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> Protein (NX_Q9BQD3)
Protein (NX_Q9BQD3)
Protein
Gene SymbolKXD1 to neXtProt (NX_Q9BQD3)
DescriptionKxDL motif-containing protein 1
Chromosome19
Location19p13.11 (18668572 ~ 18680197) to Ensembl
Sequene Features : Isoforms 1, Variants 8, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.vesicle-mediated transport .N/A .BLOC-1 complex
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 8 1
2014-09-19protein level
1 15 1
2014-05-27protein level
1 15 1
2014-02-25protein level
1 15 1
2013-12-09protein level
1 13 1
2013-11-01protein level
1 11 1
2013-09-12protein level
1 11 0
2013-08-17protein level
1 11 0
2013-07-15protein level
1 10 0
2013-06-11protein level
1 10 0
2013-02-12protein level
1 7 0
2012-12-20protein level
1 7 0
2012-10-30protein level
1 6 0
2012-10-07protein level
1 6 0
2012-08-24protein level
1 5 0
2012-07-28protein level
1 5 0
2012-06-08protein level
1 5 0
2012-05-07protein level
1 5 0
2012-04-10protein level
1 5 0
2012-01-13protein level
1 6 0
2011-12-20protein level
1 6 0
2011-11-11protein level
1 6 0
2011-08-23protein level
1 6 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9BQD3-1
5 0 0 19655.489
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-739657,EBI-355607 TPM3  
  .muscle filament sliding
.muscle contraction
.movement of cell or subcellular component
.N/A .extracellular exosome
.muscle thin filament tropomyosin
.cytoskeleton
  + 2 more...
2 EBI-739657,EBI-351158 TPM1  
  .cardiac muscle contraction
.ventricular cardiac muscle tissue morphogenesis
.positive regulation of stress fiber assembly
  + 15 more...
.structural constituent of muscle
.cytoskeletal protein binding
.structural constituent of cytoskeleton
.actin binding
.ruffle membrane
.bleb
.filamentous actin
  + 5 more...
3 EBI-739657,EBI-519141 MYH7  
  .cardiac muscle contraction
.ventricular cardiac muscle tissue morphogenesis
.regulation of slow-twitch skeletal muscle fiber contraction
  + 9 more...
.actin-dependent ATPase activity
.ATPase activity
.ATP binding
.microfilament motor activity
.myosin filament
.Z disc
.sarcomere
  + 6 more...
4 EBI-739657,EBI-358122 RPL9  
  .cellular protein metabolic process
.viral transcription
.viral life cycle
  + 8 more...
.rRNA binding
.structural constituent of ribosome
.RNA binding
.cytosolic large ribosomal subunit
.membrane
.focal adhesion
  + 5 more...
5 EBI-739657,EBI-739648 KRT81  
  .N/A .structural molecule activity .keratin filament
.extracellular space
6 EBI-739657,EBI-6657981 C4orf46  
  .N/A .N/A .cytoplasm
7 EBI-739657,EBI-744203 IFT20  
  .regulation of autophagic vacuole assembly
.regulation of cilium assembly
.protein localization to cilium
  + 13 more...
.N/A .ciliary base
.ciliary tip
.primary cilium
  + 13 more...
8 EBI-739657,EBI-740727 ZNF417  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
9 EBI-739657,EBI-749432 DYRK2  
  .negative regulation of NFAT protein import into nucleus
.positive regulation of glycogen biosynthetic process
.intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
  + 4 more...
.ubiquitin binding
.manganese ion binding
.ATP binding
  + 4 more...
.ribonucleoprotein complex
.cytoplasm
.nucleoplasm
  + 2 more...
10 EBI-739657,EBI-2805176 LRRC45  
  .N/A .N/A .centrosome
.cytoplasm
11 EBI-739657,EBI-2514791 HAUS1  
  .cell division
.centrosome organization
.spindle assembly
.mitotic nuclear division
.N/A .HAUS complex
.microtubule
.centrosome
  + 2 more...
12 EBI-739657,EBI-741885 CEP19  
  .N/A .N/A .ciliary basal body
.centriole
.spindle pole
13 EBI-739657,EBI-10295284 ARHGDIG  
  .regulation of small GTPase mediated signal transduction
.regulation of protein localization
.Rho protein signal transduction
  + 2 more...
.GTPase activator activity
.Rho GDP-dissociation inhibitor activity
.cytoplasmic membrane-bounded vesicle
.membrane
.cytosol
14 EBI-739657,EBI-373144 MAP1LC3B  
  .regulation of mitochondrion degradation
.membrane fusion
.nucleophagy
  + 3 more...
.microtubule binding .cytoplasmic vesicle
.organelle membrane
.extrinsic component of membrane
  + 9 more...
15 EBI-739657,EBI-720768 MAP1LC3A  
  .membrane fusion
.nucleophagy
.cellular response to nitrogen starvation
  + 2 more...
.phosphatidylethanolamine binding
.microtubule binding
.phospholipid binding
.cytoplasmic vesicle
.organelle membrane
.extrinsic component of membrane
  + 6 more...
16 EBI-739657,EBI-913954 RABGEF1  
  .negative regulation of Kit signaling pathway
.negative regulation of interleukin-6 secretion
.regulation of Fc receptor mediated stimulatory signaling pathway
  + 9 more...
.Rab GTPase binding
.Rab guanyl-nucleotide exchange factor activity
.zinc ion binding
  + 2 more...
.recycling endosome
.vesicle
.early endosome
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
ascites200
bladder66
blood40
bone139
bone marrow61
brain38
cervix82
connective tissue33
embryonic tissue84
eye33
heart122
intestine68
kidney80
larynx85
liver29
lung152
lymph45
lymph node178
mammary gland52
mouth45
muscle84
ovary206
pancreas60
parathyroid339
placenta42
prostate68
salivary gland197
skin132
spleen74
stomach52
testis45
thymus12
thyroid21
tonsil58
uterus73
vascular19
Health State
TissuesTPM*
normal51
bladder carcinoma113
breast (mammary gland) tumor53
chondrosarcoma96
colorectal tumor44
gastrointestinal tumor151
germ cell tumor68
glioma93
head and neck tumor59
kidney tumor29
leukemia148
liver tumor20
lung tumor184
lymphoma27
ovarian tumor157
pancreatic tumor47
primitive neuroectodermal tumor of the CNS70
prostate cancer86
retinoblastoma43
skin tumor175
soft tissue/muscle tissue tumor127
uterine tumor44
Developmental Stage
TissuesTPM*
adult59
embryoid body114
blastocyst113
fetus70
infant85
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue44.9
adrenal gland35.2
appendix47.3
bone marrow34.5
cerebral cortex33.4
colon38.8
duodenum34.5
esophagus37.5
gallbladder41.7
heart muscle36.2
kidney28
liver22.2
lung45.9
lymph node55.9
ovary48.4
pancreas22.5
placenta47.3
prostate36.5
salivary gland37.2
skin37
small intestine33.8
spleen48.4
stomach40.9
testis49.7
thyroid gland41.4
urinary bladder47.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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