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> Protein (NX_Q9BXS5)
Protein (NX_Q9BXS5)
Protein
Gene SymbolAP1M1 to neXtProt (NX_Q9BXS5)
DescriptionAP-1 complex subunit mu-1
Chromosome19
Location19p13.11 (16308389 ~ 16346160) to Ensembl
Sequene Features : Isoforms 2, Variants 44, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.membrane organization
.regulation of defense response to virus by virus
.endosome to melanosome transport
  + 5 more...
.N/A .extracellular exosome
.trans-Golgi network membrane
.clathrin-coated endocytic vesicle membrane
  + 6 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 44 7
2014-09-19protein level
2 36 7
2014-05-27protein level
2 36 9
2014-02-25protein level
2 35 9
2013-12-09protein level
2 29 9
2013-11-01protein level
2 28 7
2013-09-12protein level
2 28 7
2013-08-17protein level
2 28 7
2013-07-15protein level
2 17 3
2013-06-11protein level
2 17 3
2013-02-12protein level
2 9 6
2012-12-20protein level
2 9 5
2012-10-30protein level
2 9 6
2012-10-07protein level
2 9 3
2012-08-24protein level
2 7 3
2012-07-28protein level
2 7 3
2012-06-08protein level
2 8 3
2012-05-07protein level
2 3 3
2012-04-10protein level
2 3 3
2012-01-13protein level
1 4 3
2011-12-20protein level
1 4 3
2011-11-11protein level
1 4 3
2011-08-23protein level
1 4 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9BXS5-1
1 19 4 48555.9189
NX_Q9BXS5-2
2 19 4 49808.5507
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-541426,EBI-740718 ZBTB43  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
2 EBI-541426,EBI-10176632 ZBTB14  
  .negative regulation of transcription, DNA-templated
.transcription from RNA polymerase II promoter
.negative regulation of transcription from RNA polymerase II promoter
.metal ion binding
.transcription regulatory region DNA binding
.sequence-specific DNA binding
  + 2 more...
.cytoplasm
.nucleoplasm
.nucleus
3 EBI-541426,EBI-740738 LDOC1  
  .negative regulation of cell proliferation .N/A .nucleolus
.nucleus
4 EBI-541426,EBI-1372759 ETV6  
  .hematopoietic stem cell proliferation
.cell differentiation
.transcription from RNA polymerase II promoter
  + 2 more...
.protein domain specific binding
.sequence-specific DNA binding transcription factor activity
.RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
  + 4 more...
.cytoplasm
.nucleolus
5 EBI-541426,EBI-740459 FXR2  
  .negative regulation of translation
.positive regulation of defense response to virus by host
.poly(A) RNA binding
.identical protein binding
.mRNA binding
.RNA binding
.extracellular exosome
.cytosolic large ribosomal subunit
.membrane
  + 3 more...
6 EBI-541426,EBI-10172290 KRTAP10-7  
  .N/A .identical protein binding .keratin filament
7 EBI-541426,EBI-745305 IKZF1  
  .retina development in camera-type eye
.positive regulation of NK T cell differentiation
.Peyer's patch development
  + 17 more...
.metal ion binding
.sequence-specific DNA binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.protein complex
.cytoplasm
.pericentric heterochromatin
.nucleus
8 EBI-541426,EBI-747024 MTF1  
  .transition metal ion homeostasis
.response to cadmium ion
.positive regulation of transcription from RNA polymerase II promoter
  + 3 more...
.metal ion binding
.transcription coactivator activity
.sequence-specific DNA binding transcription factor activity
  + 5 more...
.nucleoplasm
.nucleus
9 EBI-541426,EBI-357849 TNIP1  
  .modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade
.negative regulation of ERK1 and ERK2 cascade
.positive regulation of inflammatory response
  + 9 more...
.mitogen-activated protein kinase binding .cytoplasm
.nucleus
.intracellular
10 EBI-541426,EBI-747225 RUNDC3A  
  .small GTPase mediated signal transduction .GTPase regulator activity
.guanylate cyclase activator activity
.plasma membrane
.cytosol
11 EBI-541426,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
12 EBI-541426,EBI-948630 DZIP3  
  .protein polyubiquitination .poly(A) RNA binding
.polyubiquitin binding
.phosphatase binding
  + 4 more...
.cytoplasm
13 EBI-541426,EBI-713786 PHC2  
  .cellular protein metabolic process
.post-translational protein modification
.protein sumoylation
  + 2 more...
.identical protein binding
.zinc ion binding
.DNA binding
.PRC1 complex
.PcG protein complex
.nucleoplasm
  + 2 more...
14 EBI-541426,EBI-10181988 CEP57L1  
  .microtubule anchoring .N/A .microtubule
.microtubule organizing center
.cytoplasm
15 EBI-541426,EBI-10175124 FAM9B  
  .spermatid development .N/A .nucleoplasm
16 EBI-541426,EBI-5658292 ZBTB44  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
17 EBI-541426,EBI-742740 ZBTB8A  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
18 EBI-541426,EBI-10178036 SDCCAG3  
  .retrograde transport, endosome to plasma membrane
.cell division
.regulation of cytokinesis
  + 2 more...
.N/A .recycling endosome
.midbody
.early endosome
.endosome
19 EBI-541426,EBI-740711 TIFA  
  .I-kappaB kinase/NF-kappaB signaling .N/A .N/A
20 EBI-541426,EBI-743290 HOOK2  
  .early endosome to late endosome transport
.protein transport
.endosome to lysosome transport
  + 3 more...
.identical protein binding .FHF complex
.microtubule
.centrosome
21 EBI-541426,EBI-10171633 PNMA5  
  .positive regulation of apoptotic process .identical protein binding .N/A
22 EBI-541426,EBI-741037 LZTS2  
  .negative regulation of protein localization to nucleus
.negative regulation of canonical Wnt signaling pathway
.spindle midzone assembly
  + 7 more...
.N/A .midbody
.microtubule
.centrosome
.cytoplasm
23 EBI-541426,EBI-2212028 SSX2IP  
  .regulation of cell motility
.centrosome organization
.cilium assembly
  + 3 more...
.N/A .protein complex
.ciliary basal body
.centriolar satellite
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland212
ascites326
bladder66
blood179
bone41
bone marrow82
brain241
cervix103
connective tissue174
embryonic tissue93
esophagus148
eye110
heart78
intestine125
kidney218
liver116
lung137
lymph1038
lymph node55
mammary gland92
mouth45
muscle18
ovary49
pancreas14
pituitary gland121
placenta109
prostate47
salivary gland49
skin260
spleen168
stomach73
testis250
thymus213
thyroid214
tonsil117
trachea135
uterus142
vascular154
Health State
TissuesTPM*
normal156
breast (mammary gland) tumor128
cervical tumor115
chondrosarcoma181
colorectal tumor97
esophageal tumor173
gastrointestinal tumor143
germ cell tumor216
glioma270
head and neck tumor89
kidney tumor217
leukemia148
liver tumor218
lung tumor223
lymphoma664
non-neoplasia113
ovarian tumor78
pancreatic tumor19
primitive neuroectodermal tumor of the CNS314
prostate cancer48
skin tumor311
soft tissue/muscle tissue tumor55
uterine tumor44
Developmental Stage
TissuesTPM*
adult114
embryoid body85
blastocyst113
neonate354
fetus116
infant212
juvenile215
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue30.5
adrenal gland27
appendix30.2
bone marrow32.3
cerebral cortex35.5
colon13.6
duodenum29
esophagus18.2
gallbladder21.3
heart muscle26.9
kidney32.1
liver28.1
lung30.3
lymph node33.4
ovary25
pancreas8.7
placenta26.1
prostate15.6
salivary gland11.4
skin15.5
small intestine19.2
spleen33
stomach15.6
testis58.2
thyroid gland15.2
urinary bladder27.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603535, gene) Adaptor-related protein complex 1, mu-1 subunit; AP1M1OMIM


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