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> Protein (NX_Q9BUD6)
Protein (NX_Q9BUD6)
Protein
Gene SymbolSPON2 to neXtProt (NX_Q9BUD6)
DescriptionSpondin-2
Chromosome4
Location4p16.3 (1160720 ~ 1202750) to Ensembl
Sequene Features : Isoforms 1, Variants 38, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cellular response to lipopolysaccharide
.positive regulation of macrophage cytokine production
.defense response to virus
  + 9 more...
.metal ion binding
.antigen binding
.lipopolysaccharide binding
.extracellular exosome
.extracellular space
.proteinaceous extracellular matrix
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 38 2
2014-09-19protein level
1 26 2
2014-05-27protein level
1 26 2
2014-02-25protein level
1 26 2
2013-12-09protein level
1 20 2
2013-11-01protein level
1 19 2
2013-09-12protein level
1 19 2
2013-08-17protein level
1 19 2
2013-07-15protein level
1 13 2
2013-06-11protein level
1 13 2
2013-02-12protein level
1 9 2
2012-12-20protein level
1 9 2
2012-10-30protein level
1 9 2
2012-10-07protein level
1 9 2
2012-08-24protein level
1 7 2
2012-07-28protein level
1 7 2
2012-06-08protein level
1 9 2
2012-05-07protein level
1 9 2
2012-04-10protein level
1 9 2
2012-01-13protein level
1 6 2
2011-12-20protein level
1 7 2
2011-11-11protein level
1 7 2
2011-08-23protein level
1 7 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9BUD6-1
14 0 0 35823.652
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10298801,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland91
ascites25
blood8
bone13
brain4
intestine8
liver14
lung8
mammary gland6
nerve64
ovary9
pancreas4
placenta3
prostate5
spleen18
uterus21
Health State
TissuesTPM*
normal3
breast (mammary gland) tumor21
cervical tumor144
chondrosarcoma84
colorectal tumor17
gastrointestinal tumor8
leukemia10
lung tumor9
non-neoplasia10
Developmental Stage
TissuesTPM*
adult165
embryoid body14
neonate160
fetus26
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue25.9
adrenal gland17.6
appendix19.6
bone marrow16
cerebral cortex1.9
colon21.1
duodenum20.6
esophagus9.5
gallbladder32.2
heart muscle6.1
kidney8.8
liver19.5
lung15.3
lymph node7
ovary9.4
pancreas4.5
placenta18.5
prostate113.5
salivary gland6.5
skin22.4
small intestine28.7
spleen18.6
stomach25.9
testis5.1
thyroid gland1.8
urinary bladder30.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*605918, gene) Spondin 2; SPON2OMIM


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