Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_Q9BRU9)
Protein (NX_Q9BRU9)
Protein
Gene SymbolUTP23 to neXtProt (NX_Q9BRU9)
DescriptionrRNA-processing protein UTP23 homolog
Chromosome8
Location8q24.11 (117778742 ~ 117861702) to Ensembl
Sequene Features : Isoforms 2, Variants 32, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) .small ribosomal subunit rRNA binding
.poly(A) RNA binding
.small-subunit processome
.nucleolus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 32 2
2014-09-19protein level
2 26 2
2014-05-27protein level
2 26 2
2014-02-25protein level
2 26 2
2013-12-09protein level
2 21 2
2013-11-01protein level
2 21 1
2013-09-12protein level
2 21 1
2013-08-17protein level
2 21 1
2013-07-15protein level
2 12 1
2013-06-11protein level
2 12 1
2013-02-12protein level
2 7 1
2012-12-20protein level
2 7 1
2012-10-30protein level
2 10 1
2012-10-07protein level
2 10 1
2012-08-24protein level
2 10 1
2012-07-28protein level
2 9 1
2012-06-08protein level
2 10 1
2012-05-07protein level
2 9 1
2012-04-10protein level
2 9 1
2012-01-13protein level
2 7 1
2011-12-20protein level
2 7 1
2011-11-11transcript level
2 7 0
2011-08-23transcript level
2 7 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9BRU9-1
5 2 0 28384.1707
NX_Q9BRU9-2
2 2 0 16669.4144
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-5457544,EBI-742764 PDE9A  
  .cGMP-mediated signaling
.metabolic process
.blood coagulation
.signal transduction
.3',5'-cyclic-GMP phosphodiesterase activity
.metal ion binding
.3',5'-cyclic-nucleotide phosphodiesterase activity
.perinuclear region of cytoplasm
.perikaryon
.ruffle membrane
  + 3 more...
2 EBI-5457544,EBI-719493 TRIM27  
  .negative regulation of viral release from host cell
.negative regulation of interleukin-2 secretion
.negative regulation of calcium ion import
  + 17 more...
.metal ion binding
.ligase activity
.zinc ion binding
  + 4 more...
.nuclear membrane
.PML body
.membrane
  + 6 more...
3 EBI-5457544,EBI-533224 TCF4  
  .protein-DNA complex assembly
.positive regulation of transcription from RNA polymerase II promoter
.positive regulation of transcription, DNA-templated
  + 3 more...
.E-box binding
.protein heterodimerization activity
.bHLH transcription factor binding
  + 9 more...
.transcription factor complex
.nucleus
4 EBI-5457544,EBI-740098 TRIM23  
  .positive regulation of catalytic activity
.protein ubiquitination
.viral process
.small GTPase mediated signal transduction
.identical protein binding
.GDP binding
.ligase activity
  + 5 more...
.extracellular exosome
.lysosomal membrane
.nucleus
.Golgi membrane
5 EBI-5457544,EBI-10172150 KRTAP10-5  
  .N/A .identical protein binding .keratin filament
6 EBI-5457544,EBI-10171774 KRTAP10-8  
  .N/A .N/A .keratin filament
7 EBI-5457544,EBI-10172052 KRTAP10-9  
  .N/A .N/A .keratin filament
8 EBI-5457544,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
9 EBI-5457544,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
10 EBI-5457544,EBI-945833 NOTCH2NL  
  .cell differentiation
.multicellular organismal development
.Notch signaling pathway
.calcium ion binding .cytoplasm
.extracellular region
11 EBI-5457544,EBI-10172526 MID2  
  .negative regulation of viral release from host cell
.positive regulation of NF-kappaB transcription factor activity
.positive regulation of sequence-specific DNA binding transcription factor activity
  + 6 more...
.phosphoprotein binding
.protein heterodimerization activity
.protein homodimerization activity
  + 3 more...
.extracellular exosome
.microtubule
.cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder33
bone41
brain33
cervix20
connective tissue13
embryonic tissue28
eye23
heart33
intestine30
kidney14
liver9
lung5
lymph node22
mammary gland52
mouth15
muscle37
ovary9
pancreas9
pharynx24
placenta24
prostate47
salivary gland49
skin66
testis16
trachea77
uterus17
vascular19
Health State
TissuesTPM*
normal21
bladder carcinoma56
breast (mammary gland) tumor75
cervical tumor28
chondrosarcoma12
colorectal tumor26
gastrointestinal tumor25
germ cell tumor41
glioma18
head and neck tumor7
kidney tumor14
liver tumor10
ovarian tumor13
pancreatic tumor9
primitive neuroectodermal tumor of the CNS47
prostate cancer48
skin tumor111
soft tissue/muscle tissue tumor23
uterine tumor11
Developmental Stage
TissuesTPM*
adult20
embryoid body42
blastocyst32
fetus16
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue8.9
adrenal gland8.6
appendix13.7
bone marrow15.6
cerebral cortex11.1
colon7.6
duodenum6.9
esophagus8.2
gallbladder7
heart muscle6.3
kidney7.2
liver3.7
lung7.9
lymph node12.7
ovary14.3
pancreas4.3
placenta9.4
prostate8.1
salivary gland6.6
skin5.2
small intestine6.9
spleen10.5
stomach7.6
testis10.1
thyroid gland11.5
urinary bladder10.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center