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> Protein (NX_Q9BXW4)
Protein (NX_Q9BXW4)
Protein
Gene SymbolMAP1LC3C to neXtProt (NX_Q9BXW4)
DescriptionMicrotubule-associated proteins 1A/1B light chain 3C
Chromosome1
Location1q43 (242158792 ~ 242162375) to Ensembl
Sequene Features : Isoforms 1, Variants 27, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.membrane fusion
.nucleophagy
.cellular response to nitrogen starvation
  + 2 more...
.microtubule binding .cytoplasmic vesicle
.organelle membrane
.extrinsic component of membrane
  + 6 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 27 1
2014-09-19protein level
1 25 1
2014-05-27protein level
1 25 1
2014-02-25protein level
1 24 1
2013-12-09protein level
1 23 1
2013-11-01protein level
1 22 1
2013-09-12protein level
1 22 1
2013-08-17protein level
1 22 1
2013-07-15protein level
1 13 1
2013-06-11protein level
1 13 1
2013-02-12protein level
1 5 1
2012-12-20protein level
1 5 1
2012-10-30protein level
1 6 1
2012-10-07protein level
1 6 1
2012-08-24protein level
1 3 1
2012-07-28protein level
1 3 1
2012-06-08protein level
1 4 1
2012-05-07protein level
1 4 1
2012-04-10protein level
1 4 1
2012-01-13protein level
1 4 1
2011-12-20protein level
1 4 1
2011-11-11protein level
1 4 1
2011-08-23protein level
1 4 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9BXW4-1
8 0 0 16840.6673
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2603996,EBI-356424 IPO5  
  .cellular response to amino acid stimulus
.positive regulation of protein import into nucleus
.negative regulation of GTPase activity
  + 3 more...
.poly(A) RNA binding
.protein transporter activity
.Ran GTPase binding
.GTPase inhibitor activity
.intracellular membrane-bounded organelle
.nuclear membrane
.membrane
  + 6 more...
2 EBI-2603996,EBI-2946991 TECPR2  
  .autophagy .N/A .N/A
3 EBI-2603996,EBI-307133 GBAS  
  .negative regulation of ATP citrate synthase activity
.ATP biosynthetic process
.oxidative phosphorylation
.N/A .membrane
.integral component of plasma membrane
.mitochondrion
4 EBI-2603996,EBI-908831 ULK1  
  .regulation of neurotrophin TRK receptor signaling pathway
.axon extension
.negative regulation of collateral sprouting
  + 15 more...
.protein complex binding
.Rab GTPase binding
.ATP binding
.protein serine/threonine kinase activity
.extrinsic component of autophagic vacuole membrane
.extrinsic component of pre-autophagosomal structure membrane
.extrinsic component of omegasome membrane
  + 9 more...
5 EBI-2603996,EBI-992580 STK3  
  .positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
.hepatocyte apoptotic process
.negative regulation of canonical Wnt signaling pathway
  + 25 more...
.protein dimerization activity
.protein serine/threonine kinase activator activity
.ATP binding
  + 4 more...
.cytosol
.cytoplasm
.nucleus
6 EBI-2603996,EBI-307104 SQSTM1  
  .activation of mitophagy in response to mitochondrial depolarization
.apoptotic signaling pathway
.protein heterooligomerization
  + 20 more...
.ubiquitin binding
.identical protein binding
.SH2 domain binding
  + 5 more...
.extracellular exosome
.cytoplasmic vesicle
.PML body
  + 11 more...
7 EBI-2603996,EBI-742698 NBR1  
  .protein oligomerization
.negative regulation of osteoblast differentiation
.regulation of stress-activated MAPK cascade
  + 2 more...
.mitogen-activated protein kinase binding
.ubiquitin binding
.zinc ion binding
.extracellular exosome
.M band
.cytoplasmic vesicle
  + 6 more...
8 EBI-2603996,EBI-1054743 SF3A1  
  .gene expression
.RNA splicing
.mRNA processing
  + 3 more...
.poly(A) RNA binding
.RNA binding
.catalytic step 2 spliceosome
.U2-type prespliceosome
.U2 snRNP
  + 3 more...
9 EBI-2603996,EBI-535909 ATG16L1  
  .protein homooligomerization
.negative stranded viral RNA replication
.protein transport
.autophagic vacuole assembly
.identical protein binding .pre-autophagosomal structure membrane
.axoneme
.autophagic vacuole
.autophagic vacuole membrane
10 EBI-2603996,EBI-2514778 KBTBD6  
  .N/A .N/A .N/A
11 EBI-2603996,EBI-1569256 WDFY3  
  .aggrephagy
.positive regulation of macroautophagy
.endosomal transport
.metal ion binding
.1-phosphatidylinositol binding
.beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity
.extrinsic component of autophagic vacuole membrane
.nuclear membrane
.extrinsic component of membrane
  + 5 more...
12 EBI-2603996,EBI-1044009 NEK9  
  .cell division
.mitotic nuclear envelope disassembly
.mitotic nuclear division
  + 2 more...
.metal ion binding
.protein kinase binding
.ATP binding
.protein serine/threonine kinase activity
.cytosol
.nucleus
13 EBI-2603996,EBI-473695 KBTBD7  
  .N/A .N/A .N/A
14 EBI-2603996,EBI-367390 RASSF5  
  .regulation of protein localization to nucleus
.intracellular signal transduction
.positive regulation of protein ubiquitination
  + 2 more...
.metal ion binding .microtubule
.cytoplasm
.nucleus
15 EBI-2603996,EBI-2946907 DYX1C1  
  .regulation of proteasomal protein catabolic process
.inner dynein arm assembly
.outer dynein arm assembly
  + 4 more...
.estrogen receptor binding .plasma membrane
.cytoplasm
.nucleus
16 EBI-2603996,EBI-2869338 FYCO1  
  .plus-end-directed vesicle transport along microtubule .metal ion binding .cytoplasmic vesicle
.integral component of membrane
.membrane
  + 3 more...
17 EBI-2603996,EBI-2946739 ATG101  
  .autophagic vacuole assembly .identical protein binding
.protein complex binding
.pre-autophagosomal structure
18 EBI-2603996,EBI-747805 UBA5  
  .protein polyufmylation
.protein ufmylation
.response to endoplasmic reticulum stress
.regulation of intracellular estrogen receptor signaling pathway
.UFM1 activating enzyme activity
.metal ion binding
.ATP binding
.intracellular membrane-bounded organelle
.cytosol
.cytoplasm
.nucleus
19 EBI-2603996,EBI-367363 RASSF1  
  .negative regulation of cell cycle arrest
.protein stabilization
.positive regulation of protein ubiquitination
  + 3 more...
.protein N-terminus binding
.identical protein binding
.zinc ion binding
.microtubule cytoskeleton
.plasma membrane
.microtubule
  + 4 more...
20 EBI-2603996,EBI-2947180 TBC1D2B  
  .N/A .GTPase activator activity .N/A
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
embryonic tissue4
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue2.6
esophagus1.2
lung3.9
lymph node3.7
ovary2.3
placenta13
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*609605, gene) Microtubule-associated protein 1, light chain 3, gamma; MAP1LC3COMIM


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