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> Protein (NX_Q9BXY8)
Protein (NX_Q9BXY8)
Protein
Gene SymbolBEX2 to neXtProt (NX_Q9BXY8)
DescriptionProtein BEX2
ChromosomeX
LocationXq22.1 (102564274 ~ 102565974) to Ensembl
Sequene Features : Isoforms 2, Variants 18, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of cell cycle
.regulation of apoptotic process
.cell cycle
.apoptotic process
.N/A .cytoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 18 0
2014-09-19protein level
2 13 0
2014-05-27protein level
2 13 0
2014-02-25protein level
2 13 0
2013-12-09protein level
2 12 0
2013-11-01protein level
2 12 0
2013-09-12protein level
2 12 0
2013-08-17protein level
2 12 0
2013-07-15protein level
1 5 0
2013-06-11protein level
1 5 0
2013-02-12protein level
1 3 0
2012-12-20protein level
1 3 0
2012-10-30protein level
1 3 0
2012-10-07protein level
1 3 0
2012-08-24protein level
1 3 0
2012-07-28protein level
1 3 0
2012-06-08protein level
1 3 0
2012-05-07protein level
1 3 0
2012-04-10protein level
1 3 0
2012-01-13protein level
1 3 0
2011-12-20protein level
1 3 0
2011-11-11protein level
1 3 0
2011-08-23protein level
1 3 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9BXY8-1
0 2 1 15311.5711
NX_Q9BXY8-2
2 2 1 18707.1281
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-745073,EBI-5661036 FSD2  
  .N/A .N/A .N/A
2 EBI-745073,EBI-1047263 KRT38  
  .N/A .structural molecule activity .extracellular exosome
.intermediate filament
3 EBI-745073,EBI-719493 TRIM27  
  .negative regulation of viral release from host cell
.negative regulation of interleukin-2 secretion
.negative regulation of calcium ion import
  + 17 more...
.metal ion binding
.ligase activity
.zinc ion binding
  + 4 more...
.nuclear membrane
.PML body
.membrane
  + 6 more...
4 EBI-745073,EBI-739566 KRT15  
  .activation of mitophagy in response to mitochondrial depolarization
.epidermis development
.scaffold protein binding
.structural constituent of cytoskeleton
.extracellular exosome
.intermediate filament
.nucleus
5 EBI-745073,EBI-3958099 KRTAP5-9  
  .epidermis development .N/A .keratin filament
6 EBI-745073,EBI-10178634 MAGEA11  
  .N/A .N/A .cytoplasm
.nucleoplasm
.nucleus
7 EBI-745073,EBI-10171774 KRTAP10-8  
  .N/A .N/A .keratin filament
8 EBI-745073,EBI-355744 TRAF2  
  .positive regulation of extrinsic apoptotic signaling pathway
.regulation of extrinsic apoptotic signaling pathway via death domain receptors
.negative regulation of neuron death
  + 35 more...
.sphingolipid binding
.identical protein binding
.thioesterase binding
  + 10 more...
.IRE1-TRAF2-ASK1 complex
.TRAF2-GSTP1 complex
.membrane raft
  + 7 more...
9 EBI-745073,EBI-2340269 MKRN3  
  .protein ubiquitination .ligase activity
.zinc ion binding
.ribonucleoprotein complex
10 EBI-745073,EBI-359224 TRAF1  
  .regulation of extrinsic apoptotic signaling pathway
.positive regulation of NF-kappaB transcription factor activity
.signal transduction
  + 2 more...
.thioesterase binding
.ubiquitin protein ligase binding
.zinc ion binding
.tumor necrosis factor receptor binding
.cytoplasm
11 EBI-745073,EBI-739580 CALCOCO2  
  .response to interferon-gamma
.viral process
.protein homodimerization activity .perinuclear region of cytoplasm
.intracellular membrane-bounded organelle
.membrane
  + 4 more...
12 EBI-745073,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
13 EBI-745073,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
14 EBI-745073,EBI-302345 PNMA1  
  .positive regulation of apoptotic process
.inflammatory response to antigenic stimulus
.N/A .focal adhesion
.cytoplasm
.nucleolus
15 EBI-745073,EBI-739624 CEP70  
  .organelle organization
.mitotic cell cycle
.G2/M transition of mitotic cell cycle
.N/A .nuclear membrane
.cytosol
.centrosome
  + 2 more...
16 EBI-745073,EBI-2548751 MIPOL1  
  .N/A .N/A .nucleus
17 EBI-745073,EBI-741037 LZTS2  
  .negative regulation of protein localization to nucleus
.negative regulation of canonical Wnt signaling pathway
.spindle midzone assembly
  + 7 more...
.N/A .midbody
.microtubule
.centrosome
.cytoplasm
18 EBI-745073,EBI-3957793 PRDM14  
  .homeostasis of number of cells within a tissue
.regulation of DNA methylation
.negative regulation of fibroblast growth factor receptor signaling pathway
  + 11 more...
.metal ion binding
.methyltransferase activity
.DNA binding
.nucleoplasm
19 EBI-745073,EBI-2548012 BLZF1  
  .Golgi to plasma membrane protein transport
.cell proliferation
.Golgi organization
  + 3 more...
.ubiquitin protein ligase binding
.enzyme binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.Golgi lumen
.cytoplasm
.nucleoplasm
  + 2 more...
20 EBI-745073,EBI-2212028 SSX2IP  
  .regulation of cell motility
.centrosome organization
.cilium assembly
  + 3 more...
.N/A .protein complex
.ciliary basal body
.centriolar satellite
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites25
bladder33
brain117
embryonic tissue23
eye38
heart11
kidney18
liver9
lung35
mammary gland26
mouth15
ovary68
pancreas117
parathyroid97
pharynx24
pituitary gland181
placenta17
prostate31
skin4
stomach10
testis25
thymus12
thyroid107
uterus25
Health State
TissuesTPM*
normal33
adrenal tumor79
breast (mammary gland) tumor42
gastrointestinal tumor16
germ cell tumor26
glioma9
head and neck tumor22
kidney tumor43
liver tumor20
lung tumor9
ovarian tumor78
pancreatic tumor57
primitive neuroectodermal tumor of the CNS31
prostate cancer28
skin tumor7
soft tissue/muscle tissue tumor23
uterine tumor33
Developmental Stage
TissuesTPM*
adult24
embryoid body28
blastocyst16
fetus21
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue1.4
adrenal gland71.8
appendix7.5
bone marrow9.4
cerebral cortex126.4
colon8.7
duodenum3.7
esophagus5
gallbladder7.9
heart muscle11.2
kidney44.2
lung11.3
lymph node14.6
ovary52.1
pancreas13.1
placenta11.4
prostate21.2
salivary gland16.7
skin6.7
small intestine6.4
spleen13.6
stomach10.7
testis32.5
thyroid gland108.5
urinary bladder7.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*300691, gene) Brain-expressed x-linked gene 2; BEX2OMIM


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