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> Protein (NX_Q9BW62)
Protein (NX_Q9BW62)
Protein
Gene SymbolKATNAL1 to neXtProt (NX_Q9BW62)
DescriptionKatanin p60 ATPase-containing subunit A-like 1
Chromosome13
Location13q12.3 (30776767 ~ 30881621) to Ensembl
Sequene Features : Isoforms 1, Variants 60, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.microtubule severing
.cytoplasmic microtubule organization
.metabolic process
.spermatogenesis
.microtubule-severing ATPase activity
.ATP binding
.microtubule
.cytoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 60 1
2014-09-19protein level
1 50 1
2014-05-27protein level
1 50 2
2014-02-25protein level
1 49 2
2013-12-09protein level
1 40 2
2013-11-01protein level
1 40 1
2013-09-12protein level
1 40 0
2013-08-17protein level
1 40 0
2013-07-15protein level
1 28 0
2013-06-11protein level
1 28 0
2013-02-12protein level
1 8 0
2012-12-20protein level
1 9 0
2012-10-30protein level
1 13 0
2012-10-07protein level
1 13 0
2012-08-24protein level
1 10 0
2012-07-28protein level
1 10 0
2012-06-08protein level
1 10 0
2012-05-07protein level
1 10 0
2012-04-10protein level
1 10 0
2012-01-13protein level
1 5 0
2011-12-20protein level
1 5 0
2011-11-11protein level
1 5 0
2011-08-23transcript level
1 5 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9BW62-1
24 0 4 55357.068
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-743591,EBI-711311 COX17  
  .heart development
.brain development
.copper ion transport
.generation of precursor metabolites and energy
.copper chaperone activity
.copper ion binding
.mitochondrial intermembrane space
.mitochondrion
.cytoplasm
2 EBI-743591,EBI-747107 SIAH1  
  .positive regulation of intrinsic apoptotic signaling pathway
.neuron apoptotic process
.proteasome-mediated ubiquitin-dependent protein catabolic process
  + 11 more...
.ubiquitin protein ligase activity
.identical protein binding
.ligase activity
  + 3 more...
.beta-catenin destruction complex
.plasma membrane
.cytosol
  + 3 more...
3 EBI-743591,EBI-1104570 CEP57L1  
  .microtubule anchoring .N/A .microtubule
.microtubule organizing center
.cytoplasm
4 EBI-743591,EBI-715394 KATNBL1  
  .N/A .N/A .nucleolus
5 EBI-743591,EBI-949319 KLC4  
  .N/A .microtubule motor activity .microtubule
.kinesin complex
.cytoplasm
6 EBI-743591,EBI-8643161 C1orf109  
  .N/A .N/A .N/A
7 EBI-743591,EBI-10320266 ZNF69  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood8
bone69
brain10
connective tissue20
ear124
embryonic tissue23
kidney9
liver14
lung11
lymph node122
mammary gland52
muscle28
nerve64
parathyroid48
pharynx24
prostate5
salivary gland49
skin28
spleen18
testis41
thymus12
trachea19
uterus12
vascular19
Health State
TissuesTPM*
normal21
chondrosarcoma96
gastrointestinal tumor8
germ cell tumor26
glioma18
leukemia21
liver tumor20
primitive neuroectodermal tumor of the CNS15
prostate cancer9
skin tumor7
Developmental Stage
TissuesTPM*
adult17
embryoid body57
neonate64
fetus34
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue7.7
adrenal gland4.2
appendix5.1
bone marrow3.8
cerebral cortex9.6
colon2.8
duodenum1.2
esophagus5.9
gallbladder4.2
heart muscle13.8
kidney3.9
liver2.4
lung4.9
lymph node6.3
ovary4.1
placenta2.2
prostate4
salivary gland1.5
skin2.2
small intestine1.9
spleen3.4
stomach2
testis18.5
thyroid gland3
urinary bladder5.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*614764, gene) Katanin p60 subunit a-like 1; KATNAL1OMIM


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