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> Protein (NX_Q9BQ89)
Protein (NX_Q9BQ89)
Protein
Gene SymbolFAM110A to neXtProt (NX_Q9BQ89)
DescriptionProtein FAM110A
Chromosome20
Location20p13 (814358 ~ 838106) to Ensembl
Sequene Features : Isoforms 1, Variants 32, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .microtubule organizing center
.cytoplasm
.spindle pole
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 32 3
2014-09-19protein level
1 28 3
2014-05-27protein level
1 28 3
2014-02-25protein level
1 28 3
2013-12-09protein level
1 19 3
2013-11-01protein level
1 17 3
2013-09-12protein level
1 17 3
2013-08-17protein level
1 17 3
2013-07-15protein level
1 11 3
2013-06-11protein level
1 11 3
2013-02-12protein level
1 7 0
2012-12-20protein level
1 6 0
2012-10-30protein level
1 10 0
2012-10-07protein level
1 10 0
2012-08-24protein level
1 10 0
2012-07-28protein level
1 10 0
2012-06-08protein level
1 10 0
2012-05-07protein level
1 10 0
2012-04-10protein level
1 10 0
2012-01-13protein level
1 5 0
2011-12-20protein level
1 5 0
2011-11-11protein level
1 5 0
2011-08-23protein level
1 5 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9BQ89-1
13 0 0 31251.3035
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1752811,EBI-714135 STX11  
  .membrane fusion
.vesicle docking
.natural killer cell degranulation
  + 4 more...
.SNAP receptor activity
.SNARE binding
.SNARE complex
.integral component of membrane
.endomembrane system
  + 3 more...
2 EBI-1752811,EBI-748961 CCNDBP1  
  .regulation of cell cycle
.cell cycle
.N/A .cytoplasm
.nucleoplasm
.nucleus
3 EBI-1752811,EBI-719493 TRIM27  
  .negative regulation of viral release from host cell
.negative regulation of interleukin-2 secretion
.negative regulation of calcium ion import
  + 17 more...
.metal ion binding
.ligase activity
.zinc ion binding
  + 4 more...
.nuclear membrane
.PML body
.membrane
  + 6 more...
4 EBI-1752811,EBI-389883 NCK1  
  .negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
.negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
.negative regulation of PERK-mediated unfolded protein response
  + 23 more...
.eukaryotic initiation factor eIF2 binding
.receptor tyrosine kinase binding
.protein binding, bridging
  + 5 more...
.vesicle membrane
.cell-cell junction
.plasma membrane
  + 6 more...
5 EBI-1752811,EBI-739566 KRT15  
  .activation of mitophagy in response to mitochondrial depolarization
.epidermis development
.scaffold protein binding
.structural constituent of cytoskeleton
.extracellular exosome
.intermediate filament
.nucleus
6 EBI-1752811,EBI-740098 TRIM23  
  .positive regulation of catalytic activity
.protein ubiquitination
.viral process
.small GTPase mediated signal transduction
.identical protein binding
.GDP binding
.ligase activity
  + 5 more...
.extracellular exosome
.lysosomal membrane
.nucleus
.Golgi membrane
7 EBI-1752811,EBI-1181367 CDR2  
  .N/A .N/A .cytoplasm
8 EBI-1752811,EBI-618309 GOLGA2  
  .negative regulation of protein binding
.mitotic cell cycle
.syntaxin binding
.protein kinase binding
.Golgi cisterna membrane
.ER to Golgi transport vesicle
.cis-Golgi network
  + 4 more...
9 EBI-1752811,EBI-2340269 MKRN3  
  .protein ubiquitination .ligase activity
.zinc ion binding
.ribonucleoprotein complex
10 EBI-1752811,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
11 EBI-1752811,EBI-726876 RINT1  
  .regulation of signal transduction involved in mitotic G2 DNA damage checkpoint
.regulation of ER to Golgi vesicle-mediated transport
.Golgi vesicle transport
  + 2 more...
.N/A .endoplasmic reticulum membrane
.endoplasmic reticulum
12 EBI-1752811,EBI-749955 TRIM69  
  .apoptotic process .ligase activity
.zinc ion binding
.ubiquitin-protein transferase activity
.nuclear speck
.plasma membrane
.cytoplasm
.nucleus
13 EBI-1752811,EBI-739895 USHBP1  
  .N/A .PDZ domain binding .N/A
14 EBI-1752811,EBI-302345 PNMA1  
  .positive regulation of apoptotic process
.inflammatory response to antigenic stimulus
.N/A .focal adhesion
.cytoplasm
.nucleolus
15 EBI-1752811,EBI-2130429 TRIM54  
  .cell differentiation
.multicellular organismal development
.signal transduction
  + 2 more...
.zinc ion binding
.signal transducer activity
.Z disc
.microtubule associated complex
.microtubule
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
blood114
bone27
bone marrow20
brain9
cervix61
connective tissue6
embryonic tissue37
eye28
intestine12
kidney4
larynx42
liver19
lung17
lymph node22
mammary gland39
muscle94
nerve64
ovary9
parathyroid48
placenta14
prostate21
skin80
stomach10
testis13
uterus21
vascular19
Health State
TissuesTPM*
normal22
bladder carcinoma56
breast (mammary gland) tumor32
chondrosarcoma36
colorectal tumor17
gastrointestinal tumor33
glioma46
head and neck tumor7
leukemia31
lung tumor29
ovarian tumor13
primitive neuroectodermal tumor of the CNS157
prostate cancer28
skin tumor7
soft tissue/muscle tissue tumor87
uterine tumor33
Developmental Stage
TissuesTPM*
adult22
embryoid body42
blastocyst48
fetus25
juvenile71
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue2
adrenal gland2.5
appendix4.8
bone marrow5.2
cerebral cortex1.4
colon3.3
duodenum6.5
esophagus4
gallbladder2.2
kidney2.7
lung6.4
lymph node5.5
ovary1.2
placenta6.5
prostate6.9
salivary gland6.7
skin20
small intestine5.7
spleen14.8
stomach5
testis1.5
thyroid gland1.4
urinary bladder4.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*611393, gene) Family with sequence similarity 110, member a; FAM110AOMIM


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