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> Protein (NX_Q9BRX9)
Protein (NX_Q9BRX9)
Protein
Gene SymbolWDR83 to neXtProt (NX_Q9BRX9)
DescriptionWD repeat domain-containing protein 83
Chromosome19
Location19p13.2 (12777614 ~ 12786646) to Ensembl
Sequene Features : Isoforms 1, Variants 28, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.mRNA splicing, via spliceosome
.RNA splicing, via transesterification reactions
.N/A .catalytic step 2 spliceosome
.cytoplasm
.spliceosomal complex
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 28 3
2014-09-19protein level
1 22 3
2014-05-27protein level
1 22 3
2014-02-25protein level
1 22 3
2013-12-09protein level
1 14 3
2013-11-01protein level
1 14 3
2013-09-12protein level
1 14 3
2013-08-17protein level
1 14 3
2013-07-15protein level
1 9 0
2013-06-11protein level
1 9 0
2013-02-12protein level
1 7 0
2012-12-20protein level
1 7 0
2012-10-30protein level
1 8 0
2012-10-07protein level
1 8 0
2012-08-24protein level
1 8 0
2012-07-28protein level
1 8 0
2012-06-08protein level
1 10 0
2012-05-07protein level
1 7 0
2012-04-10protein level
1 7 0
2012-01-13protein level
1 6 0
2011-12-20protein level
1 6 0
2011-11-11protein level
1 6 0
2011-08-23protein level
1 6 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9BRX9-1
15 0 0 34320.7421
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-7705033,EBI-766589 SNRPC  
  .mRNA splicing, via spliceosome
.mRNA 5'-splice site recognition
.spliceosomal snRNP assembly
.poly(A) RNA binding
.protein homodimerization activity
.zinc ion binding
  + 2 more...
.U2-type prespliceosome
.Cajal body
.U1 snRNP
  + 2 more...
2 EBI-7705033,EBI-751001 KEAP1  
  .cellular response to interleukin-4
.regulation of epidermal cell differentiation
.negative regulation of sequence-specific DNA binding transcription factor activity
  + 6 more...
.transcription factor binding .Cul3-RING ubiquitin ligase complex
.midbody
.cytosol
  + 4 more...
3 EBI-7705033,EBI-348469 SF3B4  
  .positive regulation of mRNA splicing, via spliceosome
.gene expression
.RNA splicing
  + 3 more...
.poly(A) RNA binding
.nucleotide binding
.U12-type spliceosomal complex
.spliceosomal complex
.nucleoplasm
4 EBI-7705033,EBI-538479 PRPF8  
  .gene expression
.RNA splicing
.mRNA processing
  + 3 more...
.pre-mRNA intronic binding
.K63-linked polyubiquitin binding
.poly(A) RNA binding
  + 5 more...
.catalytic step 2 spliceosome
.nuclear speck
.membrane
  + 3 more...
5 EBI-7705033,EBI-607755 UBL5  
  .positive regulation of protein targeting to mitochondrion
.cellular protein modification process
.mRNA splicing, via spliceosome
.protein tag .cytoplasm
.nucleus
6 EBI-7705033,EBI-2557649 PPIL1  
  .protein folding
.protein peptidyl-prolyl isomerization
.mRNA splicing, via spliceosome
.peptidyl-prolyl cis-trans isomerase activity .catalytic step 2 spliceosome
.extracellular exosome
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
ascites50
bladder33
blood24
bone69
brain15
cervix20
connective tissue6
embryonic tissue37
eye43
intestine12
kidney9
liver9
lung23
lymph22
mammary gland26
mouth30
muscle37
nerve64
pancreas4
placenta17
prostate26
skin14
spleen18
stomach10
testis18
umbilical cord72
uterus21
Health State
TissuesTPM*
normal18
breast (mammary gland) tumor42
cervical tumor28
chondrosarcoma60
gastrointestinal tumor33
germ cell tumor18
glioma18
head and neck tumor14
kidney tumor14
leukemia10
liver tumor20
lung tumor29
lymphoma13
primitive neuroectodermal tumor of the CNS39
prostate cancer19
skin tumor15
soft tissue/muscle tissue tumor39
uterine tumor33
Developmental Stage
TissuesTPM*
adult16
embryoid body42
neonate32
fetus12
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue5.1
adrenal gland6.3
appendix6.8
bone marrow8.8
cerebral cortex8.4
colon4.7
duodenum6.1
esophagus4.5
gallbladder5.3
heart muscle5.7
kidney8.4
liver2.5
lung7.3
lymph node10.5
ovary8.1
pancreas4.2
placenta5.6
prostate7
salivary gland7.9
skin11.7
small intestine6.2
spleen9
stomach8.4
testis11.3
thyroid gland8.7
urinary bladder6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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