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> Protein (NX_Q9BRR9)
Protein (NX_Q9BRR9)
Protein
Gene SymbolARHGAP9 to neXtProt (NX_Q9BRR9)
DescriptionRho GTPase-activating protein 9
Chromosome12
Location12q13.3 (57866038 ~ 57882597) to Ensembl
Sequene Features : Isoforms 5, Variants 117, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of small GTPase mediated signal transduction
.positive regulation of GTPase activity
.small GTPase mediated signal transduction
.phosphatidylinositol-3,4,5-trisphosphate binding
.GTPase activator activity
.cytosol
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
5 117 5
2014-09-19protein level
5 91 5
2014-05-27protein level
5 91 5
2014-02-25protein level
5 91 5
2013-12-09protein level
5 71 5
2013-11-01protein level
5 66 5
2013-09-12protein level
5 66 5
2013-08-17protein level
5 66 5
2013-07-15protein level
5 53 2
2013-06-11protein level
5 53 2
2013-02-12protein level
4 27 4
2012-12-20protein level
4 25 4
2012-10-30protein level
4 31 4
2012-10-07protein level
4 31 1
2012-08-24protein level
4 25 1
2012-07-28protein level
4 25 1
2012-06-08protein level
4 26 1
2012-05-07protein level
4 26 1
2012-04-10protein level
3 26 1
2012-01-13protein level
3 16 1
2011-12-20protein level
3 16 1
2011-11-11protein level
3 16 1
2011-08-23protein level
3 16 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9BRR9-1
0 33 1 83207.6429
NX_Q9BRR9-2
0 33 1 81099.5869
NX_Q9BRR9-3
0 26 1 63252.5593
NX_Q9BRR9-4
0 26 1 61144.5033
NX_Q9BRR9-5
0 30 1 70825.4266
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-750254,EBI-401755 GRB2  
  .positive regulation of reactive oxygen species metabolic process
.cellular response to ionizing radiation
.branching involved in labyrinthine layer morphogenesis
  + 25 more...
.ephrin receptor binding
.poly(A) RNA binding
.insulin receptor substrate binding
  + 6 more...
.Grb2-EGFR complex
.extracellular exosome
.vesicle membrane
  + 10 more...
2 EBI-750254,EBI-701903 FHL2  
  .heart trabecula formation
.ventricular cardiac muscle cell development
.atrial cardiac muscle cell development
  + 9 more...
.androgen receptor binding
.identical protein binding
.zinc ion binding
  + 2 more...
.M band
.Z disc
.actin cytoskeleton
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland30
blood654
bone13
bone marrow41
brain16
cervix61
connective tissue67
heart11
intestine47
kidney4
liver9
lung26
lymph45
lymph node55
mammary gland6
mouth30
muscle84
ovary9
pharynx24
placenta28
prostate10
spleen1516
stomach31
testis13
thymus815
tonsil235
trachea38
uterus34
vascular38
Health State
TissuesTPM*
normal71
breast (mammary gland) tumor10
chondrosarcoma24
gastrointestinal tumor8
germ cell tumor3
head and neck tumor14
leukemia317
lung tumor19
lymphoma55
non-neoplasia93
primitive neuroectodermal tumor of the CNS7
soft tissue/muscle tissue tumor55
uterine tumor11
Developmental Stage
TissuesTPM*
adult34
neonate225
fetus19
juvenile71
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue16.6
adrenal gland8.6
appendix98.3
bone marrow132.5
cerebral cortex5
colon13.5
duodenum18.7
esophagus10.5
gallbladder28.6
heart muscle4.7
kidney3.7
liver5.3
lung28.1
lymph node149.2
ovary3
pancreas2.5
placenta12.9
prostate6.7
salivary gland8.7
skin6.3
small intestine26.2
spleen112.4
stomach19.4
testis28.9
thyroid gland4.4
urinary bladder32.7
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(+610576, gene/phenotype) Rho gtpase-activating protein 9; ARHGAP9OMIM


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