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> Protein (NX_Q9BY43)
Protein (NX_Q9BY43)
Protein
Gene SymbolCHMP4A to neXtProt (NX_Q9BY43)
DescriptionCharged multivesicular body protein 4a
Chromosome14
Location14q12 (24678789 ~ 24683075) to Ensembl
Sequene Features : Isoforms 2, Variants 35, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of autophagic vacuole assembly
.negative regulation of neuron death
.membrane tubulation
  + 14 more...
.ATPase binding
.protein homodimerization activity
.identical protein binding
.lipid binding
.extracellular exosome
.late endosome membrane
.cytoplasmic vesicle membrane
  + 7 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 35 1
2014-09-19protein level
1 24 1
2014-05-27protein level
1 24 1
2014-02-25protein level
1 14 1
2013-12-09protein level
1 7 1
2013-11-01protein level
1 7 1
2013-09-12protein level
1 7 1
2013-08-17protein level
1 7 1
2013-07-15protein level
1 7 1
2013-06-11protein level
1 7 1
2013-02-12protein level
1 7 0
2012-12-20protein level
1 7 0
2012-10-30protein level
1 6 0
2012-10-07protein level
1 6 0
2012-08-24protein level
1 6 0
2012-07-28protein level
1 6 0
2012-06-08protein level
1 14 0
2012-05-07protein level
1 14 0
2012-04-10protein level
1 14 0
2012-01-13protein level
1 11 0
2011-12-20protein level
1 11 0
2011-11-11protein level
1 11 0
2011-08-23protein level
1 11 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9BY43-1
0 9 0 25082.7485
NX_Q9BY43-2
2 9 0 29785.1698
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-747981,EBI-745392 SYT17  
  .positive regulation of dendrite extension
.calcium ion-dependent exocytosis of neurotransmitter
.regulation of calcium ion-dependent exocytosis
  + 2 more...
.clathrin binding
.syntaxin binding
.calcium-dependent phospholipid binding
.calcium ion binding
.plasma membrane
.trans-Golgi network
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
ascites50
bladder66
blood32
bone69
brain19
cervix20
connective tissue13
embryonic tissue51
esophagus49
eye23
heart11
intestine30
kidney28
larynx85
liver24
lung62
lymph203
lymph node11
mammary gland59
muscle28
nerve128
ovary118
pancreas32
pharynx171
placenta14
prostate68
salivary gland98
skin28
spleen56
stomach41
testis20
thymus12
thyroid21
tonsil58
umbilical cord72
uterus38
Health State
TissuesTPM*
normal25
adrenal tumor79
bladder carcinoma56
breast (mammary gland) tumor75
cervical tumor28
chondrosarcoma96
colorectal tumor35
esophageal tumor57
gastrointestinal tumor33
germ cell tumor18
head and neck tumor44
kidney tumor87
liver tumor20
lung tumor116
lymphoma207
non-neoplasia10
ovarian tumor105
pancreatic tumor47
primitive neuroectodermal tumor of the CNS15
prostate cancer38
retinoblastoma21
skin tumor31
soft tissue/muscle tissue tumor23
uterine tumor77
Developmental Stage
TissuesTPM*
adult34
embryoid body57
blastocyst65
neonate32
fetus12
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue67.7
adrenal gland45.2
appendix65.1
bone marrow40.6
cerebral cortex34.1
colon73
duodenum46.9
esophagus64.7
gallbladder53.8
heart muscle47.5
kidney48.7
liver37
lung46.5
lymph node97.1
ovary37.6
pancreas23.6
placenta40.4
prostate53.1
salivary gland27.8
skin63
small intestine53.2
spleen69.7
stomach54.8
testis26.6
thyroid gland60.6
urinary bladder64.8
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*610051, gene) Chmp family, member 4a; CHMP4AOMIM


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