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> Protein (NX_Q9BUI4)
Protein (NX_Q9BUI4)
Protein
Gene SymbolPOLR3C to neXtProt (NX_Q9BUI4)
DescriptionDNA-directed RNA polymerase III subunit RPC3
Chromosome1
Location1q21.1 (145592605 ~ 145611025) to Ensembl
Sequene Features : Isoforms 1, Variants 61, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.defense response to virus
.positive regulation of innate immune response
.innate immune response
  + 7 more...
.DNA-directed RNA polymerase activity
.DNA binding
.cytosol
.DNA-directed RNA polymerase III complex
.nucleoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 61 3
2014-09-19protein level
1 47 3
2014-05-27protein level
1 47 3
2014-02-25protein level
1 47 3
2013-12-09protein level
1 38 3
2013-11-01protein level
1 37 3
2013-09-12protein level
1 37 3
2013-08-17protein level
1 37 3
2013-07-15protein level
1 31 3
2013-06-11protein level
1 31 3
2013-02-12protein level
1 19 2
2012-12-20protein level
1 19 2
2012-10-30protein level
1 19 2
2012-10-07protein level
1 19 2
2012-08-24protein level
1 13 2
2012-07-28protein level
1 13 2
2012-06-08protein level
1 23 2
2012-05-07protein level
1 22 2
2012-04-10protein level
1 22 2
2012-01-13protein level
1 19 2
2011-12-20protein level
1 19 2
2011-11-11protein level
1 19 2
2011-08-23protein level
1 19 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9BUI4-1
26 0 0 60573.0626
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-5452779,EBI-719493 TRIM27  
  .negative regulation of viral release from host cell
.negative regulation of interleukin-2 secretion
.negative regulation of calcium ion import
  + 17 more...
.metal ion binding
.ligase activity
.zinc ion binding
  + 4 more...
.nuclear membrane
.PML body
.membrane
  + 6 more...
2 EBI-5452779,EBI-876651 ROCK1  
  .regulation of cell motility
.regulation of establishment of cell polarity
.positive regulation of focal adhesion assembly
  + 27 more...
.metal ion binding
.ATP binding
.protein serine/threonine kinase activity
.protein kinase activity
.bleb
.lamellipodium
.plasma membrane
  + 5 more...
3 EBI-5452779,EBI-10171633 PNMA5  
  .positive regulation of apoptotic process .identical protein binding .N/A
4 EBI-5452779,EBI-1378139 ROPN1  
  .small GTPase mediated signal transduction .N/A .cytoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites25
bladder33
blood139
bone13
bone marrow20
brain18
connective tissue26
embryonic tissue42
eye28
heart11
intestine51
kidney61
larynx42
liver4
lung38
lymph45
lymph node66
mammary gland119
mouth15
muscle28
ovary29
pancreas4
pharynx24
placenta38
prostate15
skin47
stomach104
testis29
thymus12
thyroid21
uterus21
vascular38
Health State
TissuesTPM*
normal29
adrenal tumor79
breast (mammary gland) tumor150
colorectal tumor88
gastrointestinal tumor101
germ cell tumor15
glioma46
head and neck tumor22
kidney tumor43
leukemia127
liver tumor10
lung tumor68
lymphoma27
non-neoplasia31
ovarian tumor26
pancreatic tumor9
primitive neuroectodermal tumor of the CNS102
prostate cancer9
retinoblastoma86
skin tumor47
soft tissue/muscle tissue tumor15
uterine tumor55
Developmental Stage
TissuesTPM*
adult48
embryoid body42
blastocyst65
fetus35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue13.8
adrenal gland10.4
appendix14.9
bone marrow14.3
cerebral cortex11.5
colon13.5
duodenum11.1
esophagus14.3
gallbladder16.2
heart muscle10
kidney12.5
liver7.6
lung12.2
lymph node19
ovary20.2
pancreas8
placenta13
prostate9.7
salivary gland9.9
skin14.5
small intestine12.4
spleen15.9
stomach12.6
testis33.6
thyroid gland16.9
urinary bladder16.7
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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