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> Protein (NX_Q9BZW7)
Protein (NX_Q9BZW7)
Protein
Gene SymbolTSGA10 to neXtProt (NX_Q9BZW7)
DescriptionTestis-specific gene 10 protein
Chromosome2
Location2q11.2 (99613724 ~ 99771427) to Ensembl
Sequene Features : Isoforms 2, Variants 99, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cell projection assembly
.spermatogenesis
.N/A .neuron projection
.nuclear membrane
.motile cilium
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 99 1
2014-09-19protein level
2 75 1
2014-05-27protein level
2 75 1
2014-02-25protein level
1 75 1
2013-12-09protein level
1 61 1
2013-11-01protein level
1 59 1
2013-09-12protein level
1 59 1
2013-08-17protein level
1 59 1
2013-07-15protein level
1 33 1
2013-06-11protein level
1 33 1
2013-02-12protein level
1 19 3
2012-12-20protein level
1 18 3
2012-10-30protein level
1 26 3
2012-10-07protein level
1 26 3
2012-08-24protein level
1 20 3
2012-07-28protein level
1 20 3
2012-06-08protein level
1 24 3
2012-05-07protein level
1 24 3
2012-04-10protein level
1 24 3
2012-01-13protein level
1 10 3
2011-12-20protein level
1 10 3
2011-11-11protein level
1 10 3
2011-08-23protein level
1 10 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_Q9BZW7-1
21 15 0 81369.7931
NX_Q9BZW7-2
0 15 0 34705.5485
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-744794,EBI-744471 ZBTB24  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.hematopoietic progenitor cell differentiation
.metal ion binding
.DNA binding
.nucleus
2 EBI-744794,EBI-7543896 SCEL  
  .keratinocyte differentiation
.embryo development
.epidermis development
.zinc ion binding .extracellular exosome
.cytoplasm
.cornified envelope
3 EBI-744794,EBI-10192698 CREB5  
  .adipose tissue development
.positive regulation of transcription, DNA-templated
.fat cell differentiation
.transcription from RNA polymerase II promoter
.metal ion binding
.sequence-specific DNA binding
.sequence-specific DNA binding transcription factor activity
.RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.extracellular exosome
.nucleus
4 EBI-744794,EBI-746238 CDK18  
  .N/A .ATP binding
.cyclin-dependent protein serine/threonine kinase activity
.N/A
5 EBI-744794,EBI-717810 AES  
  .positive regulation of anoikis
.negative regulation of canonical Wnt signaling pathway
.response to interleukin-1
  + 12 more...
.transcription corepressor activity .nucleus
6 EBI-744794,EBI-514538 BIRC2  
  .regulation of reactive oxygen species metabolic process
.regulation of cysteine-type endopeptidase activity
.inhibition of cysteine-type endopeptidase activity involved in apoptotic process
  + 40 more...
.protein N-terminus binding
.cysteine-type endopeptidase inhibitor activity involved in apoptotic process
.ligase activity
  + 3 more...
.membrane raft
.CD40 receptor complex
.cytoplasmic side of plasma membrane
  + 4 more...
7 EBI-744794,EBI-10217913 RTP5  
  .N/A .N/A .integral component of membrane
8 EBI-744794,EBI-710310 TCEA2  
  .positive regulation of transcription from RNA polymerase II promoter
.regulation of DNA-templated transcription, elongation
.DNA-templated transcription, elongation
.zinc ion binding
.DNA binding
.transcription elongation factor complex
.centrosome
.nucleoplasm
9 EBI-744794,EBI-2555767 ZNF124  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
10 EBI-744794,EBI-10246152 SYT6  
  .acrosomal vesicle exocytosis
.calcium ion-dependent exocytosis of neurotransmitter
.regulation of calcium ion-dependent exocytosis
  + 2 more...
.protein homodimerization activity
.clathrin binding
.syntaxin binding
.calcium ion binding
.perinuclear endoplasmic reticulum
.synaptic vesicle membrane
.cell junction
  + 4 more...
11 EBI-744794,EBI-2841978 ZNF544  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
12 EBI-744794,EBI-2557469 PPP1R18  
  .N/A .N/A .cytoskeleton
.cytoplasm
13 EBI-744794,EBI-930143 CDC73  
  .negative regulation of G1/S transition of mitotic cell cycle
.cellular response to lipopolysaccharide
.negative regulation of epithelial cell proliferation
  + 17 more...
.RNA polymerase II core binding .Cdc73/Paf1 complex
.nucleoplasm
.nucleus
14 EBI-744794,EBI-720304 ZNF410  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
15 EBI-744794,EBI-10181988 CEP57L1  
  .microtubule anchoring .N/A .microtubule
.microtubule organizing center
.cytoplasm
16 EBI-744794,EBI-741724 SPERT  
  .N/A .N/A .cytoplasmic membrane-bounded vesicle
17 EBI-744794,EBI-474076 PPHLN1  
  .keratinization .poly(A) RNA binding .intracellular membrane-bounded organelle
.Golgi apparatus
.cytoplasm
.nucleoplasm
18 EBI-744794,EBI-740727 ZNF417  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
19 EBI-744794,EBI-10175300 CCHCR1  
  .cell differentiation
.multicellular organismal development
.protein export from nucleus
.N/A .centriole
.cytoplasm
.nucleus
20 EBI-744794,EBI-10244131 FBF1  
  .establishment of epithelial cell polarity
.apical junction assembly
.cilium assembly
.organelle organization
.N/A .ciliary transition fiber
.cell junction
.cytosol
  + 3 more...
21 EBI-744794,EBI-8653994 ZNF599  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
22 EBI-744794,EBI-6427977 ZNF587  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
23 EBI-744794,EBI-745276 ZNF670  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
24 EBI-744794,EBI-10297542 ZNF2  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.zinc ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
25 EBI-744794,EBI-743265 ZNF426  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
26 EBI-744794,EBI-744115 CEP44  
  .N/A .N/A .midbody
.centrosome
.cytoplasm
.spindle pole
27 EBI-744794,EBI-712912 CBX8  
  .cellular protein metabolic process
.post-translational protein modification
.protein sumoylation
  + 3 more...
.methylated histone binding
.ubiquitin-protein transferase activity
.single-stranded RNA binding
.PRC1 complex
.PcG protein complex
.nucleoplasm
  + 3 more...
28 EBI-744794,EBI-743428 RCOR3  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.chromatin binding
.DNA binding
.nucleus
29 EBI-744794,EBI-10172526 MID2  
  .negative regulation of viral release from host cell
.positive regulation of NF-kappaB transcription factor activity
.positive regulation of sequence-specific DNA binding transcription factor activity
  + 6 more...
.phosphoprotein binding
.protein heterodimerization activity
.protein homodimerization activity
  + 3 more...
.extracellular exosome
.microtubule
.cytoplasm
30 EBI-744794,EBI-1105370 ZNF490  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder33
bone marrow20
brain6
eye4
kidney9
lung8
mammary gland6
muscle28
pancreas28
placenta3
prostate5
skin4
stomach10
testis170
trachea57
uterus12
Health State
TissuesTPM*
normal16
breast (mammary gland) tumor10
gastrointestinal tumor8
germ cell tumor3
glioma9
leukemia10
non-neoplasia10
soft tissue/muscle tissue tumor7
uterine tumor11
Developmental Stage
TissuesTPM*
adult8
fetus14
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue8.6
adrenal gland2.9
appendix3.1
bone marrow3.7
cerebral cortex4.4
colon3.4
duodenum6.8
esophagus1.7
gallbladder2.8
heart muscle1
kidney6.5
lung4.5
lymph node3.2
ovary3.8
pancreas3.4
placenta1.9
prostate4
salivary gland3.4
skin4.4
small intestine3.2
spleen3
stomach4.7
testis76.7
thyroid gland12.1
urinary bladder1.3
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*607166, gene) Testis-specific protein 10; TSGA10OMIM


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