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> Protein (NX_Q9BUJ2)
Protein (NX_Q9BUJ2)
Protein
Gene SymbolHNRNPUL1 to neXtProt (NX_Q9BUJ2)
DescriptionHeterogeneous nuclear ribonucleoprotein U-like protein 1
Chromosome19
Location19q13.2 (41768401 ~ 41813503) to Ensembl
Sequene Features : Isoforms 5, Variants 95, PTMs 22 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.gene expression
.response to virus
.RNA splicing
  + 4 more...
.poly(A) RNA binding
.enzyme binding
.RNA binding
.ribonucleoprotein complex
.nucleoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
5 95 22
2014-09-19protein level
5 64 22
2014-05-27protein level
5 64 22
2014-02-25protein level
5 64 14
2013-12-09protein level
5 50 14
2013-11-01protein level
5 50 10
2013-09-12protein level
5 50 10
2013-08-17protein level
5 50 10
2013-07-15protein level
5 30 8
2013-06-11protein level
5 30 8
2013-02-12protein level
5 14 43
2012-12-20protein level
5 17 39
2012-10-30protein level
5 19 39
2012-10-07protein level
5 19 9
2012-08-24protein level
5 18 9
2012-07-28protein level
5 18 9
2012-06-08protein level
5 8 9
2012-05-07protein level
5 8 9
2012-04-10protein level
5 8 9
2012-01-13protein level
5 8 9
2011-12-20protein level
5 9 9
2011-11-11protein level
5 9 7
2011-08-23protein level
5 9 7
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9BUJ2-1
0 31 0 95679.0218
NX_Q9BUJ2-2
1 30 0 90235.5519
NX_Q9BUJ2-3
2 25 0 84446.9155
NX_Q9BUJ2-4
0 29 0 84740.7664
NX_Q9BUJ2-5
3 7 0 42162.8717
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1018153,EBI-2559305 VPS37C  
  .intracellular transport of virus
.membrane organization
.viral protein processing
  + 5 more...
.calcium-dependent protein binding .extracellular exosome
.late endosome membrane
.endosome membrane
.ESCRT I complex
2 EBI-1018153,EBI-743923 WWP2  
  .regulation of potassium ion transmembrane transporter activity
.protein K63-linked ubiquitination
.protein autoubiquitination
  + 13 more...
.ligase activity
.transcription factor binding
.ubiquitin-protein transferase activity
.RNA polymerase II transcription factor binding
.extracellular exosome
.membrane
.cytoplasm
  + 2 more...
3 EBI-1018153,EBI-741237 SORBS3  
  .positive regulation of stress fiber assembly
.positive regulation of cytoskeleton organization
.positive regulation of MAPK cascade
  + 5 more...
.vinculin binding
.structural constituent of cytoskeleton
.focal adhesion
.cytoskeleton
.cytosol
.nucleus
4 EBI-1018153,EBI-352986 HNRNPF  
  .regulation of RNA splicing
.gene expression
.RNA splicing
  + 2 more...
.poly(A) RNA binding
.single-stranded RNA binding
.RNA binding
.nucleotide binding
.catalytic step 2 spliceosome
.membrane
.nucleoplasm
.nucleus
5 EBI-1018153,EBI-10175039 TP53BP2  
  .positive regulation of execution phase of apoptosis
.intrinsic apoptotic signaling pathway by p53 class mediator
.negative regulation of cell cycle
  + 7 more...
.NF-kappaB binding
.identical protein binding
.SH3/SH2 adaptor activity
.p53 binding
.perinuclear region of cytoplasm
.cytoplasm
.nucleus
6 EBI-1018153,EBI-348469 SF3B4  
  .positive regulation of mRNA splicing, via spliceosome
.gene expression
.RNA splicing
  + 3 more...
.poly(A) RNA binding
.nucleotide binding
.U12-type spliceosomal complex
.spliceosomal complex
.nucleoplasm
7 EBI-1018153,EBI-395421 SMN2  
  .ncRNA metabolic process
.gene expression
.nervous system development
  + 2 more...
.identical protein binding
.RNA binding
.Gemini of coiled bodies
.SMN-Sm protein complex
.SMN complex
  + 7 more...
8 EBI-1018153,EBI-948630 DZIP3  
  .protein polyubiquitination .poly(A) RNA binding
.polyubiquitin binding
.phosphatase binding
  + 4 more...
.cytoplasm
9 EBI-1018153,EBI-741424 MAPK1IP1L  
  .N/A .N/A .N/A
10 EBI-1018153,EBI-715531 RBM4B  
  .entrainment of circadian clock by photoperiod
.circadian regulation of gene expression
.positive regulation of gene expression
  + 4 more...
.poly(A) RNA binding
.zinc ion binding
.nucleotide binding
.nucleolus
11 EBI-1018153,EBI-711221 BRD7  
  .negative regulation of G1/S transition of mitotic cell cycle
.positive regulation of transcription, DNA-templated
.negative regulation of transcription, DNA-templated
  + 6 more...
.lysine-acetylated histone binding
.transcription regulatory region DNA binding
.histone binding
  + 4 more...
.cytoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland91
ascites476
bladder133
blood155
bone41
bone marrow102
brain258
cervix350
connective tissue6
ear124
embryonic tissue4
eye4
heart111
intestine4
kidney118
larynx213
liver151
lung2
lymph993
lymph node11
mammary gland290
mouth483
muscle9
ovary423
pancreas4
parathyroid97
placenta113
prostate142
salivary gland394
skin441
spleen131
stomach104
testis278
thymus665
thyroid257
tonsil998
trachea193
umbilical cord72
uterus215
vascular232
Health State
TissuesTPM*
normal1
adrenal tumor237
bladder carcinoma113
breast (mammary gland) tumor311
cervical tumor492
chondrosarcoma48
colorectal tumor346
gastrointestinal tumor312
germ cell tumor368
glioma298
head and neck tumor358
kidney tumor246
leukemia169
liver tumor197
lung tumor437
lymphoma637
non-neoplasia155
ovarian tumor367
pancreatic tumor9
primitive neuroectodermal tumor of the CNS519
prostate cancer163
retinoblastoma473
skin tumor630
soft tissue/muscle tissue tumor7
uterine tumor133
Developmental Stage
TissuesTPM*
adult2
embryoid body328
blastocyst16
neonate225
fetus298
infant127
juvenile143
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue70.5
adrenal gland49.4
appendix74.6
bone marrow94.2
cerebral cortex44.7
colon69.8
duodenum64.5
esophagus65.5
gallbladder56.7
heart muscle55.8
kidney46
liver28
lung69
lymph node89.5
ovary105.9
pancreas32.4
placenta47.1
prostate54.3
salivary gland61.6
skin67.8
small intestine64.9
spleen83.1
stomach67.7
testis92.3
thyroid gland69.2
urinary bladder69.7
Tissues
TissuesExpression level
adrenal glandHigh
appendixHigh
bone marrowHigh
breastHigh
bronchusHigh
cerebellumHigh
cerebral cortexHigh
cervix, uterineHigh
colonHigh
duodenumHigh
endometrium 1High
endometrium 2High
epididymisHigh
esophagusHigh
fallopian tubeHigh
gallbladderHigh
heart muscleHigh
hippocampusHigh
kidneyHigh
lateral ventricleHigh
liverHigh
lungHigh
lymph nodeHigh
nasopharynxHigh
oral mucosaHigh
ovaryHigh
pancreasHigh
parathyroid glandHigh
placentaHigh
prostateHigh
rectumHigh
salivary glandHigh
seminal vesicleHigh
skeletal muscleMedium
skin 1High
skin 2High
small intestineHigh
smooth muscleMedium
soft tissue 1Medium
soft tissue 2Medium
spleenHigh
stomach 1High
stomach 2High
testisHigh
thyroid glandHigh
tonsilHigh
urinary bladderHigh
vaginaHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*605800, gene) Heterogeneous nuclear ribonucleoprotein u-like 1; HNRNPUL1OMIM


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