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> Protein (NX_Q9BT88)
Protein (NX_Q9BT88)
Protein
Gene SymbolSYT11 to neXtProt (NX_Q9BT88)
DescriptionSynaptotagmin-11
Chromosome1
Location1q22 (155829300 ~ 155854990) to Ensembl
Sequene Features : Isoforms 1, Variants 63, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.calcium ion-dependent exocytosis of neurotransmitter
.negative regulation of neurotransmitter secretion
.regulation of calcium ion-dependent exocytosis
  + 2 more...
.clathrin binding
.syntaxin binding
.calcium-dependent phospholipid binding
.calcium ion binding
.synaptic vesicle membrane
.cell junction
.synaptic vesicle
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 63 4
2014-09-19protein level
1 51 4
2014-05-27protein level
1 51 4
2014-02-25protein level
1 49 4
2013-12-09protein level
1 45 4
2013-11-01protein level
1 44 4
2013-09-12protein level
1 44 4
2013-08-17protein level
1 44 4
2013-07-15protein level
1 24 4
2013-06-11protein level
1 24 4
2013-02-12protein level
1 10 0
2012-12-20protein level
1 10 0
2012-10-30protein level
1 10 0
2012-10-07protein level
1 10 0
2012-08-24protein level
1 10 0
2012-07-28protein level
1 10 0
2012-06-08protein level
1 14 0
2012-05-07protein level
1 11 0
2012-04-10protein level
1 11 0
2012-01-13protein level
1 8 0
2011-12-20protein level
1 8 0
2011-11-11protein level
1 8 0
2011-08-23protein level
1 8 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9BT88-1
14 0 0 48266.2288
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-751770,EBI-347996 SGTA  
  .viral process .N/A .cytoplasm
2 EBI-751770,EBI-743771 APPBP2  
  .intracellular transport
.metabolic process
.intracellular protein transport
.microtubule motor activity .cytoplasmic vesicle membrane
.microtubule associated complex
.microtubule
  + 2 more...
3 EBI-751770,EBI-6308763 ATP13A2  
  .cellular response to manganese ion
.metabolic process
.cation transport
.metal ion binding
.ATPase activity
.ATP binding
.integral component of membrane
.lysosomal membrane
.lysosome
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
blood24
bone27
brain444
cervix41
connective tissue26
embryonic tissue23
esophagus49
eye105
heart55
intestine8
kidney52
liver19
lung26
lymph22
lymph node55
mammary gland13
mouth30
muscle84
nerve128
pancreas56
pharynx49
pituitary gland181
placenta3
prostate10
skin42
stomach41
testis89
thymus12
trachea38
uterus30
vascular58
Health State
TissuesTPM*
normal166
adrenal tumor79
cervical tumor28
chondrosarcoma84
colorectal tumor8
gastrointestinal tumor25
germ cell tumor144
glioma214
head and neck tumor22
kidney tumor130
liver tumor20
lymphoma55
non-neoplasia62
pancreatic tumor76
primitive neuroectodermal tumor of the CNS55
retinoblastoma43
skin tumor7
uterine tumor22
Developmental Stage
TissuesTPM*
adult62
embryoid body14
blastocyst16
neonate64
fetus102
infant85
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue7
adrenal gland19.5
appendix9
bone marrow2.4
cerebral cortex208.4
colon6.6
duodenum2.9
esophagus5.5
gallbladder12.4
heart muscle10.5
kidney4.7
lung7.9
lymph node11
ovary13.4
pancreas1.6
placenta6.2
prostate10.5
salivary gland1.7
skin1.3
small intestine4.7
spleen9.4
stomach4.1
testis7.2
thyroid gland2.4
urinary bladder11.8
Tissues
TissuesExpression level
adrenal glandLow
appendixMedium
bronchusLow
cerebellumMedium
cerebral cortexMedium
cervix, uterineLow
colonMedium
duodenumMedium
fallopian tubeLow
gallbladderLow
hippocampusMedium
kidneyMedium
lateral ventricleLow
parathyroid glandMedium
rectumMedium
seminal vesicleMedium
skin 1Low
small intestineMedium
soft tissue 1Medium
soft tissue 2Medium
thyroid glandLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*608741, gene) Synaptotagmin 11; SYT11OMIM


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