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> Protein (NX_Q9BRV8)
Protein (NX_Q9BRV8)
Protein
Gene SymbolSIKE1 to neXtProt (NX_Q9BRV8)
DescriptionSuppressor of IKBKE 1
Chromosome1
Location1p13.2 (115312100 ~ 115323306) to Ensembl
Sequene Features : Isoforms 2, Variants 20, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.innate immune response .N/A .cytosol
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 20 1
2014-09-19protein level
2 14 1
2014-05-27protein level
2 14 1
2014-02-25protein level
2 14 1
2013-12-09protein level
2 12 1
2013-11-01protein level
2 10 1
2013-09-12protein level
2 10 1
2013-08-17protein level
2 10 1
2013-07-15protein level
2 9 0
2013-06-11protein level
2 9 0
2013-02-12protein level
2 5 2
2012-12-20protein level
2 5 2
2012-10-30protein level
2 4 2
2012-10-07protein level
2 4 1
2012-08-24protein level
2 3 1
2012-07-28protein level
2 3 1
2012-06-08protein level
2 6 1
2012-05-07protein level
2 6 1
2012-04-10protein level
2 6 1
2012-01-13protein level
2 6 1
2011-12-20protein level
2 6 1
2011-11-11protein level
2 6 1
2011-08-23protein level
2 6 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9BRV8-1
1 11 0 23705.8731
NX_Q9BRV8-2
2 11 0 24245.2004
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1773646,EBI-765817 TRAF3IP3  
  .N/A .N/A .integral component of membrane
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood8
bone27
bone marrow20
brain29
connective tissue13
embryonic tissue70
eye38
heart55
intestine25
kidney28
larynx85
liver19
lung23
lymph node167
mammary gland66
mouth15
muscle94
nerve128
ovary29
pancreas4
pharynx49
placenta31
prostate21
salivary gland49
skin33
spleen37
stomach10
testis41
thymus50
trachea77
uterus25
vascular96
Health State
TissuesTPM*
normal39
breast (mammary gland) tumor96
chondrosarcoma12
colorectal tumor8
gastrointestinal tumor8
germ cell tumor64
glioma18
head and neck tumor22
kidney tumor29
leukemia31
liver tumor31
lung tumor19
lymphoma13
non-neoplasia10
ovarian tumor39
prostate cancer19
skin tumor31
soft tissue/muscle tissue tumor23
uterine tumor22
Developmental Stage
TissuesTPM*
adult32
embryoid body57
blastocyst113
neonate32
fetus48
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue12.5
adrenal gland11.4
appendix16.6
bone marrow14.4
cerebral cortex10
colon14.8
duodenum17.7
esophagus13.2
gallbladder10.5
heart muscle9.6
kidney14.4
liver11.4
lung10.8
lymph node16.4
ovary12
pancreas5.3
placenta11.6
prostate12.7
salivary gland7.7
skin15.4
small intestine10.9
spleen16.1
stomach14.3
testis11.3
thyroid gland15.5
urinary bladder12.2
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowMedium
breastMedium
bronchusMedium
cerebellumMedium
cerebral cortexMedium
cervix, uterineMedium
colonMedium
duodenumMedium
endometrium 1Medium
endometrium 2Medium
epididymisMedium
esophagusLow
fallopian tubeMedium
gallbladderMedium
heart muscleLow
hippocampusMedium
kidneyMedium
lateral ventricleMedium
liverMedium
lungMedium
lymph nodeMedium
nasopharynxMedium
oral mucosaLow
ovaryMedium
pancreasMedium
parathyroid glandMedium
placentaMedium
prostateMedium
rectumMedium
salivary glandLow
seminal vesicleMedium
skeletal muscleMedium
skin 1Low
skin 2Low
small intestineMedium
smooth muscleLow
soft tissue 1Low
soft tissue 2Medium
stomach 1Medium
stomach 2Medium
testisMedium
thyroid glandMedium
tonsilMedium
urinary bladderMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*611656, gene) Suppressor of ikk-epsilonOMIM


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