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> Protein (NX_Q9BSW7)
Protein (NX_Q9BSW7)
Protein
Gene SymbolSYT17 to neXtProt (NX_Q9BSW7)
DescriptionSynaptotagmin-17
Chromosome16
Location16p12.3 (19179293 ~ 19279652) to Ensembl
Sequene Features : Isoforms 1, Variants 79, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of dendrite extension
.calcium ion-dependent exocytosis of neurotransmitter
.regulation of calcium ion-dependent exocytosis
  + 2 more...
.clathrin binding
.syntaxin binding
.calcium-dependent phospholipid binding
.calcium ion binding
.plasma membrane
.trans-Golgi network
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 79 1
2014-09-19protein level
1 50 1
2014-05-27protein level
1 50 1
2014-02-25protein level
1 50 1
2013-12-09protein level
1 44 1
2013-11-01protein level
1 38 1
2013-09-12protein level
1 38 1
2013-08-17protein level
1 38 1
2013-07-15protein level
1 27 1
2013-06-11protein level
1 27 1
2013-02-12protein level
1 13 0
2012-12-20protein level
1 13 0
2012-10-30protein level
1 15 0
2012-10-07protein level
1 15 0
2012-08-24protein level
1 14 0
2012-07-28protein level
1 14 0
2012-06-08protein level
1 15 0
2012-05-07protein level
1 12 0
2012-04-10protein level
1 12 0
2012-01-13protein level
1 3 0
2011-12-20protein level
1 3 0
2011-11-11protein level
1 3 0
2011-08-23protein level
1 3 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9BSW7-1
25 0 0 53815.1443
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-745392,EBI-2864512 MEOX1  
  .sclerotome development
.somite development
.hematopoietic stem cell differentiation
  + 2 more...
.sequence-specific DNA binding
.sequence-specific DNA binding transcription factor activity
.chromatin binding
  + 3 more...
.cytoplasm
.nucleus
2 EBI-745392,EBI-355744 TRAF2  
  .positive regulation of extrinsic apoptotic signaling pathway
.regulation of extrinsic apoptotic signaling pathway via death domain receptors
.negative regulation of neuron death
  + 35 more...
.sphingolipid binding
.identical protein binding
.thioesterase binding
  + 10 more...
.IRE1-TRAF2-ASK1 complex
.TRAF2-GSTP1 complex
.membrane raft
  + 7 more...
3 EBI-745392,EBI-745305 IKZF1  
  .retina development in camera-type eye
.positive regulation of NK T cell differentiation
.Peyer's patch development
  + 17 more...
.metal ion binding
.sequence-specific DNA binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.protein complex
.cytoplasm
.pericentric heterochromatin
.nucleus
4 EBI-745392,EBI-747225 RUNDC3A  
  .small GTPase mediated signal transduction .GTPase regulator activity
.guanylate cyclase activator activity
.plasma membrane
.cytosol
5 EBI-745392,EBI-10175124 FAM9B  
  .spermatid development .N/A .nucleoplasm
6 EBI-745392,EBI-739624 CEP70  
  .organelle organization
.mitotic cell cycle
.G2/M transition of mitotic cell cycle
.N/A .nuclear membrane
.cytosol
.centrosome
  + 2 more...
7 EBI-745392,EBI-741977 CEP63  
  .cell division
.spindle assembly
.signal transduction in response to DNA damage
  + 6 more...
.N/A .cytosol
.centriole
.centrosome
.spindle pole
8 EBI-745392,EBI-747981 CHMP4A  
  .negative regulation of autophagic vacuole assembly
.negative regulation of neuron death
.membrane tubulation
  + 14 more...
.ATPase binding
.protein homodimerization activity
.identical protein binding
.lipid binding
.extracellular exosome
.late endosome membrane
.cytoplasmic vesicle membrane
  + 7 more...
9 EBI-745392,EBI-740897 NIF3L1  
  .negative regulation of nucleic acid-templated transcription
.positive regulation of transcription, DNA-templated
.neuron differentiation
.identical protein binding
.transcription factor binding
.mitochondrion
.cytoplasm
.nucleus
10 EBI-745392,EBI-10172526 MID2  
  .negative regulation of viral release from host cell
.positive regulation of NF-kappaB transcription factor activity
.positive regulation of sequence-specific DNA binding transcription factor activity
  + 6 more...
.phosphoprotein binding
.protein heterodimerization activity
.protein homodimerization activity
  + 3 more...
.extracellular exosome
.microtubule
.cytoplasm
11 EBI-745392,EBI-2212028 SSX2IP  
  .regulation of cell motility
.centrosome organization
.cilium assembly
  + 3 more...
.N/A .protein complex
.ciliary basal body
.centriolar satellite
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood8
brain34
cervix20
connective tissue6
embryonic tissue4
eye28
intestine8
kidney18
lung20
lymph node44
mammary gland19
mouth15
muscle18
nerve64
ovary9
pancreas37
parathyroid48
pituitary gland242
placenta7
salivary gland49
stomach10
thyroid42
tonsil58
uterus8
Health State
TissuesTPM*
normal15
breast (mammary gland) tumor21
chondrosarcoma12
colorectal tumor17
gastrointestinal tumor8
glioma55
head and neck tumor22
kidney tumor29
leukemia10
lung tumor19
lymphoma27
non-neoplasia10
pancreatic tumor57
primitive neuroectodermal tumor of the CNS47
soft tissue/muscle tissue tumor7
uterine tumor22
Developmental Stage
TissuesTPM*
adult11
embryoid body14
fetus3
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue3.6
adrenal gland5.5
appendix1.3
cerebral cortex23.4
colon2.5
duodenum3.4
esophagus4
gallbladder1.4
kidney3.7
liver6.9
lung8.5
lymph node3.4
pancreas2.1
placenta4
prostate9
salivary gland1.4
skin7.8
small intestine2.1
spleen1.4
stomach3.8
thyroid gland8.1
urinary bladder5.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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