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> Protein (NX_Q9BYQ4)
Protein (NX_Q9BYQ4)
Protein
Gene SymbolKRTAP9-2 to neXtProt (NX_Q9BYQ4)
DescriptionKeratin-associated protein 9-2
Chromosome17
Location17q21.2 (39382900 ~ 39383904) to Ensembl
Sequene Features : Isoforms 1, Variants 33, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .keratin filament
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01transcript level
1 33 0
2014-09-19transcript level
1 29 0
2014-05-27transcript level
1 29 0
2014-02-25transcript level
1 29 0
2013-12-09transcript level
1 26 0
2013-11-01transcript level
1 26 0
2013-09-12transcript level
1 26 0
2013-08-17transcript level
1 26 0
2013-07-15transcript level
1 20 0
2013-06-11transcript level
1 20 0
2013-02-12transcript level
1 14 0
2012-12-20transcript level
1 14 0
2012-10-30protein level
1 12 0
2012-10-07protein level
1 12 0
2012-08-24protein level
1 10 0
2012-07-28protein level
1 10 0
2012-06-08protein level
1 11 0
2012-05-07protein level
1 10 0
2012-04-10protein level
1 10 0
2012-01-13protein level
1 7 0
2011-12-20protein level
1 7 0
2011-11-11protein level
1 7 0
2011-08-23protein level
1 7 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9BYQ4-1
3 0 2 18272.5379
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1044640,EBI-740019 PLSCR1  
  .positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity
.regulation of Fc receptor mediated stimulatory signaling pathway
.defense response to virus
  + 11 more...
.CD4 receptor binding
.enzyme binding
.phospholipid scramblase activity
  + 5 more...
.extracellular exosome
.membrane raft
.extracellular matrix
  + 7 more...
2 EBI-1044640,EBI-742487 SPRY2  
  .positive regulation of protein serine/threonine kinase activity
.positive regulation of ERK1 and ERK2 cascade
.negative regulation of ERK1 and ERK2 cascade
  + 19 more...
.protein serine/threonine kinase activator activity
.protein serine/threonine kinase inhibitor activity
.protein kinase binding
.ruffle membrane
.microtubule cytoskeleton
.plasma membrane
  + 2 more...
3 EBI-1044640,EBI-1053424 PRKAB2  
  .membrane organization
.regulation of protein kinase activity
.small molecule metabolic process
  + 13 more...
.identical protein binding .AMP-activated protein kinase complex
.cytosol
.nucleoplasm
4 EBI-1044640,EBI-947402 MAPKBP1  
  .N/A .N/A .N/A
5 EBI-1044640,EBI-374781 GLRX3  
  .cell redox homeostasis
.negative regulation of cardiac muscle hypertrophy
.regulation of the force of heart contraction
.iron-sulfur cluster binding
.metal ion binding
.poly(A) RNA binding
  + 2 more...
.extracellular exosome
.Z disc
.cell cortex
6 EBI-1044640,EBI-742764 PDE9A  
  .cGMP-mediated signaling
.metabolic process
.blood coagulation
.signal transduction
.3',5'-cyclic-GMP phosphodiesterase activity
.metal ion binding
.3',5'-cyclic-nucleotide phosphodiesterase activity
.perinuclear region of cytoplasm
.perikaryon
.ruffle membrane
  + 3 more...
7 EBI-1044640,EBI-3909284 GATA1  
  .negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
.negative regulation of transcription regulatory region DNA binding
.cellular response to thyroid hormone stimulus
  + 26 more...
.C2H2 zinc finger domain binding
.sequence-specific DNA binding
.chromatin DNA binding
  + 12 more...
.transcriptional repressor complex
.transcription factor complex
.nucleoplasm
.nucleus
8 EBI-1044640,EBI-3958099 KRTAP5-9  
  .epidermis development .N/A .keratin filament
9 EBI-1044640,EBI-747133 COL8A1  
  .epithelial cell proliferation
.camera-type eye morphogenesis
.endodermal cell differentiation
  + 6 more...
.N/A .extracellular exosome
.intracellular membrane-bounded organelle
.endoplasmic reticulum lumen
  + 2 more...
10 EBI-1044640,EBI-745213 AQP1  
  .cation transmembrane transport
.maintenance of symbiont-containing vacuole by host
.ammonium transmembrane transport
  + 60 more...
.carbon dioxide transmembrane transporter activity
.nitric oxide transmembrane transporter activity
.transmembrane transporter activity
  + 8 more...
.extracellular exosome
.apical part of cell
.axon terminus
  + 12 more...
11 EBI-1044640,EBI-740446 OTX1  
  .diencephalon morphogenesis
.positive regulation of transcription from RNA polymerase II promoter
.inner ear morphogenesis
  + 3 more...
.RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.RNA polymerase II core promoter proximal region sequence-specific DNA binding
.nucleus
12 EBI-1044640,EBI-740785 HOXA1  
  .cochlea morphogenesis
.cochlea development
.cellular response to retinoic acid
  + 24 more...
.sequence-specific DNA binding .nucleus
13 EBI-1044640,EBI-750494 SMCP  
  .sperm motility
.penetration of zona pellucida
.N/A .mitochondrial membrane
.mitochondrion
.cytoplasm
14 EBI-1044640,EBI-10172150 KRTAP10-5  
  .N/A .identical protein binding .keratin filament
15 EBI-1044640,EBI-10172290 KRTAP10-7  
  .N/A .identical protein binding .keratin filament
16 EBI-1044640,EBI-10171774 KRTAP10-8  
  .N/A .N/A .keratin filament
17 EBI-1044640,EBI-10172052 KRTAP10-9  
  .N/A .N/A .keratin filament
18 EBI-1044640,EBI-10217483 KRTAP10-11  
  .N/A .N/A .keratin filament
19 EBI-1044640,EBI-2688673 TMSB10  
  .sequestering of actin monomers
.actin filament organization
.N/A .cytoskeleton
.cytoplasm
20 EBI-1044640,EBI-10192698 CREB5  
  .adipose tissue development
.positive regulation of transcription, DNA-templated
.fat cell differentiation
.transcription from RNA polymerase II promoter
.metal ion binding
.sequence-specific DNA binding
.sequence-specific DNA binding transcription factor activity
.RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.extracellular exosome
.nucleus
21 EBI-1044640,EBI-2510602 JOSD1  
  .N/A .omega peptidase activity .membrane
.plasma membrane
.cytoplasm
22 EBI-1044640,EBI-751192 FAM76B  
  .protein deneddylation .NEDD8-specific protease activity .nuclear membrane
.nuclear speck
.cytoplasm
  + 2 more...
23 EBI-1044640,EBI-10245456 LCE3E  
  .keratinization .N/A .N/A
24 EBI-1044640,EBI-10245913 LCE1B  
  .keratinization .N/A .N/A
25 EBI-1044640,EBI-10246358 LCE4A  
  .keratinization .N/A .N/A
26 EBI-1044640,EBI-10246607 LCE2A  
  .keratinization .N/A .N/A
27 EBI-1044640,EBI-10250562 KRTAP5-6  
  .N/A .N/A .keratin filament
28 EBI-1044640,EBI-3957672 KRTAP26-1  
  .N/A .N/A .intermediate filament
29 EBI-1044640,EBI-8635958 SPATA8  
  .N/A .N/A .N/A
30 EBI-1044640,EBI-10173507 ADAMTSL4  
  .cellular protein metabolic process
.post-translational protein modification
.positive regulation of apoptotic process
  + 4 more...
.metalloendopeptidase activity
.protease binding
.endoplasmic reticulum lumen
.interstitial matrix
31 EBI-1044640,EBI-945833 NOTCH2NL  
  .cell differentiation
.multicellular organismal development
.Notch signaling pathway
.calcium ion binding .cytoplasm
.extracellular region
32 EBI-1044640,EBI-355471 CCDC28A  
  .N/A .N/A .N/A
33 EBI-1044640,EBI-716933 ARFGAP1  
  .membrane organization
.COPI coating of Golgi vesicle
.cellular protein metabolic process
  + 5 more...
.zinc ion binding
.GTPase activator activity
.synapse
.Golgi-associated vesicle membrane
.cytosol
34 EBI-1044640,EBI-744545 CATSPER1  
  .membrane depolarization during action potential
.calcium ion import
.regulation of cilium beat frequency involved in ciliary motility
  + 9 more...
.voltage-gated calcium channel activity
.calcium activated cation channel activity
.CatSper complex
.motile cilium
.plasma membrane
35 EBI-1044640,EBI-739832 LNX1  
  .protein homooligomerization
.protein ubiquitination involved in ubiquitin-dependent protein catabolic process
.ligase activity
.zinc ion binding
.ubiquitin-protein transferase activity
.cytoplasm
36 EBI-1044640,EBI-7199479 PTPMT1  
  .inositol phosphate dephosphorylation
.glycerophospholipid biosynthetic process
.small molecule metabolic process
  + 4 more...
.phosphatidylglycerophosphatase activity
.protein tyrosine/serine/threonine phosphatase activity
.protein tyrosine phosphatase activity
.phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
.integral component of mitochondrial inner membrane
.mitochondrion
.nucleus
37 EBI-1044640,EBI-448771 DOCK2  
  .positive regulation of phagocytosis
.regulation of defense response to virus by virus
.alpha-beta T cell proliferation
  + 12 more...
.T cell receptor binding
.Rac guanyl-nucleotide exchange factor activity
.extracellular exosome
.membrane
.endomembrane system
  + 2 more...
38 EBI-1044640,EBI-10225152 RNF31  
  .positive regulation of protein targeting to mitochondrion
.protein linear polyubiquitination
.positive regulation of NF-kappaB transcription factor activity
  + 4 more...
.ubiquitin binding
.ubiquitin protein ligase binding
.ligase activity
  + 2 more...
.LUBAC complex
.CD40 receptor complex
.cytoplasmic side of plasma membrane
.cytoplasm
39 EBI-1044640,EBI-741158 WDYHV1  
  .cellular protein modification process .protein-N-terminal glutamine amidohydrolase activity .cytosol
.nucleus
40 EBI-1044640,EBI-947779 RCHY1  
  .error-free translesion synthesis
.protein autoubiquitination
.protein ubiquitination involved in ubiquitin-dependent protein catabolic process
  + 5 more...
.protein homodimerization activity
.ligase activity
.zinc ion binding
  + 2 more...
.nuclear speck
.cytoplasm
.nucleoplasm
  + 2 more...
41 EBI-1044640,EBI-739863 KRTAP4-12  
  .N/A .N/A .keratin filament
42 EBI-1044640,EBI-10185730 KRTAP9-4  
  .N/A .N/A .keratin filament
43 EBI-1044640,EBI-10302547 KRTAP4-7  
  .hair cycle
.aging
.N/A .keratin filament
44 EBI-1044640,EBI-10172511 KRTAP4-2  
  .N/A .N/A .keratin filament
45 EBI-1044640,EBI-751260 KRTAP3-2  
  .N/A .structural molecule activity .keratin filament
46 EBI-1044640,EBI-947551 CHRD  
  .positive regulation of cell adhesion
.negative regulation of osteoblast differentiation
.floor plate development
  + 9 more...
.cytokine binding
.heparin binding
.extracellular space
47 EBI-1044640,EBI-10313866 C19orf66  
  .N/A .N/A .N/A
48 EBI-1044640,EBI-4291090 GNE  
  .carbohydrate phosphorylation
.cellular protein metabolic process
.post-translational protein modification
  + 6 more...
.metal ion binding
.N-acylmannosamine kinase activity
.UDP-N-acetylglucosamine 2-epimerase activity
  + 2 more...
.cytosol
.cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
heart33
Developmental Stage
TissuesTPM*
fetus5
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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