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> Protein (NX_Q9BRI3)
Protein (NX_Q9BRI3)
Protein
Gene SymbolSLC30A2 to neXtProt (NX_Q9BRI3)
DescriptionZinc transporter 2
Chromosome1
Location1p36.11 (26363743 ~ 26372624) to Ensembl
Sequene Features : Isoforms 2, Variants 41, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of sequestering of zinc ion
.transmembrane transport
.zinc II ion transport
.cation transmembrane transporter activity .integral component of membrane
.late endosome
.lysosomal membrane
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 41 0
2014-09-19protein level
2 34 0
2014-05-27protein level
2 34 0
2014-02-25protein level
2 34 0
2013-12-09protein level
2 25 0
2013-11-01protein level
2 24 0
2013-09-12protein level
2 24 0
2013-08-17protein level
2 24 0
2013-07-15protein level
2 18 0
2013-06-11protein level
2 18 0
2013-02-12protein level
2 7 0
2012-12-20protein level
2 7 0
2012-10-30protein level
2 9 0
2012-10-07protein level
2 9 0
2012-08-24protein level
2 9 0
2012-07-28protein level
2 9 0
2012-06-08protein level
2 9 0
2012-05-07protein level
2 9 0
2012-04-10protein level
2 9 0
2012-01-13protein level
2 7 0
2011-12-20protein level
2 7 0
2011-11-11protein level
2 7 0
2011-08-23protein level
2 7 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9BRI3-1
1 11 0 35154.9898
NX_Q9BRI3-2
3 11 0 40537.6352
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-8644112,EBI-2873970 CCL4  
  .positive regulation of natural killer cell chemotaxis
.cell chemotaxis
.positive regulation of calcium ion transport
  + 11 more...
.identical protein binding
.CCR5 chemokine receptor binding
.CCR1 chemokine receptor binding
  + 2 more...
.extracellular space
.extracellular region
2 EBI-8644112,EBI-3919694 PVR  
  .susceptibility to T cell mediated cytotoxicity
.regulation of immune response
.positive regulation of natural killer cell mediated cytotoxicity
  + 7 more...
.cell adhesion molecule binding
.receptor activity
.extracellular exosome
.integral component of membrane
.cell surface
  + 4 more...
3 EBI-8644112,EBI-749265 CCDC155  
  .chromosome localization to nuclear envelope involved in homologous chromosome segregation
.oogenesis
.spermatogenesis
  + 2 more...
.N/A .integral component of membrane
.nuclear outer membrane
.lateral element
.chromosome, telomeric region
4 EBI-8644112,EBI-10271156 CCL4L1  
  .cell chemotaxis
.immune response
.inflammatory response
.N/A .extracellular space
5 EBI-8644112,EBI-10303054 ADAM33  
  .proteolysis .zinc ion binding
.metalloendopeptidase activity
.integral component of membrane
6 EBI-8644112,EBI-2851995 TNFRSF12A  
  .positive regulation of extrinsic apoptotic signaling pathway
.extrinsic apoptotic signaling pathway
.regulation of wound healing
  + 5 more...
.N/A .integral component of membrane
.cell surface
.plasma membrane
.ruffle
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
cervix20
embryonic tissue4
eye9
kidney61
lung2
ovary19
placenta105
thyroid21
uterus12
Health State
TissuesTPM*
normal14
cervical tumor28
head and neck tumor7
lung tumor9
ovarian tumor26
Developmental Stage
TissuesTPM*
adult18
embryoid body14
fetus1
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
gallbladder9.2
heart muscle3.9
kidney19.1
pancreas39
placenta12.8
salivary gland1.4
thyroid gland28.9
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(-608118, phenotype) Zinc in breast milk, reducedOMIM
2(*609617, gene) Solute carrier family 30 (zinc transporter), member 2; SLC30A2OMIM


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