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> Protein (NX_Q9BQ83)
Protein (NX_Q9BQ83)
Protein
Gene SymbolSLX1B to neXtProt (NX_Q9BQ83)
DescriptionStructure-specific endonuclease subunit SLX1
Chromosome16
Location16p11.2 (29465822 ~ 29469540) to Ensembl
Sequene Features : Isoforms 2, Variants 1, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.DNA double-strand break processing involved in repair via single-strand annealing
.DNA repair
.double-strand break repair via homologous recombination
.metal ion binding
.5'-flap endonuclease activity
.crossover junction endodeoxyribonuclease activity
.Slx1-Slx4 complex
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 1 0
2014-09-19protein level
2 1 0
2014-05-27protein level
2 1 0
2014-02-25protein level
2 1 0
2013-12-09protein level
2 1 0
2013-11-01protein level
2 1 0
2013-09-12protein level
2 1 0
2013-08-17protein level
2 1 0
2013-07-15protein level
2 1 0
2013-06-11protein level
2 1 0
2013-02-12protein level
2 1 0
2012-12-20protein level
2 1 0
2012-10-30protein level
2 3 0
2012-10-07protein level
2 3 0
2012-08-24protein level
2 3 0
2012-07-28protein level
2 4 0
2012-06-08protein level
2 6 0
2012-05-07protein level
2 6 0
2012-04-10protein level
2 5 0
2012-01-13protein level
2 4 0
2011-12-20protein level
2 4 0
2011-11-11protein level
2 4 0
2011-08-23protein level
2 4 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9BQ83-1
4 8 0 30751.297
NX_Q9BQ83-2
1 8 0 17999.7948
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2370858,EBI-2370740 SLX4  
  .response to intra-S DNA damage checkpoint signaling
.positive regulation of catalytic activity
.DNA double-strand break processing involved in repair via single-strand annealing
  + 4 more...
.5'-flap endonuclease activity
.enzyme activator activity
.Slx1-Slx4 complex
.cell junction
.cytoplasm
.nucleoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites50
blood49
bone139
brain28
cervix82
connective tissue13
embryonic tissue65
esophagus49
eye52
intestine68
kidney28
liver43
lung71
lymph112
lymph node77
mammary gland39
mouth30
muscle9
ovary108
pancreas18
placenta45
prostate21
salivary gland98
skin132
stomach73
testis11
thymus62
tonsil411
trachea19
uterus51
Health State
TissuesTPM*
normal40
breast (mammary gland) tumor32
cervical tumor57
chondrosarcoma144
colorectal tumor35
esophageal tumor57
gastrointestinal tumor75
germ cell tumor41
glioma65
head and neck tumor22
kidney tumor29
leukemia10
liver tumor31
lung tumor116
lymphoma180
non-neoplasia10
ovarian tumor39
pancreatic tumor19
primitive neuroectodermal tumor of the CNS47
prostate cancer19
retinoblastoma21
skin tumor215
soft tissue/muscle tissue tumor15
uterine tumor77
Developmental Stage
TissuesTPM*
adult42
embryoid body100
blastocyst65
fetus39
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue9.3
adrenal gland4.7
appendix12.6
bone marrow11.6
cerebral cortex4.5
colon15.1
duodenum33.9
esophagus2.5
gallbladder5.4
heart muscle2.5
kidney8
liver9.4
lung9.3
lymph node10.3
ovary2.3
pancreas2.8
placenta8.1
prostate4.7
salivary gland7.2
skin8.2
small intestine27.3
spleen12.9
stomach18.6
testis2.7
thyroid gland2.9
urinary bladder3.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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