembrane transport
.camera-type eye morphogenesis
.saliva secretion
  + 8 more...
.glycerol channel activity
.water channel activity
.extracellular exosome
.apical plasma membrane
.basal plasma membrane
  + 4 more...
26 EBI-724076,EBI-10220734 GNG5  
  .cellular response to glucagon stimulus
.small molecule metabolic process
.synaptic transmission
  + 3 more...
.PDZ domain binding
.signal transducer activity
.GTPase activity
.extracellular exosome
.membrane
.plasma membrane
.heterotrimeric G-protein complex
27 EBI-724076,EBI-10221726 ADAMTSL3  
  .N/A .zinc ion binding
.metallopeptidase activity
.proteinaceous extracellular matrix
28 EBI-724076,EBI-10222656 AKAP17A  
  .regulation of RNA splicing
.B cell activation
.RNA splicing
  + 3 more...
.protein kinase A binding
.poly(A) RNA binding
.nucleotide binding
.nuclear speck
.cytoplasm
.spliceosomal complex
  + 2 more...
29 EBI-724076,EBI-10192698 CREB5  
  .adipose tissue development
.positive regulation of transcription, DNA-templated
.fat cell differentiation
.transcription from RNA polymerase II promoter
.metal ion binding
.sequence-specific DNA binding
.sequence-specific DNA binding transcription factor activity
.RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.extracellular exosome
.nucleus
30 EBI-724076,EBI-10223932 REG3A  
  .positive regulation of wound healing
.negative regulation of keratinocyte differentiation
.positive regulation of keratinocyte proliferation
  + 4 more...
.carbohydrate binding .cytoplasm
.extracellular space
31 EBI-724076,EBI-3951628 TYRO3  
  .platelet aggregation
.neuron cellular homeostasis
.vagina development
  + 20 more...
.phosphatidylinositol 3-kinase binding
.ATP binding
.receptor signaling protein tyrosine kinase activity
  + 2 more...
.integral component of plasma membrane
.endoplasmic reticulum membrane
.nuclear envelope
.nucleus
32 EBI-724076,EBI-10225757 ZNF844  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
33 EBI-724076,EBI-2602739 FAM27E3  
  .N/A .N/A .N/A
34 EBI-724076,EBI-10226430 RIPPLY1  
  .bone morphogenesis
.negative regulation of transcription, DNA-templated
.somite rostral/caudal axis specification
  + 4 more...
.N/A .nucleus
35 EBI-724076,EBI-10226932 FAAP100  
  .DNA repair .DNA binding .intermediate filament cytoskeleton
.Fanconi anaemia nuclear complex
.cytoplasm
.nucleoplasm
36 EBI-724076,EBI-10227379 ZNF155  
  .transcription, DNA-templated .metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
37 EBI-724076,EBI-781356 NR1H3  
  .positive regulation of cholesterol homeostasis
.regulation of cholesterol homeostasis
.negative regulation of secretion of lysosomal enzymes
  + 30 more...
.transcription regulatory region DNA binding
.sequence-specific DNA binding
.sterol response element binding
  + 6 more...
.RNA polymerase II transcription factor complex
.receptor complex
.nucleoplasm
  + 2 more...
38 EBI-724076,EBI-714158 PIN1  
  .negative regulation of cell motility
.negative regulation of ERK1 and ERK2 cascade
.regulation of pathway-restricted SMAD protein phosphorylation
  + 11 more...
.phosphothreonine binding
.phosphoserine binding
.GTPase activating protein binding
  + 2 more...
.midbody
.nuclear speck
.cytoplasm
  + 2 more...
39 EBI-724076,EBI-10232522 EIF4A2  
  .negative regulation of RNA-directed RNA polymerase activity
.cellular protein metabolic process
.cytokine-mediated signaling pathway
  + 8 more...
.poly(A) RNA binding
.ATPase activity
.ATP binding
  + 3 more...
.perinuclear region of cytoplasm
.eukaryotic translation initiation factor 4F complex
.cytosol
.nucleolus
40 EBI-724076,EBI-742350 TCEB3  
  .positive regulation of viral transcription
.protein ubiquitination involved in ubiquitin-dependent protein catabolic process
.viral process
  + 4 more...
.DNA binding .elongin complex
.integral component of membrane
.cytoplasm
  + 3 more...
41 EBI-724076,EBI-953879 PDIA5  
  .oxidation-reduction process
.cell redox homeostasis
.cellular protein metabolic process
  + 4 more...
.oxidoreductase activity
.protein disulfide isomerase activity
.endoplasmic reticulum membrane
.endoplasmic reticulum lumen
.endoplasmic reticulum
42 EBI-724076,EBI-7115319 ZNF266  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
43 EBI-724076,EBI-745934 CBX2  
  .development of primary sexual characteristics
.cellular protein metabolic process
.post-translational protein modification
  + 5 more...
.chromatin binding
.DNA binding
.PRC1 complex
.PcG protein complex
.nucleoplasm
  + 3 more...
44 EBI-724076,EBI-742828 LASP1  
  .positive regulation of signal transduction
.ion transport
.ion transmembrane transporter activity
.zinc ion binding
.SH3/SH2 adaptor activity
.extracellular exosome
.cortical actin cytoskeleton
.focal adhesion
45 EBI-724076,EBI-10217913 RTP5  
  .N/A .N/A .integral component of membrane
46 EBI-724076,EBI-2805673 KIAA0040  
  .N/A .N/A .N/A
47 EBI-724076,EBI-743675 SIX1  
  .regulation of skeletal muscle cell differentiation
.positive regulation of mesenchymal cell proliferation involved in ureter development
.negative regulation of branching involved in ureteric bud morphogenesis
  + 47 more...
.transcription regulatory region DNA binding
.sequence-specific DNA binding
.sequence-specific DNA binding transcription factor activity
  + 4 more...
.cytoplasm
.nucleolus
.transcription factor complex
  + 2 more...
48 EBI-724076,EBI-714215 TGIF1  
  .retina development in camera-type eye
.negative regulation of retinoic acid receptor signaling pathway
.positive regulation of fibroblast proliferation
  + 14 more...
.transcription corepressor activity
.sequence-specific DNA binding transcription factor activity
.chromatin binding
  + 2 more...
.nucleoplasm
49 EBI-724076,EBI-399189 VPS72  
  .somatic stem cell maintenance
.chromatin modification
.transcription, DNA-templated
  + 2 more...
.DNA binding .protein complex
.nucleoplasm
.nucleus
50 EBI-724076,EBI-10237274 ZNF79  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
51 EBI-724076,EBI-2555767 ZNF124  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
52 EBI-724076,EBI-7451846 AANAT  
  .cellular response to cAMP
.response to calcium ion
.response to corticosterone
  + 12 more...
.arylamine N-acetyltransferase activity
.aralkylamine N-acetyltransferase activity
.perinuclear region of cytoplasm
.cytosol
53 EBI-724076,EBI-10239029 C4orf26  
  .N/A .N/A .extracellular region
54 EBI-724076,EBI-719941 FAM161A  
  .response to stimulus
.cilium assembly
.visual perception
.N/A .ciliary basal body
.photoreceptor connecting cilium
.centrosome
.cytoplasm
55 EBI-724076,EBI-6425864 FOXD4L6  
  .cell differentiation
.anatomical structure morphogenesis
.transcription from RNA polymerase II promoter
.regulation of transcription from RNA polymerase II promoter
.sequence-specific DNA binding
.sequence-specific DNA binding RNA polymerase II transcription factor activity
.nucleus
56 EBI-724076,EBI-742029 RABL6  
  .small GTPase mediated signal transduction .GTP binding .centrosome
.cytoplasm
.nucleolus
.nucleus
57 EBI-724076,EBI-949255 PLEKHG4  
  .N/A .Rho guanyl-nucleotide exchange factor activity .N/A
58 EBI-724076,EBI-10243533 -  
  .N/A .N/A .N/A
59 EBI-724076,EBI-10245204 CC2D1B  
  .transcription from RNA polymerase II promoter
.negative regulation of transcription from RNA polymerase II promoter
.RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
.sequence-specific DNA binding RNA polymerase II transcription factor activity
.RNA polymerase II core promoter proximal region sequence-specific DNA binding
.intracellular membrane-bounded organelle
.nucleoplasm
60 EBI-724076,EBI-10245456 LCE3E  
  .keratinization .N/A .N/A
61 EBI-724076,EBI-744052 C10orf62  
  .N/A .N/A .N/A
62 EBI-724076,EBI-8640233 AVPI1  
  .cell cycle
.activation of MAPK activity
.N/A .N/A
63 EBI-724076,EBI-10245913 LCE1B  
  .keratinization .N/A .N/A
64 EBI-724076,EBI-10246358 LCE4A  
  .keratinization .N/A .N/A
65 EBI-724076,EBI-740686 DCAF8  
  .protein ubiquitination .N/A .Cul4-RING E3 ubiquitin ligase complex
.cytoplasm
.nucleus
66 EBI-724076,EBI-10248148 -  
  .N/A .N/A .N/A
67 EBI-724076,EBI-6447954 TTC23  
  .N/A .N/A .N/A
68 EBI-724076,EBI-10248413 -  
  .N/A .N/A .N/A
69 EBI-724076,EBI-7317823 C22orf39  
  .N/A .N/A .N/A
70 EBI-724076,EBI-8635958 SPATA8  
  .N/A .N/A .N/A
71 EBI-724076,EBI-7844656 TTLL10  
  .cellular protein modification process .N/A .N/A
72 EBI-724076,EBI-10225049 OLIG3  
  .spinal cord motor neuron migration
.spinal cord motor neuron cell fate specification
.DNA binding
.RNA polymerase II transcription corepressor activity
.nucleus
73 EBI-724076,EBI-10256685 PID1  
  .negative regulation of glucose import in response to insulin stimulus
.positive regulation of ATP biosynthetic process
.negative regulation of ATP biosynthetic process
  + 19 more...
.N/A .cytoplasm
.nucleoplasm
74 EBI-724076,EBI-10257651 LIMS2  
  .positive regulation of integrin-mediated signaling pathway
.negative regulation of hepatocyte proliferation
.negative regulation of neural precursor cell proliferation
  + 4 more...
.zinc ion binding .focal adhesion
.plasma membrane
.cytosol
.nucleus
75 EBI-724076,EBI-3919850 CDKL3  
  .dendrite extension
.positive regulation of dendrite morphogenesis
.negative regulation of axon extension
.cellular protein modification process
.ATP binding
.cyclin-dependent protein serine/threonine kinase activity
.protein kinase activity
.cytoplasm
.nucleus
76 EBI-724076,EBI-726439 ZNF440  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
77 EBI-724076,EBI-744311 CCDC116  
  .N/A .N/A .centrosome
78 EBI-724076,EBI-1104570 CEP57L1  
  .microtubule anchoring .N/A .microtubule
.microtubule organizing center
.cytoplasm
79 EBI-724076,EBI-5278328 ZNF101  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
80 EBI-724076,EBI-10267553 ZNF433  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
81 EBI-724076,EBI-747580 ZNF439  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
82 EBI-724076,EBI-741032 CNNM3  
  .ion transport .N/A .integral component of membrane
.membrane
.plasma membrane
83 EBI-724076,EBI-742060 TYMSOS  
  .N/A .N/A .N/A
84 EBI-724076,EBI-740727 ZNF417  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
85 EBI-724076,EBI-742750 BAHD1  
  .negative regulation of transcription, DNA-templated
.heterochromatin assembly
.transcription, DNA-templated
.chromatin silencing
.chromatin binding
.transcription regulatory region sequence-specific DNA binding
.chromatin silencing complex
.nucleoplasm
.chromatin
86 EBI-724076,EBI-10273713 ZNF564  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
87 EBI-724076,EBI-10275670 DCANP1  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.DNA binding .cytoplasm
.nucleus
88 EBI-724076,EBI-7199479 PTPMT1  
  .inositol phosphate dephosphorylation
.glycerophospholipid biosynthetic process
.small molecule metabolic process
  + 4 more...
.phosphatidylglycerophosphatase activity
.protein tyrosine/serine/threonine phosphatase activity
.protein tyrosine phosphatase activity
.phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
.integral component of mitochondrial inner membrane
.mitochondrion
.nucleus
89 EBI-724076,EBI-738731 PHLDA1  
  .FasL biosynthetic process
.positive regulation of apoptotic process
.forebrain neuron differentiation
.apoptotic process
.N/A .cytoplasmic vesicle membrane
.plasma membrane
.nucleolus
.nucleoplasm
90 EBI-724076,EBI-535849 HNRNPLL  
  .positive regulation of RNA splicing
.mRNA processing
.poly(A) RNA binding
.mRNA binding
.nucleotide binding
.ribonucleoprotein complex
.membrane
.nucleus
91 EBI-724076,EBI-10232538 PIH1D2  
  .N/A .Ral GTPase binding .N/A
92 EBI-724076,EBI-746964 NEU4  
  .small molecule metabolic process
.cellular protein metabolic process
.post-translational protein modification
  + 7 more...
.exo-alpha-(2->8)-sialidase activity
.exo-alpha-(2->6)-sialidase activity
.exo-alpha-(2->3)-sialidase activity
.exo-alpha-sialidase activity
.lysosomal lumen
.organelle inner membrane
.lysosome
.mitochondrion
93 EBI-724076,EBI-448771 DOCK2  
  .positive regulation of phagocytosis
.regulation of defense response to virus by virus
.alpha-beta T cell proliferation
  + 12 more...
.T cell receptor binding
.Rac guanyl-nucleotide exchange factor activity
.extracellular exosome
.membrane
.endomembrane system
  + 2 more...
94 EBI-724076,EBI-718419 PVRL2  
  .susceptibility to T cell mediated cytotoxicity
.establishment of mitochondrion localization
.regulation of immune response
  + 22 more...
.cell adhesion molecule binding
.protein homodimerization activity
.identical protein binding
  + 2 more...
.extracellular exosome
.integral component of membrane
.cell surface
  + 4 more...
95 EBI-724076,EBI-399080 KAT5  
  .positive regulation of protein acetylation
.cellular response to estradiol stimulus
.positive regulation of transcription from RNA polymerase II promoter
  + 14 more...
.repressing transcription factor binding
.androgen receptor binding
.metal ion binding
  + 2 more...
.perinuclear region of cytoplasm
.NuA4 histone acetyltransferase complex
.Piccolo NuA4 histone acetyltransferase complex
  + 6 more...
96 EBI-724076,EBI-395708 ZBTB9  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
97 EBI-724076,EBI-745810 C19orf60  
  .N/A .N/A .N/A
98 EBI-724076,EBI-5278764 CDCA7L  
  .positive regulation of cell proliferation
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.N/A .cytoplasm
.nucleolus
.nucleus
99 EBI-724076,EBI-751596 C8orf48  
  .N/A .N/A .N/A
100 EBI-724076,EBI-747175 ZNF607  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
101 EBI-724076,EBI-6427977 ZNF587  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
102 EBI-724076,EBI-746605 ZNF559  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
103 EBI-724076,EBI-744935 C20orf195  
  .N/A .N/A .extracellular exosome
104 EBI-724076,EBI-748297 BBS2  
  .protein localization to ciliary membrane
.regulation of cilium beat frequency involved in ciliary motility
.cilium morphogenesis
  + 23 more...
.RNA polymerase II repressing transcription factor binding .ciliary membrane
.ciliary basal body
.BBSome
  + 3 more...
105 EBI-724076,EBI-744099 ENKD1  
  .N/A .N/A .microtubule cytoskeleton
.cytoplasmic microtubule
106 EBI-724076,EBI-741626 FAM124B  
  .N/A .N/A .N/A
107 EBI-724076,EBI-347633 ZNF408  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.identical protein binding
.DNA binding
.nucleus
108 EBI-724076,EBI-5525855 MAGEF1  
  .N/A .N/A .extracellular exosome
109 EBI-724076,EBI-520427 PIDD1  
  .positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
.positive regulation of NF-kappaB transcription factor activity
.negative regulation of apoptotic process
  + 5 more...
.death receptor binding .Golgi apparatus
.cytoplasm
.nucleus
110 EBI-724076,EBI-7162175 BEX1  
  .positive regulation of sequence-specific DNA binding transcription factor activity
.positive regulation of transcription from RNA polymerase II promoter
.cell differentiation
.nervous system development
.RNA polymerase II activating transcription factor binding .cytoplasm
.transcription factor complex
.nucleus
111 EBI-724076,EBI-751092 HEYL  
  .negative regulation of androgen receptor activity
.proximal tubule development
.cellular response to BMP stimulus
  + 16 more...
.AF-1 domain binding
.protein heterodimerization activity
.microsatellite binding
  + 8 more...
.cytoplasm
.nucleoplasm
.nucleus
112 EBI-724076,EBI-9679045 DMRT3  
  .male sex differentiation
.regulation of odontogenesis of dentin-containing tooth
.ventral spinal cord interneuron specification
  + 4 more...
.protein heterodimerization activity
.metal ion binding
.protein homodimerization activity
  + 2 more...
.nucleus
113 EBI-724076,EBI-748927 NPDC1  
  .N/A .N/A .integral component of membrane
114 EBI-724076,EBI-10313866 C19orf66  
  .N/A .N/A .N/A
115 EBI-724076,EBI-719816 FBXO34  
  .N/A .N/A .cytoplasm
.nucleoplasm
116 EBI-724076,EBI-5666657 GPATCH2L  
  .N/A .N/A .N/A
117 EBI-724076,EBI-745520 ZNF581  
  .transcription from RNA polymerase II promoter
.regulation of transcription from RNA polymerase II promoter
.metal ion binding
.RNA polymerase II regulatory region sequence-specific DNA binding
.nucleus
118 EBI-724076,EBI-751020 THEG  
  .chaperone-mediated protein complex assembly
.cell differentiation
.spermatogenesis
.multicellular organismal development
.N/A .nucleus
119 EBI-724076,EBI-750394 SLC25A10  
  .sulfide oxidation, using sulfide:quinone oxidoreductase
.transmembrane transport
.small molecule metabolic process
  + 9 more...
.dicarboxylic acid transmembrane transporter activity .integral component of membrane
.mitochondrial inner membrane
.nucleus
120 EBI-724076,EBI-1105361 ZNF230  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
121 EBI-724076,EBI-10322867 ZNF223  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
122 EBI-724076,EBI-1105370 ZNF490  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
123 EBI-724076,EBI-717201 SPG7  
  .anterograde axon cargo transport
.nervous system development
.mitochondrion organization
.proteolysis
.unfolded protein binding
.zinc ion binding
.peptidase activity
  + 2 more...
.mitochondrial membrane
.integral component of membrane
.mitochondrion
124 EBI-724076,EBI-2511991 USP20  
  .protein K48-linked deubiquitination
.protein K63-linked deubiquitination
.regulation of proteasomal protein catabolic process
  + 4 more...
.zinc ion binding
.ubiquitin-specific protease activity
.cysteine-type endopeptidase activity
.G-protein coupled receptor binding
.perinuclear region of cytoplasm
.centrosome
125 EBI-724076,EBI-1045409 GTF3C5  
  .tRNA transcription from RNA polymerase III promoter
.5S class rRNA transcription from RNA polymerase III type 1 promoter
.skeletal muscle cell differentiation
  + 3 more...
.DNA binding .nucleoplasm
.transcription factor TFIIIC complex
126 EBI-724076,EBI-716006 MAGED1  
  .positive regulation of apoptotic signaling pathway
.extrinsic apoptotic signaling pathway in absence of ligand
.extrinsic apoptotic signaling pathway
  + 15 more...
.transcription coactivator activity .protein complex
.plasma membrane
.cytoplasm
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder33
blood16
bone27
brain12
embryonic tissue89
eye23
intestine8
kidney4
liver9
lung26
mammary gland6
muscle9
ovary29
pancreas4
placenta38
prostate5
skin18
testis9
uterus8
Health State
TissuesTPM*
normal17
bladder carcinoma56
chondrosarcoma12
germ cell tumor41
glioma93
kidney tumor14
leukemia21
liver tumor20
lung tumor9
pancreatic tumor9
primitive neuroectodermal tumor of the CNS39
skin tumor31
soft tissue/muscle tissue tumor7
uterine tumor22
Developmental Stage
TissuesTPM*
adult10
embryoid body100
blastocyst113
fetus21
infant42
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue26.7
adrenal gland1.7
appendix5.2
cerebral cortex7.7
duodenum1.9
esophagus13.1
gallbladder11.3
heart muscle1.4
kidney1.9
lung8
lymph node1.6
ovary5.7
placenta11
prostate6.2
salivary gland2.3
skin3.5
stomach3.8
testis3.8
thyroid gland1.4
urinary bladder8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*604971, gene) Myod family inhibitor; MDFIOMIM


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