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> Protein (NX_Q9BVV7)
Protein (NX_Q9BVV7)
Protein
Gene SymbolTIMM21 to neXtProt (NX_Q9BVV7)
DescriptionMitochondrial import inner membrane translocase subunit Tim21
Chromosome18
Location18q22.3 (71815746 ~ 71826197) to Ensembl
Sequene Features : Isoforms 1, Variants 15, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cellular protein metabolic process
.mitochondrial respiratory chain complex IV assembly
.mitochondrial respiratory chain complex I assembly
  + 2 more...
.N/A .integral component of membrane
.mitochondrial inner membrane presequence translocase complex
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 15 0
2014-09-19protein level
1 26 0
2014-05-27protein level
1 26 0
2014-02-25protein level
1 26 0
2013-12-09protein level
1 17 0
2013-11-01protein level
1 17 0
2013-09-12protein level
1 17 0
2013-08-17protein level
1 17 0
2013-07-15protein level
1 14 0
2013-06-11protein level
1 14 0
2013-02-12protein level
1 8 0
2012-12-20protein level
1 9 0
2012-10-30protein level
1 11 0
2012-10-07protein level
1 11 0
2012-08-24protein level
1 10 0
2012-07-28protein level
1 10 0
2012-06-08protein level
1 11 0
2012-05-07protein level
1 10 0
2012-04-10protein level
1 10 0
2012-01-13protein level
1 3 0
2011-12-20protein level
1 3 0
2011-11-11protein level
1 3 0
2011-08-23protein level
1 3 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9BVV7-1
12 0 0 28184.7105
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-6570759,EBI-1047996 TIMM23  
  .cellular protein metabolic process
.protein targeting to mitochondrion
.P-P-bond-hydrolysis-driven protein transmembrane transporter activity .integral component of mitochondrial inner membrane
.mitochondrial intermembrane space
.mitochondrial inner membrane presequence translocase complex
  + 2 more...
2 EBI-6570759,EBI-2117234 MT-CO1  
  .hydrogen ion transmembrane transport
.small molecule metabolic process
.cellular metabolic process
  + 5 more...
.heme binding
.iron ion binding
.cytochrome-c oxidase activity
.respiratory chain complex IV
.integral component of membrane
.mitochondrial respiratory chain complex IV
.mitochondrial inner membrane
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
adrenal gland30
ascites25
bladder33
blood57
bone13
bone marrow61
brain21
cervix103
connective tissue26
embryonic tissue37
eye47
heart55
intestine21
kidney94
liver38
lung35
lymph22
lymph node11
mammary gland19
muscle28
ovary19
pancreas37
parathyroid48
pharynx147
pituitary gland60
placenta17
prostate42
skin4
stomach31
testis9
thyroid107
uterus30
Health State
TissuesTPM*
normal40
adrenal tumor79
breast (mammary gland) tumor10
cervical tumor57
chondrosarcoma36
colorectal tumor8
gastrointestinal tumor16
germ cell tumor37
glioma9
head and neck tumor37
kidney tumor14
leukemia21
liver tumor20
lung tumor19
lymphoma13
non-neoplasia20
ovarian tumor13
pancreatic tumor76
primitive neuroectodermal tumor of the CNS15
prostate cancer77
retinoblastoma86
skin tumor7
uterine tumor55
Developmental Stage
TissuesTPM*
adult25
embryoid body14
fetus50
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue18.2
adrenal gland19.7
appendix18.3
bone marrow10.1
cerebral cortex19.4
colon22.5
duodenum21.7
esophagus17.4
gallbladder12.7
heart muscle55.2
kidney26.7
liver13.9
lung13.1
lymph node19
ovary20.7
pancreas6.2
placenta17.3
prostate19.4
salivary gland13.7
skin15.2
small intestine17.5
spleen16.8
stomach13.6
testis12.3
thyroid gland21.8
urinary bladder21
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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