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> Protein (NX_Q9BWC9)
Protein (NX_Q9BWC9)
Protein
Gene SymbolCCDC106 to neXtProt (NX_Q9BWC9)
DescriptionCoiled-coil domain-containing protein 106
Chromosome19
Location19q13.42 (56152428 ~ 56164527) to Ensembl
Sequene Features : Isoforms 1, Variants 37, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .cytoplasm
.nucleolus
.nucleoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 37 0
2014-09-19protein level
1 31 0
2014-05-27protein level
1 31 0
2014-02-25protein level
1 31 0
2013-12-09protein level
1 25 0
2013-11-01protein level
1 24 0
2013-09-12protein level
1 24 0
2013-08-17protein level
1 24 0
2013-07-15protein level
1 16 0
2013-06-11protein level
1 16 0
2013-02-12protein level
1 8 0
2012-12-20protein level
1 8 0
2012-10-30protein level
1 8 0
2012-10-07protein level
1 8 0
2012-08-24protein level
1 7 0
2012-07-28protein level
1 7 0
2012-06-08protein level
1 7 0
2012-05-07protein level
1 5 0
2012-04-10protein level
1 5 0
2012-01-13protein level
1 3 0
2011-12-20protein level
1 3 0
2011-11-11protein level
1 3 0
2011-08-23protein level
1 3 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9BWC9-1
11 0 0 32012.3413
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-711501,EBI-366083 TP53  
  .positive regulation of intrinsic apoptotic signaling pathway
.positive regulation of reactive oxygen species metabolic process
.negative regulation of reactive oxygen species metabolic process
  + 99 more...
.protein phosphatase 2A binding
.chaperone binding
.protein N-terminus binding
  + 27 more...
.protein complex
.PML body
.nuclear matrix
  + 11 more...
2 EBI-711501,EBI-492498 ATF4  
  .positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
.negative regulation of oxidative stress-induced neuron death
.intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
  + 21 more...
.protein heterodimerization activity
.transcription regulatory region DNA binding
.sequence-specific DNA binding
  + 9 more...
.CHOP-ATF4 complex
.ATF1-ATF4 transcription factor complex
.ATF4-CREB1 transcription factor complex
  + 8 more...
3 EBI-711501,EBI-10175124 FAM9B  
  .spermatid development .N/A .nucleoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
ascites25
blood32
bone13
brain39
cervix144
connective tissue13
embryonic tissue42
eye33
heart22
intestine8
kidney4
larynx127
liver4
lung2
lymph node22
mammary gland26
muscle47
nerve64
ovary9
pancreas14
placenta7
prostate21
salivary gland394
skin47
spleen18
stomach10
testis6
thyroid21
uterus21
Health State
TissuesTPM*
normal20
breast (mammary gland) tumor21
cervical tumor86
chondrosarcoma24
gastrointestinal tumor16
germ cell tumor11
glioma18
head and neck tumor89
leukemia31
lung tumor9
lymphoma69
non-neoplasia20
pancreatic tumor28
primitive neuroectodermal tumor of the CNS47
prostate cancer38
retinoblastoma64
skin tumor79
soft tissue/muscle tissue tumor63
uterine tumor22
Developmental Stage
TissuesTPM*
adult21
embryoid body42
blastocyst48
fetus23
infant42
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue8.8
adrenal gland10.9
appendix5.2
bone marrow1.7
cerebral cortex14.3
colon4.4
duodenum4
esophagus3.1
gallbladder7
heart muscle9
kidney16.1
liver6.4
lung6.5
lymph node8.5
ovary6.4
pancreas3.3
placenta4.1
prostate9.4
salivary gland7.2
skin4.6
small intestine3.8
spleen9.1
stomach6.4
testis12.4
thyroid gland6.1
urinary bladder7.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*613478, gene) Coiled-coil domain-containing protein 106; CCDC106OMIM


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