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> Protein (NX_Q9BSJ8)
Protein (NX_Q9BSJ8)
Protein
Gene SymbolESYT1 to neXtProt (NX_Q9BSJ8)
DescriptionExtended synaptotagmin-1
Chromosome12
Location12q13.2 (56512034 ~ 56538455) to Ensembl
Sequene Features : Isoforms 2, Variants 128, PTMs 18 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.lipid transport .metal ion binding
.phospholipid binding
.organelle membrane contact site
.integral component of endoplasmic reticulum membrane
.membrane
.plasma membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 128 18
2014-09-19protein level
2 98 18
2014-05-27protein level
2 98 17
2014-02-25protein level
2 97 17
2013-12-09protein level
2 75 17
2013-11-01protein level
2 73 14
2013-09-12protein level
2 73 14
2013-08-17protein level
2 73 14
2013-07-15protein level
2 47 9
2013-06-11protein level
2 47 9
2013-02-12protein level
2 33 14
2012-12-20protein level
2 29 14
2012-10-30protein level
2 32 14
2012-10-07protein level
2 32 7
2012-08-24protein level
2 30 7
2012-07-28protein level
2 30 7
2012-06-08protein level
2 35 7
2012-05-07protein level
2 30 7
2012-04-10protein level
2 30 7
2012-01-13protein level
2 13 7
2011-12-20protein level
2 13 7
2011-11-11protein level
2 13 6
2011-08-23protein level
2 13 6
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9BSJ8-1
0 46 0 122779.5949
NX_Q9BSJ8-2
1 46 0 123925.1346
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-355956,EBI-3184170 ESYT2  
  .endocytosis
.lipid transport
.identical protein binding
.phosphatidylinositol binding
.phosphatidylcholine binding
  + 3 more...
.organelle membrane contact site
.extrinsic component of cytoplasmic side of plasma membrane
.intrinsic component of endoplasmic reticulum membrane
  + 2 more...
2 EBI-355956,EBI-8771391 ESYT3  
  .lipid transport .metal ion binding
.phospholipid binding
.organelle membrane contact site
.extrinsic component of cytoplasmic side of plasma membrane
.intrinsic component of endoplasmic reticulum membrane
.integral component of plasma membrane
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue777
adrenal gland60
ascites50
bladder66
blood81
bone111
bone marrow266
brain131
connective tissue80
embryonic tissue150
esophagus49
eye90
heart212
intestine150
kidney170
larynx127
liver73
lung119
lymph383
lymph node111
mammary gland138
mouth408
muscle169
nerve257
ovary275
pancreas135
pharynx122
placenta81
prostate158
salivary gland49
skin104
spleen243
stomach73
testis165
thymus263
thyroid85
tonsil58
trachea405
umbilical cord1598
uterus254
vascular116
Health State
TissuesTPM*
normal123
adrenal tumor158
bladder carcinoma56
breast (mammary gland) tumor182
chondrosarcoma132
colorectal tumor168
esophageal tumor57
gastrointestinal tumor118
germ cell tumor212
glioma83
head and neck tumor194
kidney tumor333
leukemia201
liver tumor135
lung tumor87
lymphoma249
non-neoplasia93
ovarian tumor144
pancreatic tumor161
primitive neuroectodermal tumor of the CNS102
prostate cancer173
retinoblastoma86
skin tumor79
soft tissue/muscle tissue tumor79
uterine tumor122
Developmental Stage
TissuesTPM*
adult114
embryoid body228
blastocyst146
neonate418
fetus87
juvenile287
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue92.4
adrenal gland34.4
appendix39.8
bone marrow18.5
cerebral cortex13.3
colon31.6
duodenum16.3
esophagus30.6
gallbladder34.2
heart muscle21.6
kidney19.5
liver26
lung44.4
lymph node51
ovary35.7
pancreas18.7
placenta32.4
prostate29.5
salivary gland22.8
skin27.6
small intestine18
spleen42.6
stomach21.3
testis16.1
thyroid gland30.9
urinary bladder44.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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