Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q9BQ70)
Protein (NX_Q9BQ70)
Protein
Gene SymbolTCF25 to neXtProt (NX_Q9BQ70)
DescriptionTranscription factor 25
Chromosome16
Location16q24.3 (89940000 ~ 89977792) to Ensembl
Sequene Features : Isoforms 1, Variants 79, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.heart development
.transcription, DNA-templated
.negative regulation of transcription from RNA polymerase II promoter
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 79 7
2014-09-19protein level
1 62 7
2014-05-27protein level
1 62 7
2014-02-25protein level
1 62 5
2013-12-09protein level
1 42 5
2013-11-01protein level
1 39 4
2013-09-12protein level
1 39 4
2013-08-17protein level
1 39 4
2013-07-15protein level
1 29 3
2013-06-11protein level
1 29 3
2013-02-12protein level
1 16 1
2012-12-20protein level
1 15 1
2012-10-30protein level
1 20 1
2012-10-07protein level
1 20 1
2012-08-24protein level
1 19 1
2012-07-28protein level
1 19 1
2012-06-08protein level
1 19 1
2012-05-07protein level
1 15 1
2012-04-10protein level
1 15 1
2012-01-13protein level
1 11 1
2011-12-20protein level
1 11 1
2011-11-11protein level
1 11 1
2011-08-23protein level
1 11 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9BQ70-1
28 0 0 76618.4588
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-745182,EBI-711613 SAT1  
  .small molecule metabolic process
.regulation of cell proliferation
.cellular nitrogen compound metabolic process
  + 5 more...
.spermidine binding
.diamine N-acetyltransferase activity
.cytosol
.intracellular
2 EBI-745182,EBI-10178634 MAGEA11  
  .N/A .N/A .cytoplasm
.nucleoplasm
.nucleus
3 EBI-745182,EBI-749265 CCDC155  
  .chromosome localization to nuclear envelope involved in homologous chromosome segregation
.oogenesis
.spermatogenesis
  + 2 more...
.N/A .integral component of membrane
.nuclear outer membrane
.lateral element
.chromosome, telomeric region
4 EBI-745182,EBI-743771 APPBP2  
  .intracellular transport
.metabolic process
.intracellular protein transport
.microtubule motor activity .cytoplasmic vesicle membrane
.microtubule associated complex
.microtubule
  + 2 more...
5 EBI-745182,EBI-473189 GPRASP2  
  .N/A .beta-amyloid binding .cytoplasm
6 EBI-745182,EBI-398977 DERL1  
  .establishment of protein localization
.protein destabilization
.retrograde protein transport, ER to cytosol
  + 4 more...
.MHC class I protein binding
.receptor activity
.protease binding
.integral component of endoplasmic reticulum membrane
.integral component of membrane
.membrane
  + 4 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue310
ascites150
bladder33
blood122
bone97
bone marrow143
brain99
cervix82
connective tissue73
ear186
embryonic tissue126
esophagus198
eye105
heart89
intestine112
kidney61
larynx170
liver97
lung161
lymph203
lymph node122
mammary gland138
mouth75
muscle84
nerve128
ovary108
pancreas93
parathyroid97
pituitary gland60
placenta211
prostate84
salivary gland98
skin90
spleen56
stomach62
testis170
thymus62
thyroid171
tonsil176
uterus103
vascular38
Health State
TissuesTPM*
normal105
bladder carcinoma56
breast (mammary gland) tumor193
cervical tumor57
chondrosarcoma96
colorectal tumor62
esophageal tumor231
gastrointestinal tumor75
germ cell tumor60
glioma177
head and neck tumor97
kidney tumor87
leukemia190
liver tumor41
lung tumor204
lymphoma221
non-neoplasia41
ovarian tumor91
pancreatic tumor142
primitive neuroectodermal tumor of the CNS157
prostate cancer115
retinoblastoma86
skin tumor71
soft tissue/muscle tissue tumor127
uterine tumor88
Developmental Stage
TissuesTPM*
adult156
embryoid body128
blastocyst146
fetus105
infant85
juvenile125
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue62.8
adrenal gland68.3
appendix72
bone marrow83.1
cerebral cortex68.8
colon59.7
duodenum70.2
esophagus59.7
gallbladder75.3
heart muscle53.5
kidney51.5
liver40.8
lung70.5
lymph node86.8
ovary74
pancreas43.5
placenta72.6
prostate63.9
salivary gland62.2
skin77.6
small intestine65.3
spleen91.5
stomach81.2
testis86
thyroid gland93.7
urinary bladder82.5
Tissues
TissuesExpression level
adrenal glandHigh
appendixHigh
bone marrowHigh
breastMedium
bronchusHigh
cerebellumMedium
cerebral cortexHigh
cervix, uterineMedium
colonHigh
duodenumHigh
endometrium 1High
endometrium 2High
epididymisHigh
esophagusMedium
fallopian tubeHigh
gallbladderHigh
heart muscleMedium
hippocampusHigh
kidneyHigh
lateral ventricleHigh
liverHigh
lungMedium
lymph nodeMedium
nasopharynxHigh
oral mucosaMedium
ovaryHigh
pancreasMedium
parathyroid glandMedium
placentaHigh
prostateHigh
rectumHigh
salivary glandMedium
seminal vesicleHigh
skeletal muscleLow
skin 1Medium
skin 2Medium
small intestineHigh
smooth muscleMedium
soft tissue 1Low
soft tissue 2Low
spleenLow
stomach 1High
stomach 2High
testisHigh
thyroid glandMedium
tonsilHigh
urinary bladderMedium
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*612326, gene) Transcription factor 25; TCF25OMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center