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> Protein (NX_Q9BV90)
Protein (NX_Q9BV90)
Protein
Gene SymbolSNRNP25 to neXtProt (NX_Q9BV90)
DescriptionU11/U12 small nuclear ribonucleoprotein 25 kDa protein
Chromosome16
Location16p13.3 (103010 ~ 107669) to Ensembl
Sequene Features : Isoforms 1, Variants 14, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.RNA splicing
.mRNA processing
.N/A .intercellular bridge
.cytoplasm
.U12-type spliceosomal complex
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 14 0
2014-09-19protein level
1 13 0
2014-05-27protein level
1 13 0
2014-02-25protein level
1 13 0
2013-12-09protein level
1 10 0
2013-11-01protein level
1 10 0
2013-09-12protein level
1 10 0
2013-08-17protein level
1 10 0
2013-07-15protein level
1 6 0
2013-06-11protein level
1 6 0
2013-02-12protein level
1 3 0
2012-12-20protein level
1 3 0
2012-10-30protein level
1 3 0
2012-10-07protein level
1 3 0
2012-08-24protein level
1 3 0
2012-07-28protein level
1 3 0
2012-06-08protein level
1 4 0
2012-05-07protein level
1 4 0
2012-04-10protein level
1 4 0
2012-01-13protein level
1 3 0
2011-12-20protein level
1 3 0
2011-11-11protein level
1 3 0
2011-08-23protein level
1 3 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9BV90-1
4 0 0 15259.9338
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-9675976,EBI-307352 REL  
  .negative regulation of neuron death
.positive regulation of transcription from RNA polymerase II promoter
.innate immune response
  + 10 more...
.sequence-specific DNA binding transcription factor activity
.chromatin binding
.RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.RNA polymerase II distal enhancer sequence-specific DNA binding
.I-kappaB/NF-kappaB complex
.cytosol
.transcription factor complex
  + 2 more...
2 EBI-9675976,EBI-355744 TRAF2  
  .positive regulation of extrinsic apoptotic signaling pathway
.regulation of extrinsic apoptotic signaling pathway via death domain receptors
.negative regulation of neuron death
  + 35 more...
.sphingolipid binding
.identical protein binding
.thioesterase binding
  + 10 more...
.IRE1-TRAF2-ASK1 complex
.TRAF2-GSTP1 complex
.membrane raft
  + 7 more...
3 EBI-9675976,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
4 EBI-9675976,EBI-2349927 EFHC2  
  .N/A .calcium ion binding .N/A
5 EBI-9675976,EBI-3920396 C11orf57  
  .N/A .N/A .N/A
6 EBI-9675976,EBI-746909 CPSF7  
  .protein tetramerization
.mRNA 3'-end processing
.gene expression
  + 4 more...
.poly(A) RNA binding
.nucleotide binding
.membrane
.mRNA cleavage factor complex
.nucleoplasm
.nucleus
7 EBI-9675976,EBI-739832 LNX1  
  .protein homooligomerization
.protein ubiquitination involved in ubiquitin-dependent protein catabolic process
.ligase activity
.zinc ion binding
.ubiquitin-protein transferase activity
.cytoplasm
8 EBI-9675976,EBI-2865388 LHX4  
  .negative regulation of apoptotic process
.medial motor column neuron differentiation
.organ morphogenesis
  + 4 more...
.sequence-specific DNA binding
.zinc ion binding
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
ascites100
blood49
bone83
bone marrow61
brain26
cervix61
embryonic tissue14
eye57
heart44
intestine51
kidney42
larynx42
liver53
lung32
lymph90
lymph node22
mammary gland26
mouth15
muscle75
ovary68
pancreas60
pituitary gland60
placenta7
prostate31
skin9
stomach20
testis4
thyroid42
tonsil58
uterus34
Health State
TissuesTPM*
normal26
breast (mammary gland) tumor10
cervical tumor28
chondrosarcoma48
colorectal tumor53
gastrointestinal tumor67
germ cell tumor26
glioma83
head and neck tumor29
kidney tumor72
leukemia52
liver tumor62
lung tumor48
lymphoma55
ovarian tumor52
pancreatic tumor66
primitive neuroectodermal tumor of the CNS78
prostate cancer38
retinoblastoma43
skin tumor7
soft tissue/muscle tissue tumor39
uterine tumor22
Developmental Stage
TissuesTPM*
adult35
embryoid body14
fetus21
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue12.6
adrenal gland18.4
appendix21.3
bone marrow23.7
cerebral cortex31
colon18.8
duodenum13.5
esophagus16.4
gallbladder12.3
heart muscle44.6
kidney19.1
liver17.8
lung11.4
lymph node34.7
ovary20.9
pancreas10.7
placenta10.1
prostate19.8
salivary gland17.8
skin8.8
small intestine11.7
spleen16.2
stomach19.4
testis10.9
thyroid gland18.5
urinary bladder16
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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