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> Protein (NX_Q9BY27)
Protein (NX_Q9BY27)
Protein
Gene SymbolDGCR6L to neXtProt (NX_Q9BY27)
DescriptionProtein DGCR6L
Chromosome22
Location22q11.21 (20301799 ~ 20307603) to Ensembl
Sequene Features : Isoforms 1, Variants 13, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 13 0
2014-09-19protein level
1 12 0
2014-05-27protein level
1 12 0
2014-02-25protein level
1 12 0
2013-12-09protein level
1 10 0
2013-11-01protein level
1 10 0
2013-09-12protein level
1 10 0
2013-08-17protein level
1 10 0
2013-07-15protein level
1 8 0
2013-06-11protein level
1 8 0
2013-02-12protein level
1 4 0
2012-12-20protein level
1 4 0
2012-10-30protein level
1 5 0
2012-10-07protein level
1 5 0
2012-08-24protein level
1 5 0
2012-07-28protein level
1 5 0
2012-06-08protein level
1 6 0
2012-05-07protein level
1 6 0
2012-04-10protein level
1 6 0
2012-01-13protein level
1 7 0
2011-12-20protein level
1 7 0
2011-11-11protein level
1 7 0
2011-08-23protein level
1 7 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9BY27-1
3 0 6 24916.9333
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-742953,EBI-748597 CCDC67  
  .multi-ciliated epithelial cell differentiation
.de novo centriole assembly
.cell projection organization
.N/A .deuterosome
.cytoplasm
2 EBI-742953,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
3 EBI-742953,EBI-741037 LZTS2  
  .negative regulation of protein localization to nucleus
.negative regulation of canonical Wnt signaling pathway
.spindle midzone assembly
  + 7 more...
.N/A .midbody
.microtubule
.centrosome
.cytoplasm
4 EBI-742953,EBI-10182375 RIMBP3  
  .N/A .N/A .N/A
5 EBI-742953,EBI-10172526 MID2  
  .negative regulation of viral release from host cell
.positive regulation of NF-kappaB transcription factor activity
.positive regulation of sequence-specific DNA binding transcription factor activity
  + 6 more...
.phosphoprotein binding
.protein heterodimerization activity
.protein homodimerization activity
  + 3 more...
.extracellular exosome
.microtubule
.cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
bone41
bone marrow41
brain20
cervix41
connective tissue13
ear62
embryonic tissue37
eye28
heart11
intestine43
kidney71
liver29
lung65
lymph45
lymph node11
mammary gland6
muscle112
ovary49
pancreas32
parathyroid145
placenta14
prostate26
salivary gland148
skin23
spleen18
stomach31
testis18
thymus25
thyroid42
trachea19
uterus21
vascular38
Health State
TissuesTPM*
normal27
breast (mammary gland) tumor10
chondrosarcoma48
colorectal tumor53
gastrointestinal tumor33
germ cell tumor7
glioma55
head and neck tumor29
kidney tumor87
leukemia21
liver tumor62
lung tumor19
lymphoma41
non-neoplasia20
ovarian tumor52
pancreatic tumor28
primitive neuroectodermal tumor of the CNS15
prostate cancer28
skin tumor31
soft tissue/muscle tissue tumor63
uterine tumor11
Developmental Stage
TissuesTPM*
adult29
embryoid body57
blastocyst16
fetus44
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue18.4
adrenal gland21.6
appendix14.3
bone marrow18.9
cerebral cortex20.7
colon16.1
duodenum17
esophagus20.9
gallbladder20.2
heart muscle36.1
kidney36.8
liver30.8
lung21.9
lymph node22.8
ovary24.2
pancreas18.6
placenta12.4
prostate26
salivary gland33.1
skin26.7
small intestine18.8
spleen20.4
stomach19.7
testis65.5
thyroid gland33.1
urinary bladder20
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*609459, gene) Digeorge syndrome critical region gene 6-like; DGCR6LOMIM


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