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> Protein (NX_Q9BZ29)
Protein (NX_Q9BZ29)
Protein
Gene SymbolDOCK9 to neXtProt (NX_Q9BZ29)
DescriptionDedicator of cytokinesis protein 9
Chromosome13
Location13q32.3 (99445741 ~ 99738879) to Ensembl
Sequene Features : Isoforms 5, Variants 175, PTMs 13 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.blood coagulation
.small GTPase mediated signal transduction
.Rho guanyl-nucleotide exchange factor activity .membrane
.endomembrane system
.cytosol
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
5 175 13
2014-09-19protein level
5 129 13
2014-05-27protein level
5 129 13
2014-02-25protein level
5 128 13
2013-12-09protein level
5 94 13
2013-11-01protein level
5 94 13
2013-09-12protein level
5 94 13
2013-08-17protein level
5 94 13
2013-07-15protein level
5 60 13
2013-06-11protein level
5 60 13
2013-02-12protein level
4 23 23
2012-12-20protein level
4 21 23
2012-10-30protein level
4 34 23
2012-10-07protein level
4 34 6
2012-08-24protein level
4 21 6
2012-07-28protein level
4 21 6
2012-06-08protein level
4 2 6
2012-05-07protein level
4 2 6
2012-04-10protein level
4 2 6
2012-01-13protein level
4 2 6
2011-12-20protein level
4 2 6
2011-11-11protein level
4 2 3
2011-08-23protein level
4 2 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9BZ29-1
0 103 3 236294.3499
NX_Q9BZ29-3
1 102 3 235210.9401
NX_Q9BZ29-4
3 101 3 238692.6327
NX_Q9BZ29-5
0 101 3 236274.1234
NX_Q9BZ29-6
1 62 1 142559.321
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2695893,EBI-1049657 NEB  
  .regulation of actin filament length
.muscle filament sliding
.somatic muscle development
.muscle organ development
.structural constituent of muscle .extracellular exosome
.Z disc
.actin cytoskeleton
.cytosol
2 EBI-2695893,EBI-347161 SMAD3  
  .positive regulation of extracellular matrix assembly
.activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
.extrinsic apoptotic signaling pathway
  + 73 more...
.R-SMAD binding
.co-SMAD binding
.transcription regulatory region DNA binding
  + 21 more...
.SMAD2-SMAD3 protein complex
.SMAD protein complex
.receptor complex
  + 8 more...
3 EBI-2695893,EBI-1040141 SMAD2  
  .positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry
.response to cholesterol
.SMAD protein signal transduction
  + 42 more...
.R-SMAD binding
.I-SMAD binding
.co-SMAD binding
  + 15 more...
.SMAD2-SMAD3 protein complex
.SMAD protein complex
.activin responsive factor complex
  + 6 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue233
adrenal gland30
blood24
bone41
brain92
cervix20
connective tissue40
embryonic tissue37
eye81
intestine47
kidney37
larynx42
liver9
lung47
lymph node89
mammary gland46
mouth105
muscle56
ovary49
pancreas46
parathyroid97
pharynx73
placenta105
prostate1092
skin42
spleen37
stomach41
testis22
thymus25
thyroid64
trachea38
umbilical cord72
uterus68
vascular96
Health State
TissuesTPM*
normal126
adrenal tumor79
breast (mammary gland) tumor42
cervical tumor28
chondrosarcoma60
colorectal tumor26
gastrointestinal tumor33
germ cell tumor11
glioma9
head and neck tumor89
kidney tumor43
leukemia31
liver tumor20
lung tumor19
non-neoplasia82
ovarian tumor65
pancreatic tumor9
prostate cancer19
retinoblastoma215
skin tumor39
soft tissue/muscle tissue tumor47
uterine tumor44
Developmental Stage
TissuesTPM*
adult164
embryoid body85
blastocyst16
neonate32
fetus57
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue60.8
adrenal gland16.8
appendix24.6
bone marrow4.5
cerebral cortex35.9
colon28
duodenum16.9
esophagus87.3
gallbladder40
heart muscle34.8
kidney25.4
liver9.7
lung77.4
lymph node34.7
ovary25.8
pancreas10.7
placenta88.7
prostate26.7
salivary gland33.9
skin68.2
small intestine19.8
spleen17.2
stomach17.9
testis20
thyroid gland85.1
urinary bladder39.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*607325, gene) Dedicator of cytokinesis 9; DOCK9OMIM


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