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> Protein (NX_Q9BVK8)
Protein (NX_Q9BVK8)
Protein
Gene SymbolTMEM147 to neXtProt (NX_Q9BVK8)
DescriptionTransmembrane protein 147
Chromosome19
Location19q13.12 (36036497 ~ 36038428) to Ensembl
Sequene Features : Isoforms 2, Variants 22, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.protein destabilization .N/A .integral component of membrane
.endoplasmic reticulum membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 22 0
2014-09-19protein level
2 13 0
2014-05-27protein level
2 13 0
2014-02-25protein level
2 13 0
2013-12-09protein level
2 10 0
2013-11-01protein level
2 10 0
2013-09-12protein level
2 10 0
2013-08-17protein level
2 10 0
2013-07-15protein level
1 6 0
2013-06-11protein level
1 6 0
2013-02-12protein level
1 4 0
2012-12-20protein level
1 4 0
2012-10-30protein level
1 5 0
2012-10-07protein level
1 5 0
2012-08-24protein level
1 4 0
2012-07-28protein level
1 4 0
2012-06-08protein level
1 9 0
2012-05-07protein level
1 9 0
2012-04-10protein level
1 9 0
2012-01-13protein level
1 11 0
2011-12-20protein level
1 11 0
2011-11-11protein level
1 11 0
2011-08-23protein level
1 11 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9BVK8-1
3 8 0 25243.8139
NX_Q9BVK8-2
0 8 0 19530.1049
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-348587,EBI-10173166 LDLRAD1  
  .N/A .N/A .integral component of membrane
2 EBI-348587,EBI-7131783 SYNE4  
  .establishment of epithelial cell apical/basal polarity .N/A .LINC complex
.integral component of nuclear outer membrane
3 EBI-348587,EBI-6942903 CREB3L1  
  .positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
.negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
.extracellular matrix constituent secretion
  + 3 more...
.transcription regulatory region DNA binding
.sequence-specific DNA binding
.cAMP response element binding
  + 2 more...
.integral component of membrane
.endoplasmic reticulum membrane
.endoplasmic reticulum
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
adrenal gland91
ascites150
blood32
bone13
brain38
cervix41
connective tissue26
ear62
embryonic tissue61
eye76
intestine90
kidney33
larynx85
liver38
lung44
lymph node22
mammary gland46
muscle28
ovary137
pancreas149
pituitary gland60
placenta24
prostate31
skin128
spleen56
stomach31
testis2
thymus12
thyroid107
tonsil58
uterus60
Health State
TissuesTPM*
normal38
adrenal tumor158
bladder carcinoma113
breast (mammary gland) tumor75
cervical tumor57
chondrosarcoma36
colorectal tumor88
gastrointestinal tumor92
germ cell tumor22
glioma102
head and neck tumor44
kidney tumor29
leukemia21
liver tumor83
lung tumor58
lymphoma13
non-neoplasia20
ovarian tumor144
pancreatic tumor209
primitive neuroectodermal tumor of the CNS110
prostate cancer19
retinoblastoma64
skin tumor111
soft tissue/muscle tissue tumor23
uterine tumor77
Developmental Stage
TissuesTPM*
adult47
embryoid body42
blastocyst48
fetus26
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue45.2
adrenal gland66.4
appendix35.7
bone marrow28.2
cerebral cortex25.4
colon52.9
duodenum37
esophagus57.8
gallbladder41.5
heart muscle51.8
kidney64
liver20.5
lung40.3
lymph node30.7
ovary46.9
pancreas67.2
placenta41
prostate38.9
salivary gland43.5
skin60.4
small intestine29.7
spleen32.3
stomach38.7
testis49
thyroid gland76.1
urinary bladder48.3
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*613585, gene) Transmembrane protein 147; TMEM147OMIM


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