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> Protein (NX_Q9BUT1)
Protein (NX_Q9BUT1)
Protein
Gene SymbolBDH2 to neXtProt (NX_Q9BUT1)
Description3-hydroxybutyrate dehydrogenase type 2
Chromosome4
Location4q24 (104000592 ~ 104021040) to Ensembl
Sequene Features : Isoforms 3, Variants 38, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.iron ion homeostasis
.heme metabolic process
.epithelial cell differentiation
  + 2 more...
.NAD binding
.oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
.3-hydroxybutyrate dehydrogenase activity
.extracellular exosome
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 38 2
2014-09-19protein level
3 33 2
2014-05-27protein level
3 33 2
2014-02-25protein level
3 33 2
2013-12-09protein level
3 27 2
2013-11-01protein level
3 27 0
2013-09-12protein level
3 27 0
2013-08-17protein level
3 27 0
2013-07-15protein level
3 21 0
2013-06-11protein level
3 21 0
2013-02-12protein level
3 14 5
2012-12-20protein level
3 12 5
2012-10-30protein level
3 14 5
2012-10-07protein level
3 14 2
2012-08-24protein level
3 13 2
2012-07-28protein level
3 13 2
2012-06-08protein level
3 17 2
2012-05-07protein level
3 17 2
2012-04-10protein level
3 17 2
2012-01-13protein level
3 7 2
2011-12-20protein level
3 7 2
2011-11-11protein level
3 7 2
2011-08-23protein level
3 7 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9BUT1-1
0 10 0 26706.6461
NX_Q9BUT1-2
1 6 0 19196.8709
NX_Q9BUT1-3
0 5 0 15615.8921
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
adrenal gland212
ascites75
bladder234
blood16
bone125
brain117
cervix164
connective tissue80
ear62
embryonic tissue61
esophagus198
eye47
heart156
intestine77
kidney185
larynx42
liver43
lung110
lymph node33
mammary gland33
mouth45
muscle47
nerve64
ovary39
pancreas18
parathyroid971
pharynx24
placenta63
prostate63
salivary gland49
skin71
spleen131
stomach73
testis34
thymus112
thyroid42
trachea96
umbilical cord217
uterus301
vascular96
Health State
TissuesTPM*
normal96
adrenal tumor79
breast (mammary gland) tumor32
cervical tumor28
chondrosarcoma156
colorectal tumor8
esophageal tumor173
gastrointestinal tumor67
germ cell tumor26
glioma83
head and neck tumor22
kidney tumor145
leukemia10
liver tumor52
lung tumor29
non-neoplasia175
ovarian tumor26
pancreatic tumor19
primitive neuroectodermal tumor of the CNS70
prostate cancer48
retinoblastoma21
skin tumor71
soft tissue/muscle tissue tumor39
uterine tumor144
Developmental Stage
TissuesTPM*
adult69
embryoid body85
blastocyst32
neonate128
fetus95
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue16.4
adrenal gland40.2
appendix9.8
bone marrow3.9
cerebral cortex12.4
colon16.5
duodenum57.1
esophagus15.5
gallbladder34
heart muscle16.3
kidney109.1
liver24.3
lung23.3
lymph node11.4
ovary41.4
pancreas6
placenta11.1
prostate20.9
salivary gland11.1
skin16.4
small intestine47.5
spleen12.2
stomach18.5
testis12.8
thyroid gland24
urinary bladder20.8
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
breastLow
bronchusMedium
cerebellumLow
cerebral cortexMedium
cervix, uterineMedium
colonMedium
duodenumMedium
endometrium 1Low
endometrium 2Low
epididymisLow
esophagusLow
fallopian tubeMedium
gallbladderMedium
hippocampusMedium
kidneyHigh
lateral ventricleMedium
liverHigh
lungHigh
lymph nodeLow
nasopharynxMedium
pancreasMedium
parathyroid glandMedium
placentaMedium
prostateLow
rectumMedium
salivary glandMedium
seminal vesicleMedium
skin 1Low
skin 2Low
small intestineMedium
soft tissue 1Medium
soft tissue 2Medium
stomach 1Medium
stomach 2Medium
testisMedium
thyroid glandMedium
tonsilLow
urinary bladderLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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