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> Protein (NX_Q9BY50)
Protein (NX_Q9BY50)
Protein
Gene SymbolSEC11C to neXtProt (NX_Q9BY50)
DescriptionSignal peptidase complex catalytic subunit SEC11C
Chromosome18
Location18q21.32 (56806709 ~ 56826068) to Ensembl
Sequene Features : Isoforms 1, Variants 16, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of insulin secretion
.cellular protein metabolic process
.gene expression
  + 3 more...
.serine-type peptidase activity .integral component of membrane
.endoplasmic reticulum membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 16 4
2014-09-19protein level
1 13 4
2014-05-27protein level
1 13 4
2014-02-25protein level
1 13 4
2013-12-09protein level
1 10 4
2013-11-01protein level
1 9 1
2013-09-12protein level
1 9 1
2013-08-17protein level
1 9 1
2013-07-15protein level
1 5 0
2013-06-11protein level
1 5 0
2013-02-12protein level
1 2 0
2012-12-20protein level
1 3 0
2012-10-30protein level
1 5 0
2012-10-07protein level
1 5 0
2012-08-24protein level
1 5 0
2012-07-28protein level
1 5 0
2012-06-08protein level
1 3 0
2012-05-07protein level
1 3 0
2012-04-10protein level
1 3 0
2012-01-13protein level
1 6 0
2011-12-20protein level
1 6 0
2011-11-11protein level
1 6 0
2011-08-23protein level
1 6 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9BY50-1
9 0 0 21528.3895
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites25
bladder33
blood24
bone41
brain37
connective tissue26
ear62
embryonic tissue4
eye33
intestine21
kidney4
liver24
lung50
lymph node22
mammary gland185
muscle28
ovary9
pancreas234
pituitary gland242
placenta7
prostate94
skin28
stomach20
testis11
thymus37
uterus51
Health State
TissuesTPM*
normal36
adrenal tumor79
breast (mammary gland) tumor279
colorectal tumor17
gastrointestinal tumor25
germ cell tumor11
glioma9
head and neck tumor7
leukemia21
liver tumor31
lung tumor38
lymphoma13
non-neoplasia31
ovarian tumor39
pancreatic tumor95
primitive neuroectodermal tumor of the CNS15
prostate cancer115
retinoblastoma64
skin tumor31
soft tissue/muscle tissue tumor39
uterine tumor33
Developmental Stage
TissuesTPM*
adult44
embryoid body14
fetus44
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue20.5
adrenal gland76.6
appendix88
bone marrow38.8
cerebral cortex96.9
colon88.4
duodenum110.1
esophagus39.3
gallbladder45.2
heart muscle21
kidney70.7
liver122.7
lung50.6
lymph node93.4
ovary25.8
pancreas151.9
placenta27.7
prostate241
salivary gland248.7
skin24.7
small intestine86.1
spleen66.1
stomach136.9
testis30.8
thyroid gland132.4
urinary bladder80.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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